10 completed, 2 unknown, 1 recruiting, 1 terminated. 4 Not applicable, 3 Phase 3, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 2 |
Follow Glaucoma and Ocular Hypertension: new trials by email Literature Review of Glaucoma and Ocular Hypertension trials Research Report on Glaucoma and Ocular Hypertension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring miLens system - Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder) | Completed | Smartlens, Inc. | 86 | 2025-02-19 | 2026-04-01 | |
| Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients Nanodropper adaptor, Original eyedrop bottle/No Nanodropper - Glaucoma, Glaucoma, Open-Angle | Not applicable | Completed | Nanodropper, Inc. | 420 | 2021-11-06 | 2023-01-18 |
| Clarifying the Optimal Application of SLT Therapy Trial Low Energy SLT, Standard Energy SLT - Glaucoma and Ocular Hypertension | Phase 3 | Recruiting | University of Pittsburgh | 790 | 2021-09-07 | 2026-08-14 |
| Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo) Boston keratoprosthesis type 1 and anterior hyaloid membrane peeling assisted by endoscopy - Corneal Transplantation, Glaucoma and Ocular Hypertension | Not applicable | Unknown | Centre hospitalier de l'Université de Montréal (CHUM) | 20 | 2020-04-08 | 2023-07-27 |
| A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study DE-117 Ophthalmic Solution, Timolol Maleate Ophthalmic Solution 0.5% - Glaucoma and Ocular Hypertension | Phase 3 | Completed | Santen Inc. | 417 | 2018-09-27 | 2023-08-09 |
| A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study DE-117 Ophthalmic Solution, Timolol Maleate Ophthalmic Solution 0.5% - Glaucoma and Ocular Hypertension | Phase 3 | Completed | Santen Inc. | 426 | 2018-09-14 | 2023-08-30 |
| Effect of Dexamethasone Implant on Optic Disc intravitreal dexamethasone implant application - Glaucoma and Ocular Hypertension, Diabetic Macular Edema | Completed | Bulent Ecevit University | 43 | 2018-02-01 | 2019-05-13 | |
| Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma MicroPulse® P3 Glaucoma Device (MP3) - Glaucoma, Glaucoma, Open-Angle | Not applicable | Completed | Centre hospitalier de l'Université de Montréal (CHUM) | 52 | 2017-06-19 | 2021-10-08 |
| Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma ENV515-3 Travoprost XR, ENV515-1 Travoprost XR, ENV515-3-2 Travoprost XR - Glaucoma and Ocular Hypertension | Phase 2 | Completed | Envisia Therapeutics | 41 | 2015-01-01 | 2019-10-17 |
| Prospective,Randomized,Controlled Study to Assess Efficacy,Safety, and Tolerability of SLT vs. PLT in Patients With POAG Selective laser trabeculoplasty (SLT), Pattern laser trabeculoplasty (PLT) - Glaucoma and Ocular Hypertension | Not applicable | Terminated | University Hospital, Geneva | 29 | 2014-04-01 | 2023-05-18 |
| Combined Ex-PRESS Implantation Alone or With Phacoemulsification for Glaucoma Associated With Cataract Glaucoma and Ocular Hypertension | Unknown | Hillel Yaffe Medical Center | 100 | 2014-03-01 | 2014-08-06 | |
| Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension Brimonidine Tartrate 0.025%, Vehicle - Glaucoma and Ocular Hypertension | Phase 1 | Completed | Eye Therapies, LLC | 15 | 2012-09-01 | 2012-12-25 |
| A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT DE-117, 0.0015% tafluprost, DE-117 and 0.0015% tafluprost - Glaucoma and Ocular Hypertension | Phase 1 / Phase 2 | Completed | Santen Inc. | 60 | 2012-07-01 | 2018-04-18 |
| Artificial Intelligence for Staging Glaucoma Severity: A Comparison With an Eye Specialist Using Visual Field Tests Artificial Intelligence GSS2 Staging - Glaucoma and Ocular Hypertension | Completed | University of Salerno | 50 | 2011-04-15 | 2026-09-15 |
Glaucoma (14) · Ocular Hypertension (14) · Glaucoma, Open-Angle (3) · Glaucoma, Angle-Closure (1) · Glaucoma, Neovascular (1) · Low Tension Glaucoma (1) · Optic Nerve Diseases (1) · Postoperative Complications (1)
Eye Diseases (14) · Cranial Nerve Diseases (1) · Nervous System Diseases (1) · Optic Nerve Diseases (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
tafluprost (1)
Santen Inc. (3) · Centre hospitalier de l'Université de Montréal (CHUM) (2) · Bulent Ecevit University (1) · Envisia Therapeutics (1) · Eye Therapies, LLC (1) · Hillel Yaffe Medical Center (1) · Nanodropper, Inc. (1) · Smartlens, Inc. (1) · University Hospital, Geneva (1) · University of Pittsburgh (1) · University of Salerno (1)
United States (7) · Canada (3) · India (1) · Italy (1) · Switzerland (1) · Turkey (Türkiye) (1)
Atilla Alpay, Ass. Prf. (1) · Goundappa K Balasubramani, PhD (1) · Harmanjit Singh, MD (1) · Jennifer Steger, PhD (1) · Kaweh Mansouri (1) · Michael Marchand, MD (1) · Mona Harissi-Dagher, MD (1) · Rana N Hanna, M.D (1) · Stephen Wisniewski, PhD (1) · Tony Realini, MD, MPH (1)
PMID 33577756, PMID 35943114, PMID 41886500
2UG1EY031651-06 (1), UG1EY031651 (1)