Factor X Deficiency: Clinical Trials

3 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 4 Phase 3.

By phase and status

Phase	Trials	Status
Phase 3	4	Completed 2, Terminated 1, Withdrawn 1

Follow Factor X Deficiency: new trials by email Literature Review of Factor X Deficiency trials Research Report on Factor X Deficiency

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Database For The Collection Of Clinical, Laboratory, And Treatment Data From Patients With Factor X Deficiency To Define The Natural History Of The Disease And Improve Patient Management Factor X Deficiency		Recruiting	Fondazione Luigi Villa	20	2026-06-14	2026-10-20
A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis Coagadex(R) - Acquired Factor X Deficiency	Phase 3	Withdrawn	Kedrion S.p.A.		2026-06-01	2026-11-05
Early Check: Expanded Screening in Newborns Confirmatory Testing - Spinal Muscular Atrophy, Fragile X Syndrome		Active not recruiting	RTI International	30000	2018-10-15	2026-07-01
Registry Study of COAGADEX® Patients With Moderate or Severe Hereditary Factor X Deficiency Undergoing Major Surgery Coagadex - Factor 10 Deficiency		Completed	Bio Products Laboratory	3	2018-02-27	2021-11-12
A Study to Investigate Bio Product Laboratory Ltd (BPL's) Factor X in the Prophylaxis of Bleeding in Children <12 Years FACTOR X - Factor X Deficiency	Phase 3	Completed	Bio Products Laboratory	9	2015-04-01	2018-04-02
Safety & Efficacy of BPL's High Purity FACTOR X in Treatment of Factor X Deficient Subjects Undergoing Surgery FACTOR X - Factor X Deficiency	Phase 3	Terminated	Bio Products Laboratory	4	2011-03-01	2019-02-05
A Study Investigating Treatment Factor X in People With Factor X Deficiency Human Coagulation FACTOR X - Factor X Deficiency	Phase 3	Completed	Bio Products Laboratory	16	2010-01-01	2014-12-12

Narrower conditions

3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (1)  ·  3-Hydroxyacyl-CoA Dehydrogenase Deficiency (1)  ·  3-methylcrotonyl CoA carboxylase 1 deficiency (1)  ·  3-methylcrotonyl CoA carboxylase 2 deficiency (1)  ·  Acidemia, isovaleric (1)  ·  Acrodermatitis enteropathica (1)  ·  Adenine phosphoribosyltransferase deficiency (1)  ·  Adrenal hyperplasia, congenital, type 5 (1)  ·  Adrenocorticotropic hormone deficiency (1)  ·  Amaurosis congenita of Leber, type 2 (1)  ·  Anemia, Sickle Cell (1)  ·  Angelman Syndrome (1)  ·  Aortic Stenosis, Supravalvular (1)  ·  Arginine-Glycine Amidinotransferase Deficiency (1)

Broader conditions

Blood Coagulation Disorders, Inherited (7)  ·  Coagulation Protein Disorders (7)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7)  ·  Genetic Diseases, Inborn (7)  ·  Hemic and Lymphatic Diseases (7)  ·  Blood Coagulation Disorders (6)  ·  Hematologic Diseases (6)  ·  Hemorrhagic Disorders (6)  ·  Immune System Diseases (2)  ·  Metabolic Diseases (2)  ·  Neoplasms (2)  ·  Neoplasms by Histologic Type (2)  ·  Nutritional and Metabolic Diseases (2)  ·  Abnormalities, Multiple (1)  ·  Albinism (1)

Interventions

Factor X (4)

Sponsors

Bio Products Laboratory (4)  ·  Fondazione Luigi Villa (1)  ·  Kedrion S.p.A. (1)  ·  RTI International (1)

Countries

United States (4)  ·  United Kingdom (3)  ·  Spain (2)  ·  Turkey (Türkiye) (2)  ·  Germany (1)  ·  Italy (1)

Top investigators

Amy Shapiro, Dr (1)  ·  Curt Scharfe, MD, PhD (1)  ·  Flora Peyvandi, MD, PhD (1)  ·  Mirella Calcinai, MD (1)  ·  Ri Liesner, Dr (1)  ·  Tim Aldwinckle (1)

Results publications

PMID 29545231, PMID 31315600, PMID 35142618