3 unknown, 2 active not recruiting, 2 completed, 1 recruiting. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Unknown 3, Active not recruiting 2, Completed 2, Recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Endometrial Serous Adenocarcinoma: new trials by email Literature Review of Endometrial Serous Adenocarcinoma trials Research Report on Endometrial Serous Adenocarcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma Biospecimen Collection, Carboplatin, Computed Tomography - Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 360 | 2022-11-16 | 2026-10-02 |
| Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer Carboplatin, Computed Tomography, Paclitaxel - Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 813 | 2019-08-22 | 2026-10-21 |
| Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer Vaginal Cuff Brachytherapy, Short course vaginal cuff brachytherapy - Endometrial Clear Cell Adenocarcinoma, Endometrial Endometrioid Adenocarcinoma | Phase 3 | Recruiting | University of Utah | 188 | 2018-02-02 | 2025-12-12 |
| Trial of Cisplatin Plus Radiation Followed by Carbo and Taxol Vs. Sandwich Therapy of Carbo and Taxol Followed Radiation Then Further Carbo and Taxol Cisplatin, Carboplatin, Paclitaxel - Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma | Phase 3 | Completed | Women's Cancer Care Associates, LLC | 48 | 2015-03-01 | 2024-07-23 |
| Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer Carboplatin, Laboratory Biomarker Analysis, Metformin Hydrochloride - Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma | Phase 2 / Phase 3 | Unknown | Gynecologic Oncology Group | 469 | 2014-03-17 | 2021-09-30 |
| Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer Carboplatin, Cisplatin, Internal Radiation Therapy - Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma | Phase 3 | Unknown | Gynecologic Oncology Group | 813 | 2009-06-29 | 2021-10-19 |
| Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer 3-Dimensional Conformal Radiation Therapy, Carboplatin, Intensity-Modulated Radiation Therapy - Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma | Phase 3 | Unknown | Gynecologic Oncology Group | 601 | 2009-03-23 | 2019-03-20 |
| Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer Doxorubicin Hydrochloride, Cisplatin, Filgrastim - Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma | Phase 3 | Completed | Gynecologic Oncology Group | 659 | 2000-07-01 | 2015-05-19 |
Endometrial Neoplasms (2) · Carcinosarcoma (1) · Fatigue (1) · Neoplasms (1) · Neurotoxicity Syndromes (1) · Obesity (1)
Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases (2) · Genital Diseases, Female (2) · Genital Neoplasms, Female (2) · Neoplasms by Site (2) · Urogenital Diseases (2) · Urogenital Neoplasms (2) · Uterine Diseases (2) · Uterine Neoplasms (2) · Body Weight (1) · Chemically-Induced Disorders (1) · Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms, Complex and Mixed (1)
Paclitaxel (7) · Carboplatin (6) · Taxes (6) · Brachytherapy (3) · Cisplatin (3) · Radiation (2) · Radiotherapy (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · Doxorubicin (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Hyaluronoglucosaminidase (1) · Metformin (1) · Platinum (1) · Practice Guidelines as Topic (1)
Gynecologic Oncology Group (4) · National Cancer Institute (NCI) (2) · University of Utah (1) · Women's Cancer Care Associates, LLC (1)
United States (8) · South Korea (4) · Canada (3) · Puerto Rico (2) · Japan (1)
Britt K Erickson (1) · Cristina DeCesaris, MD (1) · Daniela E Matei (1) · Howard Homesley (1) · Joyce N Barlin, MD (1) · Marcus E Randall (1) · Ramez N Eskander (1) · Victoria L Bae-Jump (1)
PMID 30995174, PMID 31189035, PMID 34903380, PMID 36972022, PMID 37411031, PMID 38431043, PMID 39700442, PMID 40044930, PMID 40966692
U10CA180868 (5), U10CA027469 (4), U10CA180830 (1)