20 withdrawn. 20 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 20 | Withdrawn 20 |
| Phase 2 | 3 | Withdrawn 3 |
Follow Covid19: new trials by email Literature Review of Covid19 trials Research Report on Covid19
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of GSE and Xylitol (Xlear) on COVID-19 Symptoms and Time to PCR Negativisation in COVID-19 Patients GSE and Xylitol, Control Placebo - Covid19 | Phase 3 | Withdrawn | Larkin Community Hospital | 2021-12-16 | 2023-10-16 | |
| Evaluation of the Efficacy of Xylitol Nasal Spray Against SARS-CoV-2 Nasal Spray - Covid19 | Phase 3 | Withdrawn | Larkin Community Hospital | 2021-12-08 | 2023-10-16 | |
| A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19 CVnCoV Vaccine - Coronavirus, Covid19 | Phase 3 | Withdrawn | CureVac | 2021-10-01 | 2021-08-20 | |
| Efficacy, Safety, and Immunogenicity of Vaccine Reimmunization With a Third Homologous Versus Heterologous Dose Against COVID-19 in Patients Undergoing Solid Organ Transplantation. Janssen vaccine, Spikevax (Moderna) vaccine - Covid19 | Phase 3 | Withdrawn | Instituto de Investigación Marqués de Valdecilla | 2021-09-01 | 2023-03-02 | |
| BCG Against Covid-19 for Prevention and Amelioration of Severity Trial (BAC to the PAST) BCG Vaccine, Placebo - Covid19 | Phase 3 | Withdrawn | Harvard Medical School (HMS and HSDM) | 2021-09-01 | 2021-06-28 | |
| IntraDermal Versus Intramuscular Comirnaty® Efficacy Study Comirnaty® - Covid19 Vaccine, Covid19 | Phase 3 | Withdrawn | Department of Medical Services Ministry of Public Health of Thailand | 2021-08-31 | 2022-05-11 | |
| Corticosteroids for COVID-19 Prednisone, Point of Care testing device for C-reactive protein - Covid19 | Phase 3 | Withdrawn | University of Alberta | 2021-08-01 | 2022-04-14 | |
| Essential Amino Acid Supplementation in Older Adult COVID-19 Patients Essential amino acids, Maltodextrin - Covid19 | Phase 2 / Phase 3 | Withdrawn | University of Arkansas | 2021-05-01 | 2024-09-03 | |
| Outpatient Use of Ivermectin in COVID-19 Ivermectin Pill, Placebo - Covid19 | Phase 3 | Withdrawn | Temple University | 2021-04-01 | 2026-10-09 | |
| Use of Hypochlorous Acid as Prophylaxis in Health Personnel at High Risk of Infection by SARS-CoV 2 (COVID19) Stabilized hypochlorous acid, Placebo - SARS-CoV Infection, Covid19 | Phase 2 / Phase 3 | Withdrawn | Hospital Universitario San Ignacio | 2021-02-15 | 2023-03-03 | |
| Proxalutamide Treatment for COVID-19 Patients in Intensive Care Unit Proxalutamide, Placebo - Covid19, SARS (Severe Acute Respiratory Syndrome) | Phase 3 | Withdrawn | Applied Biology, Inc. | 2021-02-08 | 2022-03-04 | |
| DYNAMIC Study (DoxycYcliNe AMbulatoIre COVID-19) Doxycycline, Placebo - COVID19 | Phase 3 | Withdrawn | Nantes University Hospital | 2021-02-01 | 2022-04-20 | |
| Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection alpha1-proteinase inhibitor, Antiviral Agents - Covid19, Pneumonia, Viral | Phase 3 | Withdrawn | Blessing Corporate Services, Inc | 2021-01-01 | 2020-12-21 | |
| Proxalutamide Treatment for COVID-19 Female Outpatients Proxalutamide, Standard of Care - Covid19, SARS-CoV Infection | Phase 3 | Withdrawn | Applied Biology, Inc. | 2020-11-01 | 2022-03-04 | |
| Efficacy of BACMUNE (MV130) in the Prevention of Disease Due to COVID-19 Infection in Healthcare Personnel BACMUNE (MV130), Placebo - Covid19 | Phase 3 | Withdrawn | Inmunotek S.L. | 2020-10-01 | 2020-11-02 | |
| A Study to Evaluate the Efficacy of Xlear vs. Placebo for Acute COVID-19 Infection Xlear Nasal Spray, Placebo - Covid19 | Phase 3 | Withdrawn | Larkin Community Hospital | 2020-08-30 | 2023-10-16 | |
| Efficacy and Safety of Nitazoxanide 600 mg to Treat Mild Ambulatory COVID-19 Patients Nitazoxanide, Placebo - covid19 | Phase 2 / Phase 3 | Withdrawn | Azidus Brasil | 2020-07-01 | 2022-10-28 | |
| Phase 3 Open-Label Controlled Trial of Convalescent Plasma in Early COVID-19 Infection Convalescent Plasma, Standard of Care - Covid19 | Phase 3 | Withdrawn | Larkin Community Hospital | 2020-05-12 | 2023-10-16 | |
| Assessment of the Efficacy and Safety of (HCQ) as a Prophylaxis for COVID19 for Health Professionals Hydroxychloroquine (HCQ), Placebo oral tablet - COVID19, Sars-CoV2 | Phase 3 | Withdrawn | Abderrahmane Mami Hospital | 2020-04-28 | 2020-08-28 | |
| Hydroxychloroquine Azithromycin COVID-19 Pregnancy Trial Hydroxychloroquine and azithromycin treatment, conventional management of patients - COVID19 | Phase 3 | Withdrawn | Hospital St. Joseph, Marseille, France | 2020-04-01 | 2020-11-20 |
COVID-19 (20) · Severe Acute Respiratory Syndrome (4) · Coronavirus Infections (1) · Dyspnea (1) · Pneumonia, Viral (1) · Virus Diseases (1)
Coronaviridae Infections (20) · Infections (20) · Lung Diseases (20) · Nidovirales Infections (20) · Pneumonia (20) · RNA Virus Infections (20) · Respiratory Tract Diseases (20) · Respiratory Tract Infections (20) · Coronavirus Infections (19) · Pneumonia, Viral (19) · Virus Diseases (19) · Pathological Conditions, Signs and Symptoms (1) · Respiration Disorders (1) · Signs and Symptoms (1) · Signs and Symptoms, Respiratory (1)
Hydroxychloroquine (2) · Standard of Care (2) · proxalutamide (2) · 2019-nCoV Vaccine mRNA-1273 (1) · Amino Acids, Essential (1) · Antiviral Agents (1) · BCG Vaccine (1) · BNT162 Vaccine (1) · CVnCoV COVID-19 vaccine (1) · Doxycycline (1) · Ivermectin (1) · Nasal Sprays (1) · Prednisone (1) · Vaccines (1) · Xylitol (1)
Larkin Community Hospital (4) · Applied Biology, Inc. (2) · Abderrahmane Mami Hospital (1) · Azidus Brasil (1) · Blessing Corporate Services, Inc (1) · CureVac (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Harvard Medical School (HMS and HSDM) (1) · Hospital St. Joseph, Marseille, France (1) · Hospital Universitario San Ignacio (1) · Inmunotek S.L. (1) · Instituto de Investigación Marqués de Valdecilla (1) · Nantes University Hospital (1) · Temple University (1) · University of Alberta (1)
United States (7) · Brazil (2) · Mexico (2) · Colombia (1) · France (1) · Spain (1) · Tunisia (1)
Flavio Cadegiani, MD (2) · Andy Goren, MD (1) · Carlos Wambier, MD (1) · Daniel Fonseca, MD (1) · Edimilson Migowski, MD (1) · Gohar Azhar, MD (1) · Gustavo Ferrer, MD (1) · Humam Farah, MD (1) · Jalila Ben Khelil, Pr (1) · Juan Zambrano, MD. M.Sc. (1) · Megan B Murray, MD, ScD (1)