3 unknown, 2 completed, 2 recruiting, 1 withdrawn. 8 Phase 2, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Unknown 3, Completed 2, Recruiting 2, Withdrawn 1 |
| Phase 1 | 3 | Unknown 2, Completed 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
Follow Corneal Ectasia: new trials by email Literature Review of Corneal Ectasia trials Research Report on Corneal Ectasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia Riboflavin 0.1% ophthalmic solution and pulsed light, Riboflavin 0.1% ophthalmic solution and non-pulsed light - Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Recruiting | Price Vision Group | 500 | 2025-10-01 | 2026-09-25 |
| Safety and Effectiveness of the PXL-Platinum 330 System PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Corneal Ectasia, Keratoconus | Phase 1 / Phase 2 | Unknown | Colorado Eye Consultants/Cornea Consultants of Colorado | 300 | 2020-06-01 | 2022-01-25 |
| Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Keratoconus, Pellucid Marginal Corneal Degeneration | Phase 2 | Recruiting | Goodman Eye Center | 500 | 2019-10-19 | 2025-10-20 |
| Safety and Preliminary Efficacy of IVMED-80 Eye Drops in Keratoconus Patients IVMED-80, Placebo - Keratoconus, Corneal Ectasia | Phase 1 / Phase 2 | Completed | iVeena Delivery Systems, Inc. | 38 | 2019-02-08 | 2022-02-15 |
| Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL). UV-X 1000 (3 mW/cm²), UV-X 2000 (9 mW/cm²), riboflavin with hydroxypropyl methylcellulose - Keratoconus, Corneal Ectasia | Phase 1 / Phase 2 | Unknown | Oslo University Hospital | 40 | 2012-08-01 | 2016-08-30 |
| UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia UV-X Light, Riboflavin - Keratoconus, Ectasia | Phase 2 | Unknown | Mercy Center for Corrective Eye Surgery | 250 | 2011-03-01 | 2011-03-29 |
| Corneal Crosslinking in Keratoconus and Corneal Ectasia Riboflavin, Placebo - Progressive Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Withdrawn | Ohio State University | 2008-04-01 | 2017-04-20 | |
| Corneal Collagen Cross-Linking for the Treatment of Progressive Keratoconus and Corneal Ectasia Corneal collagen, Sham comparator - Progressive Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Completed | Emory University | 160 | 2007-12-01 | 2010-09-02 |
Keratoconus (8) · Corneal Diseases (3) · Dilatation, Pathologic (3) · Eye Diseases (1)
Eye Diseases (7) · Corneal Diseases (5) · Pathological Conditions, Anatomical (3) · Pathological Conditions, Signs and Symptoms (3)
Riboflavin (4) · Corneal Cross-Linking (2) · Hypromellose Derivatives (1) · Ophthalmic Solutions (1) · Radiation (1) · Radiotherapy (1)
Colorado Eye Consultants/Cornea Consultants of Colorado (1) · Emory University (1) · Goodman Eye Center (1) · Mercy Center for Corrective Eye Surgery (1) · Ohio State University (1) · Oslo University Hospital (1) · Price Vision Group (1) · iVeena Delivery Systems, Inc. (1)
United States (6) · Mexico (1)
Arturo Chayet, MD (1) · Balamurali K. Ambati, MD, PhD (1) · Francis Price, MD (1) · R. Doyle Stulting, MD, PhD (1) · Richard Keates, MD (1) · Robert L Epstein, MD (1) · S. Lance Forstot, M.D. (1)
PMID 16765803, PMID 16952090, PMID 18471635, PMID 18811118, PMID 20138607, PMID 20164744, PMID 25365551