6 unknown, 2 withdrawn, 1 completed, 1 recruiting. 11 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Unknown 6, Withdrawn 2, Completed 1, Recruiting 1, Terminated 1 |
| Phase 2 | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
Follow Corneal Ectasia: new trials by email Literature Review of Corneal Ectasia trials Research Report on Corneal Ectasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia Riboflavin 0.1% ophthalmic solution and pulsed light, Riboflavin 0.1% ophthalmic solution and non-pulsed light - Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Recruiting | Price Vision Group | 500 | 2025-10-01 | 2026-09-25 |
| Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A Light riboflavin ophthalmic solution - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 170 | 2021-07-30 | 2023-01-04 |
| Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal Ectasia Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2021-06-02 | 2023-01-04 |
| Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 170 | 2021-04-16 | 2023-01-04 |
| Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery riboflavin: 0.12% riboflavin ophthalmic solution with the KXL system, placebo: 0.0% riboflavin ophthalmic solution with the KXL system - Corneal Ectasia | Phase 3 | Withdrawn | Glaukos Corporation | 2012-07-01 | 2021-04-26 | |
| Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery KXL System (15 mW/cm2), KXL System (30 mW/cm2), KXL System (45 mW/cm2) - Keratoconus, Corneal Ectasia | Phase 3 | Terminated | American-European Congress of Ophthalmic Surgery | 1721 | 2012-07-01 | 2018-07-05 |
| Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2011-11-01 | 2023-02-08 |
| Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin Riboflavin/Dextran, Hypotonic Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2010-06-01 | 2023-02-08 |
| Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2010-04-01 | 2023-02-08 |
| Corneal Crosslinking in Keratoconus and Corneal Ectasia Riboflavin, Placebo - Progressive Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Withdrawn | Ohio State University | 2008-04-01 | 2017-04-20 | |
| Corneal Collagen Cross-Linking for the Treatment of Progressive Keratoconus and Corneal Ectasia Corneal collagen, Sham comparator - Progressive Keratoconus, Corneal Ectasia | Phase 2 / Phase 3 | Completed | Emory University | 160 | 2007-12-01 | 2010-09-02 |
Keratoconus (10) · Corneal Diseases (4) · Dilatation, Pathologic (2)
Eye Diseases (10) · Corneal Diseases (6) · Pathological Conditions, Anatomical (2) · Pathological Conditions, Signs and Symptoms (2)
Riboflavin (8) · Dextrans (2) · Corneal Cross-Linking (1) · Ophthalmic Solutions (1)
Cornea and Laser Eye Institute (6) · American-European Congress of Ophthalmic Surgery (1) · Emory University (1) · Glaukos Corporation (1) · Ohio State University (1) · Price Vision Group (1)
United States (10) · Puerto Rico (1)
Peter S Hersh, MD (3) · Peter Hersh, MD (2) · Steven A Greenstein, MD (2) · Francis Price, MD (1) · John Vukich, MD (1) · Peter Hersh, M.D. (1) · R. Doyle Stulting, MD, PhD (1) · Richard Keates, MD (1) · Vineeta Belanger (1)