3 completed, 3 unknown. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 3, Unknown 3 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
Follow Corneal Ectasia: new trials by email Literature Review of Corneal Ectasia trials Research Report on Corneal Ectasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Keratoconus, Pellucid Marginal Corneal Degeneration | Phase 1 | Completed | Cornea Associates of Texas | 249 | 2021-02-01 | 2025-02-11 |
| Safety and Effectiveness of the PXL-Platinum 330 System PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Corneal Ectasia, Keratoconus | Phase 1 / Phase 2 | Unknown | Colorado Eye Consultants/Cornea Consultants of Colorado | 300 | 2020-06-01 | 2022-01-25 |
| Safety and Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Keratoconus, Pellucid Marginal Corneal Degeneration | Phase 1 | Completed | Cornea Associates of Texas | 200 | 2020-01-10 | 2022-10-19 |
| Safety and Preliminary Efficacy of IVMED-80 Eye Drops in Keratoconus Patients IVMED-80, Placebo - Keratoconus, Corneal Ectasia | Phase 1 / Phase 2 | Completed | iVeena Delivery Systems, Inc. | 38 | 2019-02-08 | 2022-02-15 |
| Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2 Riboflavin 0.1% ophthalmic solution, CCL-VARIO UV lamp, CCL-VARIO at 18 mW/cm2 - Keratoconus, Corneal Ectasia | Phase 1 | Unknown | Robert Mack, M.D. | 100 | 2013-10-01 | 2015-12-14 |
| Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL). UV-X 1000 (3 mW/cm²), UV-X 2000 (9 mW/cm²), riboflavin with hydroxypropyl methylcellulose - Keratoconus, Corneal Ectasia | Phase 1 / Phase 2 | Unknown | Oslo University Hospital | 40 | 2012-08-01 | 2016-08-30 |
Keratoconus (6) · Dilatation, Pathologic (1)
Corneal Diseases (6) · Eye Diseases (6) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1)
Riboflavin (2) · Chromatin Immunoprecipitation Sequencing (1) · Corneal Cross-Linking (1) · Hypromellose Derivatives (1) · Ophthalmic Solutions (1) · Radiation (1) · Radiotherapy (1)
Cornea Associates of Texas (2) · Colorado Eye Consultants/Cornea Consultants of Colorado (1) · Oslo University Hospital (1) · Robert Mack, M.D. (1) · iVeena Delivery Systems, Inc. (1)
United States (4) · Mexico (1)
Arturo Chayet, MD (1) · Balamurali K. Ambati, MD, PhD (1) · Robert J Mack, M.D. (1) · S. Lance Forstot, M.D. (1) · Tyrone McCall, MD (1)