7 completed, 4 unknown, 1 active not recruiting, 1 recruiting. 14 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 14 | Completed 7, Unknown 4, Active not recruiting 1, Recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Chronic Rhinosinusitis With Nasal Polyps: new trials by email Literature Review of Chronic Rhinosinusitis With Nasal Polyps trials Research Report on Chronic Rhinosinusitis With Nasal Polyps
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study Lunsekimig, Mometasone furoate nasal spray (MFNS) - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Active not recruiting | Sanofi | 71 | 2025-05-12 | 2026-10-28 |
| Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS). Sinonasal microbiome transplant procedure., Placebo saline transplant - Chronic Rhinosinusitis Without Nasal Polyps, Chronic Rhinosinusitis With Nasal Polyps | Phase 2 / Phase 3 | Recruiting | Region Skane | 50 | 2024-10-14 | 2025-09-22 |
| A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps lunsekimig, placebo - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Completed | Sanofi | 79 | 2024-07-17 | 2026-04-28 |
| A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps 210mg of TQC2731 injection, 420mg of TQC2731 injection - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Completed | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 59 | 2024-07-04 | 2025-11-20 |
| Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis CM326, Placebo - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Unknown | Keymed Biosciences Co.Ltd | 90 | 2024-06-30 | 2024-04-18 |
| A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps Verekitug (UPB-101), Placebo - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Completed | Upstream Bio Inc. | 81 | 2023-12-18 | 2026-09-18 |
| Efficacy and Safety of SHR-1905 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps SHR-1905 Injection, SHR-1905 Placebo Injection - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Completed | Guangdong Hengrui Pharmaceutical Co., Ltd | 114 | 2023-09-04 | 2026-07-22 |
| The Study of Long-term Outcomes of GR1802 in Patients With Chronic Rhinosinusitis With Nasal Polyps GR1802 injection - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Unknown | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 70 | 2023-08-18 | 2023-08-29 |
| The Study of GR1802 in Patients with Chronic Rhinosinusitis with Nasal Polyps GR1802 injection, placebo - Chronic Rhinosinusitis with Nasal Polyps | Phase 2 | Unknown | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 70 | 2023-02-08 | 2024-09-25 |
| A Study of CM326 in Patients With Chronic Rhinosinusitis With Nasal Polyps CM326, Placebo - Chronic Rhinosinusitis With Nasal Polyps | Phase 1 / Phase 2 | Completed | Keymed Biosciences Co.Ltd | 88 | 2022-07-11 | 2024-11-08 |
| Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps. Montelukast, Prednisolone, Fluticasone Furoate - Montelukast, Chronic Rhinosinusitis With Nasal Polyps | Phase 1 / Phase 2 | Unknown | Assiut University | 60 | 2022-01-01 | 2022-03-18 |
| The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps CM310 - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Completed | Keymed Biosciences Co.Ltd | 46 | 2021-11-30 | 2024-11-08 |
| A Study to Evaluate CBP-201, Rademikibart, in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps CBP-201, Placebo - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 | Terminated | Connect Biopharm LLC | 40 | 2021-06-16 | 2023-10-17 |
| The Role of Budesonide Intrapolyp Injection in the Management of Type 2 Chronic Rhinosinusitis Budesonide, Prednisone, Saline - Chronic Rhinosinusitis With Nasal Polyps | Phase 2 / Phase 3 | Completed | Kafrelsheikh University | 120 | 2021-05-01 | 2023-07-05 |
Nasal Polyps (1) · Nose Diseases (1) · Otorhinolaryngologic Diseases (1) · Paranasal Sinus Diseases (1) · Respiratory Tract Diseases (1) · Sinusitis (1)
Infections (1) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1) · Polyps (1) · Respiratory Tract Infections (1)
Budesonide (1) · Prednisolone (1) · Prednisone (1) · Sodium Chloride (1) · fluticasone furoate (1) · montelukast (1)
Keymed Biosciences Co.Ltd (3) · Genrix (Shanghai) Biopharmaceutical Co., Ltd. (2) · Sanofi (2) · Assiut University (1) · Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. (1) · Connect Biopharm LLC (1) · Guangdong Hengrui Pharmaceutical Co., Ltd (1) · Kafrelsheikh University (1) · Region Skane (1) · Upstream Bio Inc. (1)
China (7) · Poland (4) · United States (4) · Argentina (2) · Belgium (2) · Bulgaria (2) · Egypt (2) · Spain (2) · United Kingdom (2) · Czechia (1) · Germany (1) · Sweden (1) · Ukraine (1)
Luo Zhang (2) · Suzhou Connect (1)
PMID 38482462, PMID 39393433, PMID 41022848
2023 (1)