4 completed, 4 terminated, 1 recruiting, 1 unknown. 10 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 10 | Completed 4, Terminated 4, Recruiting 1, Unknown 1 |
Follow Chronic Plaque Psoriasis: new trials by email Literature Review of Chronic Plaque Psoriasis trials Research Report on Chronic Plaque Psoriasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail Psoriasis Roflumilast 0.3% topical cream - Chronic Plaque Psoriasis, Nail Psoriasis | Phase 4 | Recruiting | Modern Research Associates, PLLC | 15 | 2026-09-15 | 2026-10-01 |
| Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis Secukinumab 300 mg, Placebo - Chronic Plaque Psoriasis | Phase 4 | Completed | Novartis Pharmaceuticals | 91 | 2016-02-10 | 2021-01-05 |
| Raptiva in Palm and Sole Psoriasis Efalizumab (Raptiva), Placebo - Chronic Plaque Psoriasis | Phase 4 | Terminated | Merck KGaA, Darmstadt, Germany | 6 | 2008-09-01 | 2014-02-13 |
| Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis efalizumab plus placebo, efalizumab plus acitretin - Chronic Plaque Psoriasis | Phase 4 | Unknown | Universita di Verona | 100 | 2008-09-01 | 2008-06-30 |
| TRUST Study: Raptiva ® in Hand & Foot Psoriasis Efalizumab - anti CD11a recombinant human monoclonal antibody, Placebo - Chronic Plaque Psoriasis | Phase 4 | Terminated | Merck KGaA, Darmstadt, Germany | 76 | 2008-04-01 | 2014-02-27 |
| Alefacept in Subjects With Chronic Plaque Psoriasis Who Failed to Respond to Anti-TNF Therapy alefacept - Chronic Plaque Psoriasis | Phase 4 | Terminated | John Murray | 1 | 2008-02-01 | 2013-02-22 |
| ChangE From Any Systemic psoriasiS therapY to Raptiva Efalizumab - anti CD11a recombinant human monoclonal antibody (mAb) - Chronic Plaque Psoriasis | Phase 4 | Terminated | Merck KGaA, Darmstadt, Germany | 70 | 2008-01-01 | 2014-02-13 |
| Study to Evaluate the Immune Response to Pneumococcal Vaccine in Alefacept-treated Adults With Chronic Plaque Psoriasis alefacept, polyvalent pneumococcal vaccine - Chronic Plaque Psoriasis | Phase 4 | Completed | Astellas Pharma Inc | 43 | 2007-07-01 | 2012-02-02 |
| Moderate Weight Loss Makes Obese Patients With Severe Chronic Plaque Psoriasis Responsive to Sub-Optimal Dose of Cyclosporine: an Investigator Blinded, Controlled, Randomized Clinical Trial low calorie diet - Chronic Plaque Psoriasis, Obesity | Phase 4 | Completed | Universita di Verona | 2005-11-01 | 2007-08-07 | |
| Safety and Tolerability of Repeat Courses of IM Alefacept Alefacept - Chronic Plaque Psoriasis | Phase 4 | Completed | Charite University, Berlin, Germany | 20 | 2004-02-01 | 2008-11-20 |
Psoriasis (4) · Margins of Excision (1) · Obesity (1) · Skin Diseases (1)
Skin Diseases, Papulosquamous (4) · Skin and Connective Tissue Diseases (4) · Skin Diseases (3) · Pathological Conditions, Signs and Symptoms (2) · Body Weight (1) · Morphological and Microscopic Findings (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1) · Overnutrition (1) · Overweight (1) · Signs and Symptoms (1)
Alefacept (3) · efalizumab (2) · Acitretin (1) · Caloric Restriction (1) · Pneumococcal Vaccines (1) · Roflumilast (1) · secukinumab (1)
Merck KGaA, Darmstadt, Germany (3) · Universita di Verona (2) · Astellas Pharma Inc (1) · Charite University, Berlin, Germany (1) · John Murray (1) · Modern Research Associates, PLLC (1) · Novartis Pharmaceuticals (1)
United States (3) · Canada (2) · Italy (2) · Austria (1) · Germany (1)
Giampiero Girolomoni (2) · Nicole Selenko-Gebauer, MD (2) · John C Murray, MD (1) · Nicole Selenko-Gebauer (1) · Wolfram Sterry, Prof. M.D. (1)