2 active not recruiting, 1 completed, 1 not yet recruiting, 1 unknown. 5 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Active not recruiting 2, Completed 1, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Chronic Graft Versus Host Disease: new trials by email Literature Review of Chronic Graft Versus Host Disease trials Research Report on Chronic Graft Versus Host Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host Disease Belumosudil, Best available therapy (BAT) - Chronic Graft Versus Host Disease | Phase 3 | Not yet recruiting | Sanofi | 356 | 2026-09-07 | 2026-09-15 |
| A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease. Belumosudil, Placebo, Prednisone - Chronic Graft Versus Host Disease | Phase 3 | Active not recruiting | Sanofi | 260 | 2024-01-23 | 2026-10-16 |
| Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) ibrutinib, Placebo, Prednisone - Chronic Graft Versus Host Disease | Phase 3 | Completed | Pharmacyclics LLC. | 193 | 2017-05-11 | 2023-03-30 |
| A Long-term Extension Study of PCI-32765 (Ibrutinib) Ibrutinib - Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | Phase 3 | Active not recruiting | Janssen Research & Development, LLC | 539 | 2013-09-09 | 2026-10-01 |
| Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Chronic Graft Versus Host Disease Biological: mesenchymal stem cell, Cyclosporine and Glucocorticoid - Chronic Graft Versus Host Disease | Phase 2 / Phase 3 | Unknown | Chinese Academy of Medical Sciences | 100 | 2012-02-01 | 2012-08-03 |
Bronchiolitis Obliterans Syndrome (5) · Graft vs Host Disease (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Lymphoma, Follicular (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Mantle-Cell (1) · Waldenstrom Macroglobulinemia (1)
Bronchial Diseases (5) · Bronchiolitis (5) · Bronchiolitis Obliterans (5) · Bronchitis (5) · Immune System Diseases (5) · Lung Diseases (5) · Lung Diseases, Obstructive (5) · Organizing Pneumonia (5) · Respiratory Tract Diseases (5) · Graft vs Host Disease (4) · Blood Protein Disorders (1) · Cardiovascular Diseases (1) · Chronic Disease (1) · Disease Attributes (1) · Hematologic Diseases (1)
Prednisone (2) · belumosudil (2) · ibrutinib (2) · Cyclosporine (1) · Glucocorticoids (1) · KD025 (1) · Prednisolone (1)
Sanofi (2) · Chinese Academy of Medical Sciences (1) · Janssen Research & Development, LLC (1) · Pharmacyclics LLC. (1)
China (4) · Australia (3) · Canada (3) · France (3) · Germany (3) · Italy (3) · South Korea (3) · Spain (3) · United States (3) · Argentina (2) · Austria (2) · Belgium (2) · Brazil (2) · Czechia (2) · Greece (2)
Chunhua Zhao, MD,PHD (1) · He Huang, MD (1) · Justin Wahlstrom, MD (1)
2023 (1)