5 recruiting, 2 completed, 2 withdrawn, 1 active not recruiting. 4 Not applicable, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Active not recruiting 1, Recruiting 1 |
| Phase 1 | 2 | Terminated 1, Withdrawn 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
Follow Centronuclear Myopathy: new trials by email Literature Review of Centronuclear Myopathy trials Research Report on Centronuclear Myopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease Whole-body Electrical Muscle Stimulation Exercise - Neuromuscular Diseases (NMD), Amyotrophic Lateral Sclerosis | Not applicable | Active not recruiting | University of Missouri-Columbia | 50 | 2026-03-10 | 2026-11-06 |
| Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy MSOT - Centronuclear Myopathy | Recruiting | University of Erlangen-Nürnberg Medical School | 40 | 2025-05-29 | 2025-06-15 | |
| The Prevalence of RYR1-related Disease Neuromuscular Disease, Malignant Hyperthermia | Not yet recruiting | King's College London | 2000 | 2025-02-01 | 2025-01-24 | |
| The Natural History and Muscle Fatigability of Patients With Congenital Myopathies. Natural history and non therapeutical therapy - Central Core Disease, Multi-Minicore Disease | Recruiting | Radboud University Medical Center | 100 | 2024-03-28 | 2024-08-19 | |
| Early Phase Human Drug Trial to Investigate DYN101 in Participants 2 to 17 Years With Centronuclear Myopathies DYN101 - Centronuclear Myopathy | Phase 1 / Phase 2 | Withdrawn | Dynacure | 2024-01-01 | 2022-07-11 | |
| Natural History Study of Patients With Centronuclear Myopathies Centronuclear Myopathy | Withdrawn | Dynacure | 2022-09-01 | 2022-07-11 | ||
| Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment Salbutamol (as Salbutamol Sulfate) 2 Mg Oral Tablet, Salbutamol Only Product in Oral Dose Form - Congenital Myopathy, Neuromuscular Diseases | Not applicable | Completed | Vastra Gotaland Region | 18 | 2021-10-25 | 2025-06-19 |
| Assessments in Patients With Muscular Pathology and in Control Subjects : The ActiLiège Next Study ActiMyo/Syde - Duchenne Muscular Dystrophy, Fascioscapulohumeral Muscular Dystrophy | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 300 | 2020-07-10 | 2025-05-20 |
| Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies DYN101 - Centronuclear Myopathy | Phase 1 / Phase 2 | Terminated | Dynacure | 14 | 2020-01-09 | 2023-06-27 |
| Prospective Natural History Study of Patients With Myotubular Myopathy and Other CentroNuclear Myopathies Standardized strength, respiratory and motor function assessments - Centronuclear Myopathy | Not applicable | Completed | Institut de Myologie, France | 60 | 2017-05-28 | 2023-03-02 |
| Myotubular and Centronuclear Myopathy Patient Registry Myotubular Myopathy, Myotubular Myopathy 1 | Recruiting | Newcastle-upon-Tyne Hospitals NHS Trust | 500 | 2013-03-26 | 2025-04-09 | |
| Molecular and Genetic Studies of Congenital Myopathies Central Core Disease, Centronuclear Myopathy | Recruiting | Boston Children's Hospital | 4000 | 2003-08-01 | 2026-03-25 |
Myopathies, Structural, Congenital (12) · Myopathies, Nemaline (5) · Neuromuscular Diseases (5) · Muscular Diseases (4) · Myotonia Congenita (4) · Minicore Myopathy with External Ophthalmoplegia (3) · Musculoskeletal Diseases (3) · Myopathy, Central Core (3) · Charcot-Marie-Tooth Disease (2) · Muscular Dystrophy, Facioscapulohumeral (2) · Nervous System Diseases (2) · Amyotrophic Lateral Sclerosis (1) · Glycogen Storage Disease Type II (1) · Lambert-Eaton Myasthenic Syndrome (1) · Malignant Hyperthermia (1)
Nervous System Diseases (10) · Musculoskeletal Diseases (9) · Muscular Diseases (8) · Neuromuscular Diseases (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Heredodegenerative Disorders, Nervous System (6) · Neurodegenerative Diseases (6) · Myotonic Disorders (5) · Muscular Disorders, Atrophic (3) · Muscular Dystrophies (3) · Congenital Abnormalities (2) · Genetic Diseases, X-Linked (2) · Hereditary Sensory and Motor Neuropathy (2) · Nervous System Malformations (2)
Albuterol (1) · Dosage Forms (1) · Respiratory Rate (1) · Tablets (1)
Dynacure (3) · Boston Children's Hospital (1) · Centre Hospitalier Universitaire de Liege (1) · Institut de Myologie, France (1) · King's College London (1) · Newcastle-upon-Tyne Hospitals NHS Trust (1) · Radboud University Medical Center (1) · University of Erlangen-Nürnberg Medical School (1) · University of Missouri-Columbia (1) · Vastra Gotaland Region (1)
Germany (4) · Belgium (3) · France (3) · United Kingdom (3) · Netherlands (2) · United States (2) · Czechia (1) · Denmark (1) · Egypt (1) · Hungary (1) · Italy (1) · Poland (1) · Romania (1) · Slovenia (1) · Spain (1)
Alan H. Beggs, Ph.D. (1) · Chiara Marini Bettolo (1) · Chris Freitag, MD (1) · Ferdinand Knieling, PD Dr. med. habil. Dr. rer. b (1) · Laurent Servais, MD (1) · N.C. Voermans, MD, PhD (1) · Nicol Voermans, MD PhD (1) · Niklas Darin, M.D (1)
PMID 10051637, PMID 10192379, PMID 10508519, PMID 11558787, PMID 12196661, PMID 12601110, PMID 12677001, PMID 15056467, PMID 15236405, PMID 16042307, PMID 17160903, PMID 17537630, PMID 19232495, PMID 19346529, PMID 19562689, PMID 19944167, PMID 19953533, PMID 21357678, PMID 42551994
2019 (1)