8 unknown, 7 completed, 5 recruiting, 3 terminated. 11 Not applicable, 3 Phase 1, 3 Phase 2, 3 Phase 3, 1 Early Phase 1.
Follow Bladder Neoplasm: new trials by email Literature Review of Bladder Neoplasm trials Research Report on Bladder Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Imaging Study of [89Zr]DFO-YS5 for Cancer Detection [89Zr]DFO-YS5, Positron Emission Tomography (PET)-Computerized tomography (CT) - Bladder Cancer, Nerve Sheath Tumor | Phase 1 | Recruiting | Robert Flavell, MD, PhD | 40 | 2026-06-15 | 2026-10-01 |
| Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging - Bladder Cancer, Muscle-Invasive Bladder Carcinoma | Not applicable | Recruiting | Thomas Jefferson University | 70 | 2025-12-23 | 2026-02-17 |
| Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer multiparametric magnetic resonance imaging (mpMRI) of the bladder, Transurethral resection of bladder tumour (TURBt), Circulating tumour DNA levels assessment - Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Requiring Cystectomy | Phase 3 | Recruiting | University of Rome Tor Vergata | 92 | 2025-08-15 | 2025-07-24 |
| Virtuoso Improving Anatomic Bladder Lesion Excision (VIABLE) Trial The study is to evaluate the use of the Virtuoso Endoscopy System to perform safe and effective bladder lesion excisions. - Bladder Neoplasm | Not applicable | Enrolling by invitation | Virtuoso Surgical, Inc. | 30 | 2025-04-17 | 2026-06-29 |
| Bladder Preservation With Sacituzumab Govitecan + Zimberelimab for Muscle-Invasive Bladder Cancer Sacituzumab Govitecan + Zimberelimab - Bladder Cancer, Bladder Urothelial Carcinoma | Phase 2 | Not yet recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 63 | 2024-12-02 | 2024-07-30 |
| Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct) Daily Activity Goal and Feedback - Bladder Cancer, Bladder Neoplasm | Not applicable | Unknown | Universitätsmedizin Mannheim | 164 | 2023-03-14 | 2024-05-16 |
| Comparison of Interfascial Injection Versus Subpectineal Injection on Ultrasound-guided Obturator Nerve Block Interfascial Injection, Subpectineal Injection - Bladder Neoplasm | Not applicable | Completed | Diskapi Teaching and Research Hospital | 60 | 2022-09-16 | 2023-04-25 |
| Personalized Urine Biomarker for Patients With Bladder Cancer TURBT - Bladder Neoplasm | Unknown | Ziv Hospital | 20 | 2022-08-01 | 2022-07-20 | |
| Smurf2 Gene Expression in Urinary Tract Tumors immunohistochemistry of tumors samples - Bladder Neoplasm | Unknown | Ziv Hospital | 50 | 2021-12-01 | 2021-12-16 | |
| Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block pudendal nerve block - Bladder Neoplasm, Prostatic Neoplasms | Early Phase 1 | Unknown | Armed Forces Hospital, Pakistan | 250 | 2021-08-10 | 2021-08-26 |
| En Bloc TURBT With Collins Loop vs Conventional TURBT En bloc TURBT Collins Loop, Conventional TURBT - Bladder Cancer, Bladder Neoplasm | Not applicable | Unknown | Hospital Universitario de Fuenlabrada | 80 | 2021-04-01 | 2021-08-30 |
| Transurethral Modified En Bloc Resection For Large Bladder Tumours. Bipolar transurethral modified en bloc resection of bladder tumour - Bladder Cancer, Bladder Neoplasm | Not applicable | Completed | Chinese University of Hong Kong | 30 | 2020-09-07 | 2026-10-27 |
| En-Bloc Resection of Bladder Tumors En Bloc Resection, Conventional Transurethral Resection Bladder Tumor (Mono/Bipolar) - Bladder Neoplasm | Phase 2 | Unknown | Betul Kartal | 60 | 2020-04-01 | 2022-04-12 |
| A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma IK-175, IK-175 and nivolumab - Urothelial Carcinoma, Urothelial Carcinoma Bladder | Phase 1 | Completed | Ikena Oncology | 78 | 2019-12-18 | 2024-03-15 |
| Bipolar Versus Mono-polar Needlescopic En Bloc TUR-BT Bipolar En bloc TURBT, Monopolar En bloc TURBT - Bladder Cancer, Bladder Neoplasm | Not applicable | Unknown | Benha University | 200 | 2019-11-01 | 2022-07-19 |
| Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumors. Synergo® RITE + MMC - Bladder Cancer, Bladder Neoplasm | Phase 3 | Terminated | Medical Enterprises Ltd. | 5 | 2019-04-04 | 2020-04-15 |
| The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study Radiation therapy - Oncology, Breast Cancer | Recruiting | UMC Utrecht | 8000 | 2019-02-01 | 2026-03-05 | |
| Can VI-RADS/ADC Accurately Stage Bladder Cancer?? Multi-parametric MRI - MRI Contrast Media Adverse Reaction, Bladder Cancer | Not applicable | Active not recruiting | Mansoura University | 150 | 2019-01-01 | 2024-10-30 |
| The Potential Role Of MicroRNA-155 And Telomerase Reverse Transcriptase In Diagnosis Of Non-Muscle Invasive Bladder Cancer And Their Pathological Correlation MicroRNAs-155, Human telomerase reverse transcriptase - Bladder Cancer, Bladder Disease | Not applicable | Completed | Mansoura University | 115 | 2018-08-01 | 2019-11-04 |
| Pre-Operative Single Shot Rectus Sheath Block Rectus sheath block, Bilateral rectus sheath catheter, Patient controlled opioid analgesia (PCA) - Bladder Neoplasm, Prostate Neoplasm | Not applicable | Completed | University of Alberta | 49 | 2018-02-16 | 2022-07-28 |
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Urinary Bladder Neoplasms (26) · Carcinoma, Transitional Cell (5) · Urinary Bladder Diseases (5) · Neoplasms (4) · Non-Muscle Invasive Bladder Neoplasms (3) · Prostatic Neoplasms (3) · Urologic Neoplasms (3) · Breast Neoplasms (2) · Neoplasm Metastasis (2) · Pancreatic Neoplasms (2) · Recurrence (2) · Urogenital Neoplasms (2) · Brain Neoplasms (1) · Carcinoma (1) · Carcinoma in Situ (1)
Female Urogenital Diseases (26) · Female Urogenital Diseases and Pregnancy Complications (26) · Male Urogenital Diseases (26) · Urogenital Diseases (26) · Neoplasms by Site (25) · Urologic Diseases (25) · Urogenital Neoplasms (24) · Urologic Neoplasms (23) · Neoplasms (22) · Urinary Bladder Diseases (21) · Neoplasms by Histologic Type (9) · Neoplasms, Glandular and Epithelial (8) · Carcinoma (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7)
Mitomycin (2) · 10-propargyl-10-deazaaminopterin (1) · Folic Acid (1) · MLN8054 (1) · Magnetic Resonance Spectroscopy (1) · Multiparametric Magnetic Resonance Imaging (1) · Nivolumab (1) · Optical Imaging (1) · Radiotherapy (1) · Transurethral Resection of Bladder (1) · Vitamin B 12 (1) · sacituzumab govitecan (1) · zimberelimab (1)
Mansoura University (3) · Ziv Hospital (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Acrotech Biopharma Inc. (1) · Armed Forces Hospital, Pakistan (1) · Benha University (1) · Betul Kartal (1) · Bioniche Life Sciences Inc. (1) · Chinese University of Hong Kong (1) · Diskapi Teaching and Research Hospital (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · Hospital Universitario de Fuenlabrada (1) · IRCCS San Raffaele (1) · Ikena Oncology (1) · Medical Enterprises Ltd. (1)
United States (8) · Egypt (4) · Italy (4) · Canada (3) · Germany (3) · Netherlands (3) · Belgium (2) · Hong Kong (2) · Spain (2) · Turkey (Türkiye) (2) · United Kingdom (2) · Argentina (1) · Australia (1) · Croatia (1) · Denmark (1)
Ahmed Mosbah, MD (2) · Abdelwahab Hashem, Msc (1) · Ahmed Elshal, MD (1) · Ahmed Mosbah, MD, Phd (1) · Bedir Ali-Eldeen, MD, Phd (1) · Francesco Montorsi, MD (1) · Garry Weems, Pharm.D. (1) · Giuseppe Procopio, MD (1) · Helena M Verkooijen, Prof, Dr (1) · Jeremy Teoh (1) · Jeremy YC Teoh, MBBS (1) · Karim Malek, MD (1) · Karl-Friedrich Kowalewski, PD Dr. med (1) · Michael A O'Donnell, MD (1)
PMID 29415874, PMID 33014774, PMID 34981300, PMID 41276423, PMID 41506574