2 recruiting, 1 active not recruiting, 1 completed, 1 unknown. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Recruiting 2, Active not recruiting 1, Completed 1, Unknown 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow ALL, Childhood: new trials by email Literature Review of ALL, Childhood trials Research Report on ALL, Childhood
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies Fludarabine, Cyclophosphamide, CD70-CAR T cell infusion (Autologous) - Hematologic Malignancy, ALL, Childhood | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 18 | 2024-10-16 | 2026-01-23 |
| Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies KUR-502 - NHL, Relapsed, Adult, B-cell Lymphoma | Phase 1 | Unknown | Athenex, Inc. | 36 | 2022-10-01 | 2023-05-18 |
| Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia Ruxolitinib, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia, ALL, Childhood | Phase 1 | Recruiting | University of Chicago | 15 | 2019-05-28 | 2026-06-29 |
| PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Ixazomib, Vincristine, Dexamethasone - ALL, Childhood, Lymphoblastic Lymphoma, Childhood | Phase 1 / Phase 2 | Active not recruiting | Therapeutic Advances in Childhood Leukemia Consortium | 24 | 2019-02-12 | 2025-06-17 |
| Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy Marqibo - ALL, Childhood, Lymphoblastic Leukemia, Acute, Childhood | Phase 1 | Completed | Therapeutic Advances in Childhood Leukemia Consortium | 29 | 2017-01-31 | 2025-10-22 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Dendritic Cell Sarcoma, Interdigitating (1) · Hematologic Neoplasms (1) · Leukemia, B-Cell (1) · Leukemia, Myeloid, Acute (1) · Lymphoma (1) · Lymphoma, B-Cell (1) · Lymphoma, Non-Hodgkin (1) · Recurrence (1)
Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Leukemia (5) · Leukemia, Lymphoid (5) · Lymphatic Diseases (5) · Lymphoproliferative Disorders (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Disease Attributes (1) · Histiocytic Disorders, Malignant (1) · Histiocytosis (1) · Leukemia, Myeloid (1) · Lymphoma (1)
Vincristine (3) · Cyclophosphamide (2) · Cytarabine (2) · Dexamethasone (2) · Doxorubicin (2) · Methotrexate (2) · Administration, Intravenous (1) · Asparaginase (1) · Hydrocortisone (1) · Leucovorin (1) · Mercaptopurine (1) · Mesna (1) · Rituximab (1) · Thioguanine (1) · fludarabine (1)
Therapeutic Advances in Childhood Leukemia Consortium (2) · Athenex, Inc. (1) · St. Jude Children's Research Hospital (1) · University of Chicago (1)
United States (5) · Australia (2) · Canada (1)
Carlos Ramos, MD (1) · Swati Naik, MBBS (1) · Terzah Horton, MD (1) · Wendy Stock, MD (1)