3 completed, 2 active not recruiting, 2 terminated, 1 recruiting. 8 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 3, Active not recruiting 2, Terminated 2, Recruiting 1 |
Follow Advanced Breast Carcinoma: new trials by email Literature Review of Advanced Breast Carcinoma trials Research Report on Advanced Breast Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax Atezolizumab, Cabozantinib S-malate, Nab-paclitaxel - Advanced Breast Carcinoma, Advanced Endometrial Carcinoma | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 43 | 2022-04-29 | 2026-07-16 |
| Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer Cisplatin, Elimusertib, Gemcitabine Hydrochloride - Advanced Bile Duct Carcinoma, Advanced Breast Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 74 | 2021-08-25 | 2026-07-31 |
| Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial Biopsy Procedure, Biospecimen Collection, Ceralasertib - Advanced Breast Carcinoma, Advanced Colon Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 51 | 2021-08-09 | 2026-09-04 |
| Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors NUV-422 - Glioma, Glioma, Malignant | Phase 1 | Terminated | Nuvation Bio Inc. | 74 | 2020-12-08 | 2023-07-14 |
| Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer Alpelisib, Enzalutamide - Advanced Breast Carcinoma, Anatomic Stage III Breast Cancer AJCC v8 | Phase 1 | Completed | M.D. Anderson Cancer Center | 18 | 2019-06-07 | 2024-10-10 |
| PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery Docetaxel, Laboratory Biomarker Analysis, Pharmacological Study - Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 23 | 2018-09-24 | 2026-04-29 |
| Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer Laboratory Biomarker Analysis, Onalespib, Paclitaxel - Advanced Breast Carcinoma, Metastatic Breast Carcinoma | Phase 1 | Terminated | National Cancer Institute (NCI) | 31 | 2016-01-15 | 2022-11-04 |
| Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer ONT-10, Varlilumab combination - Advanced Breast Carcinoma, Advanced Ovarian Carcinoma | Phase 1 | Completed | Cascadian Therapeutics Inc. | 22 | 2014-11-01 | 2018-05-17 |
Breast Neoplasms (6) · Triple Negative Breast Neoplasms (4) · Endometrial Neoplasms (2) · Neoplasm Metastasis (2) · Ovarian Neoplasms (2) · Prostatic Neoplasms (2) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Carcinosarcoma (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Fallopian Tube Neoplasms (1) · Glioblastoma (1) · Glioma (1) · Lung Neoplasms (1)
Breast Diseases (7) · Neoplasms (7) · Neoplasms by Site (7) · Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Genital Diseases (5) · Urogenital Diseases (5) · Urogenital Neoplasms (5) · Male Urogenital Diseases (4) · Neoplasms by Histologic Type (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases, Female (3) · Genital Diseases, Male (3) · Genital Neoplasms, Female (3)
Taxes (2) · (2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone (1) · 1,2-diaminocyclohexaneplatinum II citrate (1) · 130-nm albumin-bound paclitaxel (1) · AZD8186 (1) · Albumin-Bound Paclitaxel (1) · Alpelisib (1) · BAY 1895344 (1) · Biopsy (1) · Cisplatin (1) · Docetaxel (1) · Gemcitabine (1) · Magnetic Resonance Spectroscopy (1) · Paclitaxel (1) · Platinum (1)
National Cancer Institute (NCI) (4) · M.D. Anderson Cancer Center (2) · Cascadian Therapeutics Inc. (1) · Nuvation Bio Inc. (1)
United States (8) · Canada (1)
Alison M Schram (1) · Apostolia M Tsimberidou (1) · Kanwal P Raghav (1) · Mamta Parikh (1) · Meghan Karuturi (1) · Robert Wesolowski (1)
PMID 36351402, PMID 38152697, PMID 40939237
UM1CA186688 (1), UM1CA186691 (1), UM1CA186712 (1), UM1CA186717 (1)