2 completed, 1 unknown. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 1 | Unknown 1 |
Follow AZD8186: new trials by email Literature Review of AZD8186 trials Research Report on AZD8186
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AZD8186 and Paclitaxel in Advanced Gastric Cancer AZD8186 in combination with paclitaxel - Solid Tumor, Stomach Cancer | Phase 1 / Phase 2 | Unknown | Seoul National University Bundang Hospital | 49 | 2019-05-14 | 2019-06-28 |
| PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery Docetaxel, Laboratory Biomarker Analysis, Pharmacological Study - Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 23 | 2018-09-24 | 2026-04-29 |
| AZD8186 First Time In Patient Ascending Dose Study Part A: AZD8186 monotherapy, Part B: AZD8186 monotherapy, Part C1: Abiraterone acetate combination with AZD8186 - Advanced Castrate-resistant Prostate Cancer CRPC, Squamous Non-Small Cell Lung Cancer sqNSCLC | Phase 1 | Completed | AstraZeneca | 147 | 2013-07-09 | 2020-05-29 |
Triple Negative Breast Neoplasms (2) · Breast Neoplasms (1) · Neoplasm Metastasis (1) · Prostatic Neoplasms (1) · Stomach Neoplasms (1)
AstraZeneca (1) · National Cancer Institute (NCI) (1) · Seoul National University Bundang Hospital (1)
United States (2) · Canada (1) · South Korea (1) · Spain (1) · United Kingdom (1)
Alison M Schram (1) · Keun-Wook Lee, MD. & Ph.D (1) · Lillian Siu, MD (1) · Michele Mochetta, MD (1)
PMID 36351402, PMID 37036671, PMID 40939237
UM1CA186691 (1)