8 recruiting, 4 not yet recruiting, 2 active not recruiting, 2 completed. 5 Phase 2, 4 Not applicable, 4 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Recruiting 3, Completed 2 |
| Not applicable | 4 | Not yet recruiting 2, Recruiting 2 |
| Phase 1 | 4 | Completed 2, Active not recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 2 |
Follow Acute Lymphoblastic Leukemia ALL: new trials by email Literature Review of Acute Lymphoblastic Leukemia ALL trials Research Report on Acute Lymphoblastic Leukemia ALL
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect. 4A10 - Lymphoblastic Lymphoma, Acute Lymphoblastic Leukemia ALL | Phase 1 | Recruiting | Allterum Therapeutics, Inc | 24 | 2026-06-01 | 2026-09-01 |
| Role of T Lymphocytes in Hypersensitivity Reactions to Asparaginase in Patients Treated for Acute Lymphoblastic Leukemia. Asparaginase-induced in vitro T-cell stimulation - Acute Lymphoblastic Leukemia ALL | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 20 | 2026-04-30 | 2026-04-14 |
| Study of Cell-free DNA in Children and Adolescents With Acute Lymphoblastic Leukemia Biological sample collection - Acute Lymphoblastic Leukemia ALL | Recruiting | Assistance Publique - Hôpitaux de Paris | 205 | 2026-04-24 | 2026-08-26 | |
| Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy. Laughter and Fun Yoga Program - Acute Lymphoblastic Leukemia ALL | Not applicable | Recruiting | Bahaa Bou Dargham | 60 | 2025-10-15 | 2026-01-08 |
| Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia Acute Lymphoblastic Leukemia ALL, Chronic Lymphocytic Leukemia (CLL) | Not yet recruiting | Safaa Ali | 84 | 2025-08-01 | 2025-08-08 | |
| Online Physical Activity and Health Counseling for Survivors of Childhood Acute Lymphoblastic Leukemia Exercise - Acute Lymphoblastic Leukemia ALL, Childhood Cancer Survivors | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 82 | 2025-07-01 | 2025-06-29 |
| Tracjectories and Predictors of Chemotherapy Induced Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia Acute Lymphoblastic Leukemia ALL | Recruiting | The Hong Kong Polytechnic University | 173 | 2025-06-02 | 2026-01-08 | |
| Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol Blinatumomab, Reinduction-2 omission, Chemo-light Maintenance 2 - Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic | Phase 2 / Phase 3 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 3000 | 2025-03-03 | 2025-08-26 |
| Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia total marrow/lymphoid irradiation - Acute Myeloid Leukaemia (AML), Acute Lymphoblastic Leukemia ALL | Not applicable | Recruiting | University Of Perugia | 51 | 2025-02-25 | 2025-03-04 |
| An Extension Study to Evaluate the Safety and Efficacy of an Anti-CD19 CAR-T Product in Patients with B-cell Lymphoproliferative Disorders Non-Hodgkin Lymphoma, B-cell, Acute Lymphoblastic Leukemia ALL | Not yet recruiting | National Research Center for Hematology, Russia | 60 | 2025-01-09 | 2024-12-06 | |
| Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol Blinatumomab (Group A), Venetoclax (nonRand Group), Blinatumomab (Group B) - Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic | Phase 2 / Phase 3 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 1800 | 2025-01-03 | 2026-07-23 |
| A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders Hem101 - Non-Hodgkin Lymphoma, B-cell, Acute Lymphoblastic Leukemia ALL | Phase 1 / Phase 2 | Completed | National Research Center for Hematology, Russia | 58 | 2024-11-26 | 2026-02-09 |
| Autologous Hematopoietic Stem Cell Transplantation Combined With CD19-CART Treatment of Adult High-risk Acute Lymphoblastic Leukemia Autologous hematopoietic stem cell transplantation combined with CD19-CART - Acute Lymphoblastic Leukemia ALL | Phase 2 | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 20 | 2024-06-25 | 2024-09-23 |
| Psychiatric Problems in Children With Acute Lymphoblastic Leukemia and Their Caregivers Child Behavioral Checklist (CBCL):is a checklist parents complete to detect emotional and behavioral problems in children and adolescent, it consists of 113 questions for both groups., parent report on child's responses to stress (PCT):is a questionnaire which is used to obtain mothers' and fathers' reports of their children's coping with cancer, Symptom Checklist -90- Revised (SCL-90-R) for parents - Acute Lymphoblastic Leukemia ALL | Active not recruiting | Assiut University | 90 | 2024-06-01 | 2024-12-09 | |
| Safety and Preliminary Efficacy of Donor-derived Anti-leukemia Cytotoxic T Lymphocytes for the Prevention of Leukemia Relapse in Children Given Haploidentical Hematopoietic Stem Cell Transplantation HSCT donor leukemia-specific cytotoxic T-cells - Acute Lymphoblastic Leukemia ALL, Acute Myeloid Leukemia (AML) | Phase 1 / Phase 2 | Completed | Fondazione IRCCS Policlinico San Matteo di Pavia | 15 | 2021-02-13 | 2025-03-07 |
| Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL Ribociclib, Dexamethasone, Everolimus - Acute Lymphoblastic Leukemia ALL | Phase 1 | Active not recruiting | Dana-Farber Cancer Institute | 45 | 2019-01-30 | 2026-08-21 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (16) · Burkitt Lymphoma (2) · Leukemia, Myeloid, Acute (2) · Lymphoma, B-Cell (2) · Lymphoma, Non-Hodgkin (2) · Recurrence (2) · Agnosia (1) · Cancer Pain (1) · Leukemia (1) · Leukemia, B-Cell (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Motor Activity (1) · Neoplasm, Residual (1)
Hematologic Diseases (16) · Hemic and Lymphatic Diseases (16) · Immune System Diseases (16) · Immunoproliferative Disorders (16) · Leukemia, Lymphoid (16) · Lymphatic Diseases (16) · Lymphoproliferative Disorders (16) · Neoplasms (16) · Neoplasms by Histologic Type (16) · Leukemia (15) · Pathological Conditions, Signs and Symptoms (5) · Lymphoma (4) · Pathologic Processes (4) · Disease Attributes (3) · DNA Virus Infections (2)
Dexamethasone (3) · Methotrexate (2) · Vincristine (2) · blinatumomab (2) · Asparaginase (1) · Cyclophosphamide (1) · Cytarabine (1) · Daunorubicin (1) · Everolimus (1) · Exercise (1) · Lymphatic Irradiation (1) · Prednisone (1) · ribociclib (1) · venetoclax (1)
Institute of Hematology & Blood Diseases Hospital, China (3) · National Research Center for Hematology, Russia (2) · Allterum Therapeutics, Inc (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Bahaa Bou Dargham (1) · Centre Hospitalier Universitaire de Nice (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dana-Farber Cancer Institute (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Safaa Ali (1) · The Hong Kong Polytechnic University (1) · University Of Perugia (1)
China (4) · France (2) · Hong Kong (2) · Italy (2) · Russia (2) · United States (2) · Egypt (1) · Lebanon (1)
Xiaofan Zhu, MD (2) · Andrew E Place, MD, PhD (1) · Bahaa W Bou Dargham, MD (1) · Eric Schafer, MD (1) · Hebatallah Abdellatif, asst. prof (1) · Ka Yan Ho (1) · Martin K Fridh, Ph.D (1)
R44CA268530 (1)