2 completed, 1 active not recruiting, 1 recruiting. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
Follow Acute Lymphoblastic Leukemia ALL: new trials by email Literature Review of Acute Lymphoblastic Leukemia ALL trials Research Report on Acute Lymphoblastic Leukemia ALL
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect. 4A10 - Lymphoblastic Lymphoma, Acute Lymphoblastic Leukemia ALL | Phase 1 | Recruiting | Allterum Therapeutics, Inc | 24 | 2026-06-01 | 2026-09-01 |
| A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders Hem101 - Non-Hodgkin Lymphoma, B-cell, Acute Lymphoblastic Leukemia ALL | Phase 1 / Phase 2 | Completed | National Research Center for Hematology, Russia | 58 | 2024-11-26 | 2026-02-09 |
| Safety and Preliminary Efficacy of Donor-derived Anti-leukemia Cytotoxic T Lymphocytes for the Prevention of Leukemia Relapse in Children Given Haploidentical Hematopoietic Stem Cell Transplantation HSCT donor leukemia-specific cytotoxic T-cells - Acute Lymphoblastic Leukemia ALL, Acute Myeloid Leukemia (AML) | Phase 1 / Phase 2 | Completed | Fondazione IRCCS Policlinico San Matteo di Pavia | 15 | 2021-02-13 | 2025-03-07 |
| Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL Ribociclib, Dexamethasone, Everolimus - Acute Lymphoblastic Leukemia ALL | Phase 1 | Active not recruiting | Dana-Farber Cancer Institute | 45 | 2019-01-30 | 2026-08-21 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Leukemia (1) · Leukemia, Myeloid, Acute (1) · Lymphoma, B-Cell (1) · Lymphoma, Non-Hodgkin (1) · Recurrence (1)
Hematologic Diseases (4) · Hemic and Lymphatic Diseases (4) · Immune System Diseases (4) · Immunoproliferative Disorders (4) · Leukemia, Lymphoid (4) · Lymphatic Diseases (4) · Lymphoproliferative Disorders (4) · Neoplasms (4) · Neoplasms by Histologic Type (4) · Leukemia (3) · Disease Attributes (1) · Leukemia, Myeloid (1) · Lymphoma (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Dexamethasone (1) · Everolimus (1) · ribociclib (1)
Allterum Therapeutics, Inc (1) · Dana-Farber Cancer Institute (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · National Research Center for Hematology, Russia (1)
United States (2) · Italy (1) · Russia (1)
Andrew E Place, MD, PhD (1) · Eric Schafer, MD (1)
R44CA268530 (1)