3 recruiting, 2 not yet recruiting, 2 unknown, 1 completed. 4 Phase 2, 3 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Not yet recruiting 2, Completed 1, Recruiting 1 |
| Not applicable | 3 | Unknown 2, Recruiting 1 |
| Phase 1 | 2 | Recruiting 1, Suspended 1 |
Follow Lymphatic Irradiation: new trials by email Literature Review of Lymphatic Irradiation trials Research Report on Lymphatic Irradiation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Acute Myeloid Leukemia With Complex Karyotype, Myelodysplastic Chronic Myelomonocytic Leukemia | Phase 2 | Recruiting | City of Hope Medical Center | 35 | 2026-11-05 | 2026-10-08 |
| Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell Transplant VMAT-Based Total Marrow and Lymphoid Irradiation (TMLI), Fludarabine, Cyclophosphamide - Acute Myeloid Leukemia, Myeloproliferative Neoplasm | Phase 2 | Not yet recruiting | Stanford University | 30 | 2026-11-01 | 2026-09-30 |
| 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome Actinium Ac 225-DOTA-Daratumumab, Biospecimen Collection, Bone Marrow Aspiration - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 | Recruiting | City of Hope Medical Center | 15 | 2025-07-01 | 2026-07-31 |
| Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia total marrow/lymphoid irradiation - Acute Myeloid Leukaemia (AML), Acute Lymphoblastic Leukemia ALL | Not applicable | Recruiting | University Of Perugia | 51 | 2025-02-25 | 2025-03-04 |
| TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Total bone marrow and lymphoid irradiation/cyclophosphamide/etoposide - Myelodysplastic Syndromes, Myeloid Leukemia, Acute | Phase 2 | Not yet recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 58 | 2024-12-30 | 2024-09-19 |
| Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 1 | Suspended | City of Hope Medical Center | 33 | 2024-05-24 | 2026-10-15 |
| Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute Leukemia total body irradiation, total marrow and lymphoid irradiation - Acute Leukemia | Not applicable | Unknown | Affiliated Hospital to Academy of Military Medical Sciences | 100 | 2014-03-01 | 2018-01-23 |
| Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute Leukemia total body irradiation, total marrow and lymphoid irradiation - Myelodysplastic Syndromes, Acute Leukemia | Not applicable | Unknown | Affiliated Hospital to Academy of Military Medical Sciences | 191 | 2014-03-01 | 2018-01-23 |
| Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma anti-thymocyte globulin, cyclosporine, Lymphoid radiation - Mycoses, Sezary Syndrome | Phase 2 | Completed | Stanford University | 38 | 2009-05-01 | 2023-05-11 |
Leukemia, Myeloid, Acute (6) · Myelodysplastic Syndromes (6) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Lymphoma, Non-Hodgkin (1) · Lymphoma, T-Cell, Cutaneous (1) · Mycoses (1) · Myeloproliferative Disorders (1) · Recurrence (1) · Sezary Syndrome (1)
City of Hope Medical Center (3) · Affiliated Hospital to Academy of Military Medical Sciences (2) · Stanford University (2) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · University Of Perugia (1)
United States (5) · China (2) · Italy (1) · Spain (1)
Hu Chen, M.D., Ph.D. (2) · Amandeep Salhotra (1) · Hany Elmariah, MD (1) · Jeffrey Y Wong (1) · Monzr M Al Malki (1) · Wen-Kai Weng (1)
P30CA033572 (3)