35 completed, 15 recruiting, 8 terminated, 6 not yet recruiting. 71 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 71 | Completed 35, Recruiting 15, Terminated 8, Not yet recruiting 6, Active not recruiting 3, Unknown 2, Suspended 1, Withdrawn 1 |
Follow Acute Lymphoblastic Leukemia: new trials by email Literature Review of Acute Lymphoblastic Leukemia trials Research Report on Acute Lymphoblastic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 2 Gy Total Body Irradiation As Part Of Conditioning Treatment For Patients With Acute Lymphoblastic Leukemia Undergoing CAR T Cell Therapy CAR T cell therapy - Acute Lymphoblastic Leukemia | Not applicable | Not yet recruiting | M.D. Anderson Cancer Center | 20 | 2027-03-01 | 2026-10-05 |
| Prevention of Oral Mucositis in Adults in With Hematologic Malignancy Aloe Vera Mouthwash, Standard of Care - Acute Leukemia, Acute Myeloid Leukemia | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 206 | 2027-01-01 | 2026-10-22 |
| Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies Ossium HPC, Marrow, Standard of care living donor - Haplo Related, Standard of care living donor - Mismatched Unrelated - Hematologic Malignancy, Acute Leukemia | Not applicable | Not yet recruiting | Ossium Health, Inc. | 300 | 2026-12-01 | 2026-09-10 |
| Digital Patient-Reported Assessment in Older Adults With Acute Leukemia Digital Patient-Reported Assessment Pathway - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia | Not applicable | Not yet recruiting | Fundación para la Investigación Biosanitaria del Principado de Asturias | 20 | 2026-12-01 | 2026-10-07 |
| A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph... NGS testing - B-All, Acute Lymphoblastic Leukemia | Not applicable | Recruiting | National Cancer Institute (NCI) | 60 | 2026-11-05 | 2026-11-02 |
| A Single-center, Prospective, Exploratory Clinical Study Lisaftoclax - Acute Lymphoblastic Leukemia | Not applicable | Not yet recruiting | LanZhou University | 30 | 2026-08-01 | 2026-08-31 |
| ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL Olverembatinib, Gecacitinib, Venetoclax - Ph-Like, Acute Lymphoblastic Leukemia | Not applicable | Recruiting | Institute of Hematology & Blood Diseases Hospital, China | 92 | 2026-05-30 | 2026-05-13 |
| Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia High Intensity, No Text Messagings, Low Intensity Text Messaging - Acute Lymphoblastic Leukemia, T-cell Lymphoblastic Lymphoma | Not applicable | Recruiting | University of Chicago | 48 | 2026-05-19 | 2026-07-10 |
| Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL) Exercises - Leukemia, Acute Leukemia | Not applicable | Recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2026-05-01 | 2026-08-03 |
| Treatment for Ph-negative ALL for Adults up to 65 Years Pediatric-type of chemotherapy (+blinatumomab for B-cell precursor ALL), Transplantation - Acute Lymphoblastic Leukemia | Not applicable | Not yet recruiting | PETHEMA Foundation | 330 | 2026-03-06 | 2026-03-02 |
| Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes Exercise - Sarcopenia, Acute Lymphoblastic Leukemia | Not applicable | Recruiting | Murdoch Childrens Research Institute | 60 | 2026-02-24 | 2026-07-06 |
| MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia MB-CART19.1 - Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia Recurrent | Not applicable | Recruiting | King Hussein Cancer Center | 12 | 2026-02-20 | 2026-08-05 |
| Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Allogeneic Transplant or Chemotherapy Digital cognitive training, Online Mindfulness-Based Intervention - Acute Lymphoblastic Leukemia | Not applicable | Recruiting | Hospital Universitario La Paz | 40 | 2025-12-19 | 2026-03-18 |
| The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment mandala painting - Acute Lymphoblastic Leukemia, Childhood Acute Leukemia | Not applicable | Recruiting | Ege University | 60 | 2025-09-29 | 2026-02-17 |
| Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia ADAPTS (ADherence Assessments and Personalized Timely Support). - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Not applicable | Recruiting | Northwestern University | 60 | 2025-07-31 | 2026-06-30 |
| TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant CliniMACS® device - Graft Vs Host Disease, Graft-versus-host-disease | Not applicable | Withdrawn | Neena Kapoor, M.D. | 2025-05-27 | 2025-07-14 | |
| MedSupport Intervention to Identify and Address Barriers to Pediatric Medication Adherence Best Practice, Biospecimen Collection, Electronic Health Record Review - Acute Lymphoblastic Leukemia | Not applicable | Recruiting | Roswell Park Cancer Institute | 150 | 2025-02-11 | 2026-08-12 |
| Effects of Core Stabilization Exercises in Children With Acute Lymphoblastic Leukemia Conventional exercises, Core stabilization exercises in addition to conventional exercises - Acute Lymphoblastic Leukemia | Not applicable | Completed | Karamanoğlu Mehmetbey University | 27 | 2025-01-14 | 2026-10-07 |
| A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home Biospecimen Collection, Compliance Monitoring, Health Promotion and Education - Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia | Not applicable | Suspended | Children's Oncology Group | 64 | 2024-12-04 | 2026-10-05 |
| A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors PEDALL, Standard of care - Acute Lymphoblastic Leukemia, Obesity | Not applicable | Recruiting | Columbia University | 376 | 2024-03-19 | 2025-10-07 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (71) · Leukemia, Myeloid, Acute (21) · Myelodysplastic Syndromes (10) · Hodgkin Disease (9) · Lymphoma, Non-Hodgkin (8) · Neoplasms (8) · Leukemia (7) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (7) · Motor Activity (6) · Multiple Myeloma (5) · Hematologic Neoplasms (4) · Lymphoma (4) · Myeloproliferative Disorders (3) · Obesity (3) · Anemia, Aplastic (2)
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PMID 22609885, PMID 24436138, PMID 25030039, PMID 27445347, PMID 27760758, PMID 27798515, PMID 27922922, PMID 30176891, PMID 30861163, PMID 35777413, PMID 38062808, PMID 38102639, PMID 38559896, PMID 39985582, PMID 40488780, PMID 42081455, PMID 42263667
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