12 unknown, 8 recruiting, 1 completed. 11 Early Phase 1, 6 Phase 1, 3 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 11 | Recruiting 6, Unknown 5 |
| Phase 1 | 6 | Unknown 4, Recruiting 2 |
| Phase 2 | 3 | Unknown 2, Recruiting 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Antibody-armored Dendritic Cell in Patients With Solid Tumors Armored Dendritic Cell Injection - Solid Cancers, Adjuvant Therapy | Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 8 | 2026-02-05 | 2026-03-18 |
| An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases CD19/CD22/BCMA CAR-T cells(BZE2204) - Idiopathic Inflammatory Myopathies(IIM), Immune Thrombocytopenia(ITP) | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 20 | 2025-09-01 | 2025-09-16 |
| Exploratory Study of Super DC Cell Injection in Preventing Recurrence After Radical Surgery for Tumors Super DC Vaccine - Solid Tumor Cancer | Phase 1 / Phase 2 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 12 | 2025-07-31 | 2025-08-28 |
| An Exploratory Study of Chenghuang Circadian Rhythm Regulator in Subjects With Sleep Disorders Chenghuang Circadian Rhythm Regulator - Sleep Disorders | Not applicable | Completed | Shanghai Cell Therapy Group Co.,Ltd | 15 | 2025-06-06 | 2026-02-17 |
| A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma CD19/CD20/BCMA CAR-T - Relapsed, Refractory | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 12 | 2024-12-12 | 2024-12-13 |
| A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL) CD19/CD20/BCMA CAR T cells - Non-Hodgkin Lymphoma, B-cell | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 20 | 2024-05-07 | 2025-08-21 |
| An Exploratory Study by Fast CAR T Cells Fast CAR T cells - Solid Tumor | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 20 | 2024-03-07 | 2024-03-25 |
| The Exploratory Study About the Effect of Using Double Filtration Plasmapheresis (DFPP) Removing Inflammatory Cytokines, Lipids and Toxic Metal Ions in Peripheral Blood in Adults DFPP - Sub-healthy, Hyperlipidemia | Not applicable | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 250 | 2024-03-01 | 2024-01-25 |
| The Exploratory Study on the Biological Function of Dendritic Cells In Vivo Supported by Nicotinamide Mononucleotide (Vital NAD) Oral NMN combined with DC cell vaccine - Postoperative Prevention of Tumor | Early Phase 1 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 20 | 2023-09-30 | 2023-09-13 |
| Phase I/II Study of αPD1-MSLN-CAR T Cells in MSLN-positive Advanced Solid Tumors αPD1-MSLN-CAR T Cells - Advanced Solid Tumor | Phase 1 / Phase 2 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 42 | 2023-09-01 | 2023-07-14 |
| The Exploratory Study on the Nicotinamide Mononucleotide (Vital NAD ) to Promote the Rejuvenation of the Peripheral Blood Immune Cells of Adults. NMN - Enhance Immune Function | Early Phase 1 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 10 | 2023-08-01 | 2023-08-21 |
| The Exploratory Study on the Baseline Level of NAD+/NADH in Peripheral Blood Samples of Different Gender and Age Groups of Healthy Adults. Detection of NAD+/NADH concentration of Peripheral Blood Samples - NAD+/NADH in Peripheral Blood Monitoring | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 60 | 2023-08-01 | 2023-08-18 | |
| Exploratory Study on Baize DC Injection in Preventing Recurrence and Metastasis After Radical Tumor Surgery DC cells - Solid Tumor | Phase 1 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 200 | 2023-08-01 | 2023-08-29 |
| An Exploratory Study on the Treatment of Advanced Solid Tumors by Fast CAR T Cells Fast CAR T cells - Solid Tumor | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 12 | 2023-06-01 | 2024-02-08 |
| Exploratory Study of MSLN-CAR T Cells Secreting PD1/CTLA-4 Nanoantibody for the Treatment of Advanced Solid Tumors αPD1/CTLA4-MSLN-CAR T cells - Solid Tumor | Early Phase 1 | Recruiting | Shanghai Cell Therapy Group Co.,Ltd | 16 | 2023-01-01 | 2024-02-08 |
| Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors CAR T cells - Colorectal Cancer | Phase 1 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 30 | 2021-11-30 | 2023-07-17 |
| Study of Efficacy of BZ019 in Large B-cell Lymphoma BZ019 - Large B-cell Lymphoma | Phase 2 | Unknown | Shanghai Mengchao Cancer Hospital | 36 | 2021-06-04 | 2022-07-25 |
| αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors αPD1-MSLN-CAR T cells - Solid Tumor | Early Phase 1 | Unknown | Shanghai Mengchao Cancer Hospital | 21 | 2020-10-30 | 2022-10-26 |
| αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors αPD1-MSLN-CAR T cells - Non-small-cell Lung Cancer, Mesothelioma | Early Phase 1 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 10 | 2020-05-13 | 2020-07-28 |
| αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors αPD1-MSLN-CAR T cells - Colorectal Cancer, Ovarian Cancer | Early Phase 1 | Unknown | Shanghai Cell Therapy Group Co.,Ltd | 10 | 2020-03-26 | 2020-08-07 |
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Colorectal Neoplasms (2) · Autoimmune Diseases (1) · Carcinoma, Non-Small-Cell Lung (1) · Hyperlipidemias (1) · Lupus Erythematosus, Systemic (1) · Lymphoma, B-Cell (1) · Lymphoma, Non-Hodgkin (1) · Mesothelioma (1) · Multiple Myeloma (1) · Myositis (1) · Ovarian Neoplasms (1) · Purpura, Thrombocytopenic, Idiopathic (1) · Recurrence (1) · Sleep Wake Disorders (1)
Immunotherapy, Adoptive (1) · Nicotinamide Mononucleotide (1)
China (21)
Jinxing Lou (5) · Jianchun Duan (1) · Lugui Qiu, Ph.D (1) · Qing Qu (1) · Xiaorong Dong (1) · Zhicai Lin (1)