2 completed, 2 unknown, 1 recruiting. 5 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 2, Unknown 2, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Dotinurad in Hyperuricemia With Hypertension Dotinurad, Febuxostat - Hyperuricemia or Gout, Hypertension | Phase 4 | Recruiting | Saga University | 360 | 2025-03-28 | 2025-12-15 |
| Effects of Finerenone on Vascular Stiffness and Cardiorenal Biomarkers in T2D and CKD (FIVE-STAR) Finerenone, Placebo - Type 2 Diabetes, Chronic Kidney Diseases | Phase 4 | Unknown | Saga University | 100 | 2023-09-07 | 2024-02-07 |
| Program of Angiotensin-Neprilysin Inhibition in Admitted Patients With Worsening Heart Failure (PREMIER) Sacubitril Valsartan Sodium Hydrate, Standard treatment - Heart Failure | Phase 4 | Unknown | Saga University | 400 | 2021-12-27 | 2024-08-21 |
| GRam Stain-guided Antibiotics ChoicE for Ventilator-Associated Pneumonia (GRACE-VAP) Trial Gram stain-guided antibiotic choice, Guidelines-based antibiotics choice - Ventilator Associated Pneumonia | Phase 4 | Completed | Osaka General Medical Center | 206 | 2018-04-01 | 2022-09-21 |
| Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial Dexmedetomidine - Sepsis | Phase 4 | Completed | Wakayama Medical University | 203 | 2013-01-01 | 2017-02-28 |
Sepsis (2) · Cross Infection (1) · Diabetes Mellitus, Type 2 (1) · Gout (1) · Heart Failure (1) · Hypertension (1) · Hyperuricemia (1) · Pneumonia, Ventilator-Associated (1) · Renal Insufficiency, Chronic (1)
Dexmedetomidine (1) · Febuxostat (1) · dotinurad (1) · finerenone (1) · sacubitril and valsartan sodium hydrate drug combination (1)
Japan (5)
Koichi Node, Pr.,Dr. (2) · Hitoshi Yamamura, doctor (1) · Jumpei Yoshimura, MD (1) · Kazuma Yamakawa, MD, PhD (1) · Koichi Node, MD, PhD (1) · Takeshi Morimoto, MD, PhD, MPH (1) · Takeshi Morimoto, doctor (1) · Yu Kawazoe (1)
PMID 27716402, PMID 28322414, PMID 29497535, PMID 30409160, PMID 31908779, PMID 32778146, PMID 35394515, PMID 37525257, PMID 39215531, PMID 40389107, PMID 42542200