6 completed. 6 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine Used With Treatment Resistant Depression in Older Adults venlafaxine XR, buprenorphine, Placebo - Major Depressive Disorder, Depression | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 18 | 2016-06-01 | 2019-06-04 |
| Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine venlafaxine, buprenorphine, placebo - Major Depressive Disorder, Depression | Phase 1 / Phase 2 | Completed | Centre for Addiction and Mental Health | 56 | 2014-12-01 | 2018-07-26 |
| Safety and Efficacy of Mucinex and IR Guaifenesin the Treatment of Symptoms of Acute Upper Respiratory Tract Infections Mucinex, Immediate-release Guaifenesin, Placebo - Acute Upper Respiratory Tract Infection | Phase 2 / Phase 3 | Completed | Reckitt Benckiser LLC | 2810 | 2011-09-01 | 2013-11-14 |
| Buprenorphine for Late-Life Treatment Resistant Depression Buprenorphine - Depression | Phase 2 | Completed | University of Pittsburgh | 15 | 2010-05-01 | 2018-03-09 |
| Evaluating the Effect of Mucinex 1200mg on Mucociliary and Cough Clearance During an Acute Respiratory Infection Mucinex, Placebo - Acute Respiratory Infection | Phase 2 | Completed | Reckitt Benckiser LLC | 38 | 2010-04-01 | 2018-09-19 |
| Study of Two Formulations of Buprenorphine HCl in Opioid-dependent Subjects on Buprenorphine Maintenance Therapy (Study P04451) (COMPLETED) Buprenorphine hydrochloride marketed sublingual tablet (Subutex), Buprenorphine hydrochloride fast dissolving tablet (FDT) - Opioid Dependency | Phase 2 | Completed | Indivior Inc. | 52 | 2005-09-01 | 2023-04-11 |
Depression (3) · Depressive Disorder, Major (3)
Buprenorphine (4) · Acetylcysteine (2) · Buprenorphine, Naloxone Drug Combination (2) · Venlafaxine Hydrochloride (2) · Guaifenesin (1)
United States (4) · Canada (1)
Daniel M Blumberger, MD (1) · Eric J Lenze, MD (1) · Jordan F Karp, M.D. (1) · William Bennett, PhD (1)
PMID 25191915, PMID 26462765, PMID 31846575
KL2RR024154 (1)