PharmaEngine: Clinical Trials

12 trials sponsored by PharmaEngine, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

6 completed, 3 recruiting, 2 terminated, 1 unknown. 8 Phase 1, 6 Phase 2, 1 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 18Completed 3, Recruiting 3, Terminated 2
Phase 26Completed 3, Terminated 2, Unknown 1
Phase 31Completed 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Study of PEP08 in Patients With MTAP-Del Advanced or Metastatic Solid Tumors
PEP08 - Advanced Solid Tumor, Solid Tumors
Phase 1RecruitingPharmaEngine402025-08-262026-02-13
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients with Advanced or Metastatic Solid Tumors
PEP07 - Advanced Solid Tumor, Metastatic Solid Tumor
Phase 1RecruitingPharmaEngine542024-03-272024-11-07
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer
PEP07 - Acute Myeloid Leukemia, Lymphoma, Mantle-Cell
Phase 1RecruitingPharmaEngine322023-07-172025-07-31
Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors
Nanoliposomal Irinotecan - Refractory Solid Tumors
Phase 1CompletedPharmaEngine442019-03-052023-11-18
A Study of PEP503 With Radiotherapy in Combination With Concurrent Chemotherapy for Patients With Head and Neck Cancer
PEP503, Cisplatin, Radiotherapy - Head and Neck Squamous Cell Carcinoma
Phase 1 / Phase 2TerminatedPharmaEngine122016-10-112022-01-11
A Study of PEP503(Radio-enhancer) With Radiotherapy and Chemotherapy for Patients With Rectal Cancer
PEP503, 5-fluorouracil, capecitabine - Rectal Cancer
Phase 1 / Phase 2TerminatedPharmaEngine322015-06-012022-01-11
NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall
NBTXR3, Radiation therapy - Adult Soft Tissue Sarcoma
Phase 2 / Phase 3CompletedNanobiotix1802015-03-032021-04-06
Phase I and Pharmacokinetic Study of Biweekly PEP02 in mCRC Refractory to 1st-line Oxaliplatin Base Therapy
PEP02 - Metastatic Colorectal Cancer
Phase 1CompletedPharmaEngine182009-06-012017-04-06
Study of PEP02 as a Second Line Therapy for Metastatic Pancreatic Cancer
PEP02 - Pancreatic Neoplasms
Phase 2CompletedPharmaEngine412009-01-012019-09-06
Study of PEP02, Irinotecan or Docetaxel in Gastric or Gastroesophageal Junction Adenocarcinoma
PEP02, irinotecan, docetaxel - Stomach Neoplasms, Esophageal Neoplasms
Phase 2CompletedPharmaEngine1352007-11-012012-03-02
A Study of PEP02 in Combination With 5-fluorouracil (5-FU) and Leucovorin (LV) in Advanced Solid Tumors
PEP02, 5-FU, LV - Solid Tumor
Phase 1CompletedPharmaEngine162006-01-012016-08-30
Two-Stage Study to Assess the Efficacy and Safety of 12 Weeks of Treatment With PEP03 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
PEP03 - COPD
Phase 2UnknownPharmaEngine2004-09-012005-09-22

Conditions studied

Neoplasm Metastasis (3)  ·  Adenocarcinoma (1)  ·  Colorectal Neoplasms (1)  ·  Esophageal Neoplasms (1)  ·  Leukemia, Myeloid, Acute (1)  ·  Lymphoma, Mantle-Cell (1)  ·  Pancreatic Neoplasms (1)  ·  Pulmonary Disease, Chronic Obstructive (1)  ·  Rectal Neoplasms (1)  ·  Sarcoma (1)  ·  Squamous Cell Carcinoma of Head and Neck (1)  ·  Stomach Neoplasms (1)

Interventions

Radiotherapy (3)  ·  Fluorouracil (2)  ·  irinotecan sucrosofate (2)  ·  Capecitabine (1)  ·  Cisplatin (1)  ·  Docetaxel (1)  ·  Irinotecan (1)  ·  Leucovorin (1)  ·  trifluridine tipiracil drug combination (1)

Countries

Taiwan (10)  ·  Australia (3)  ·  Spain (2)  ·  Belgium (1)  ·  Bosnia and Herzegovina (1)  ·  Croatia (1)  ·  France (1)  ·  Germany (1)  ·  Hong Kong (1)  ·  Hungary (1)  ·  Italy (1)  ·  Norway (1)  ·  Philippines (1)  ·  Poland (1)  ·  Romania (1)

Top investigators

Andrew H Ko, M.D. (1)  ·  Cheng-Hsu Wang, M.D. (1)  ·  Chia-Chi Lin, MD (1)  ·  David Cunningham (1)  ·  Hsin-An Hou, M.D. (1)  ·  Jwa-Yuan Wang, phD (1)  ·  Li-Tzong Chen, M.D. (1)  ·  Yu-Lin Lin, M.D. (1)

Results publications

PMID 19525947, PMID 23406728, PMID 23880820, PMID 27871319, PMID 31296491, PMID 37166053, PMID 40255171