45 completed, 16 recruiting, 3 active not recruiting, 2 terminated. 5 Phase 2, 4 Phase 3, 4 Phase 4, 3 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Terminated 1 |
| Phase 3 | 4 | Completed 3, Withdrawn 1 |
| Phase 4 | 4 | Completed 4 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer Elacestrant, Standard of care (Investigator Choice) - Breast Cancer | Recruiting | iOMEDICO AG | 500 | 2026-06-19 | 2026-06-25 | |
| A Non-interventional Study of Melphalan Flufenamide (Melflufen) (Pepaxti®) and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma (R/RMM) Multiple Myeloma | Recruiting | iOMEDICO AG | 50 | 2026-06-01 | 2026-06-26 | |
| Research Platform Myelofibrosis and Anemia Primary Myelofibrosis, Secondary Myelofibrosis | Recruiting | iOMEDICO AG | 200 | 2026-02-19 | 2026-06-05 | |
| Vorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse Glioma Vorasidenib - Glioma | Recruiting | iOMEDICO AG | 150 | 2025-12-08 | 2026-01-09 | |
| Fruquintinib in Patients With Metastatic Colorectal Cancer Metastatic Colorectal Cancer (mCRC) | Recruiting | iOMEDICO AG | 150 | 2025-02-17 | 2026-09-04 | |
| Ropeginterferon Alfa-2b in Patients With Polycythemia Vera (PV) Without Symptomatic Splenomegaly Polycythemia Vera | Recruiting | iOMEDICO AG | 200 | 2024-12-03 | 2026-01-09 | |
| Ripretinib (QINLOCK®) According to Current SmPC Ripretinib - GIST - Gastrointestinal Stromal Tumor | Completed | iOMEDICO AG | 10 | 2024-10-17 | 2025-12-05 | |
| Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study Cholangiocarcinoma | Recruiting | iOMEDICO AG | 100 | 2024-10-08 | 2026-10-22 | |
| Ivosidenib (TIBSOVO®) Combined With Azacitidine According to Current SmPC Ivosidenib - Acute Myeloid Leukemia (AML) | Completed | iOMEDICO AG | 8 | 2023-12-20 | 2026-02-10 | |
| Registry Platform Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms Routine care as per site standard. - Chronic Lymphocytic Leukemia (CLL), Diffuse Large B-cell Lymphoma (DLBCL) | Recruiting | iOMEDICO AG | 2950 | 2023-09-27 | 2026-07-13 | |
| Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma Selinexor - Multiple Myeloma | Active not recruiting | iOMEDICO AG | 75 | 2023-06-28 | 2026-01-14 | |
| Acalabrutinib in Patients With Chronic Lymphocytic Leukemia With Direct Oral Anticoagulation (CICERO) Calquence - CLL | Completed | iOMEDICO AG | 45 | 2022-10-12 | 2026-05-01 | |
| Non-interventional Study to Evaluate Patient and Healthcare Provider Satisfaction of Daratumumab Use in the Treatment of First-line Daratumumab, Lenalidomide, Dexamethasone (DRd) Multiple Myeloma Patients in Germany Depending on Application Route (sc or iv) Daratumumab - Multiple Myeloma, Newly Diagnosed | Completed | iOMEDICO AG | 96 | 2022-07-06 | 2024-10-01 | |
| Tucatinib in Patients With Locally Advanced or Metastatic HER2-positive Breast Cancer Who Received at Least Two Prior Anti-HER2 Treatment Regimens. TUKYSA® - HER2-positive Breast Cancer | Completed | iOMEDICO AG | 49 | 2022-05-21 | 2025-12-04 | |
| Zanubrutinib in Patients With Waldenström's Macroglobulinemia, Chronic Lymphocytic Leukemia, Marginal Zone Lymphoma and Follicular Lymphoma Zanubrutinib, Obinutuzumab - Waldenström's Macroglobulinemia, Chronic Lymphocytic Leukemia | Recruiting | iOMEDICO AG | 845 | 2022-04-26 | 2026-09-09 | |
| Registry Platform Ovarian and Endometrial Cancer Physician's choice according to patient's needs. - Ovarian Cancer, Endometrial Cancer | Recruiting | iOMEDICO AG | 1975 | 2021-11-25 | 2026-01-28 | |
| Registry Platform Colorectal Cancer Physician's choice according to patient's needs. - Colorectal Cancer Metastatic | Active not recruiting | iOMEDICO AG | 500 | 2021-05-01 | 2026-07-13 | |
| Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion NTRK Family Gene Mutation | Completed | iOMEDICO AG | 88 | 2020-12-02 | 2025-05-01 | |
| BRAF Inhibitor Encorafenib And Cetuximab Real Life Investigation of Next Generation CRC Treatment Encorafenib, Cetuximab - Metastatic Colorectal Carcinoma | Recruiting | Pierre Fabre Pharma GmbH | 500 | 2020-09-03 | 2022-09-29 | |
| Liver Cancer Registry Platform Physician's choice according to patient's needs. - Hepatocellular Carcinoma (HCC), Cholangiocarcinoma | Active not recruiting | iOMEDICO AG | 1000 | 2020-08-09 | 2026-08-25 |
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Breast Neoplasms (17) · Multiple Myeloma (8) · Neoplasm Metastasis (8) · Carcinoma, Renal Cell (6) · Colorectal Neoplasms (6) · Carcinoma, Non-Small-Cell Lung (5) · Neoplasms (4) · Leukemia, Lymphocytic, Chronic, B-Cell (3) · Lymphoma, B-Cell, Marginal Zone (3) · Lymphoma, Follicular (3) · Lymphoma, Non-Hodgkin (3) · Anemia (2) · Cholangiocarcinoma (2) · Head and Neck Neoplasms (2) · Leukemia, Myeloid, Acute (2)
Capecitabine (5) · Vinorelbine (4) · Bevacizumab (3) · Everolimus (3) · Cetuximab (2) · Fulvestrant (2) · Panitumumab (2) · Sorafenib (2) · exemestane (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Anastrozole (1) · Aromatase Inhibitors (1) · Carboplatin (1) · Data Collection (1)
Germany (64) · Austria (5) · Switzerland (3)
Norbert Marschner, MD (4) · Karin Potthoff, Dr. (3) · Anja Welt, Dr. (2) · Jens Kisro, Dr. (2) · Tobias Dechow, Prof. Dr. (2) · Achim Kautz (1) · Anja Welt, MD (1) · Anja Welt, PD Dr. (1) · Anke Reinacher-Schick, Prof. (1) · Benjamin Kasenda, PD Dr. Dr. (1) · Christian Gratzke, Prof. Dr. (1) · Christoph Salat, Prof. (1)
PMID 33218965, PMID 21858552, PMID 23855804, PMID 24321255, PMID 24733536, PMID 24742019, PMID 25486127, PMID 25945067, PMID 25952317, PMID 26520429, PMID 26908232, PMID 26966573, PMID 27101285, PMID 27720164, PMID 28743247, PMID 28916198, PMID 29874105, PMID 30061035, PMID 30069704, PMID 30131294, PMID 30885347, PMID 31115844, PMID 31314918, PMID 32383192, PMID 32738823, PMID 33070307, PMID 33358484, PMID 33956213, PMID 34714555, PMID 36180086, PMID 36757197, PMID 36807725, PMID 37146227, PMID 37260368, PMID 37312086, PMID 38329180, PMID 39707595, PMID 40028796, PMID 41851017, PMID 41927857, PMID 42820722, PMID 42853423
2008 (1), 2009 (1), 2014 (1), 2017 (1)