7 completed, 2 unknown, 1 recruiting. 5 Not applicable, 3 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Recruiting 1, Unknown 1 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow xylometazoline: new trials by email Literature Review of xylometazoline trials Research Report on xylometazoline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxytocin's Effects on Emotional Processing and Its Acting Routes placebo (compared to vasoconstrictor), vasoconstrictor (Otrivin), placebo (compared to oxytocin) - Healthy Adult Male | Not applicable | Recruiting | University of Electronic Science and Technology of China | 120 | 2026-01-24 | 2026-02-23 |
| Safety and Efficacy of DSM 32444 Postbiotic in the Treatment of Acute Rhinosinusitis Neomycin/ Dexameythasone/Xylometazoline, Bacillus subtilis DSM32444 - Rhinosinusitis, Rhinitis | Not applicable | Completed | Huro Biotech Joint Stock Company | 60 | 2022-12-29 | 2024-03-05 |
| LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media 0.9% NaCl physiological saline Nasal-spraying, LiveSpo Navax®, Augmentin 500Mg Tablet - Upper Respiratory Tract Infections | Not applicable | Completed | Anabio R&D | 175 | 2021-10-28 | 2024-08-22 |
| Nasal Breathing and Physical Capacity Otrivin - Nasal Obstruction, Copd | Phase 4 | Unknown | Sorlandet Hospital HF | 67 | 2021-01-13 | 2023-06-27 |
| Xylometazoline During Nasal Flexible Bronchoscopy Xylometazoline, Saline - Bronchoscopy | Not applicable | Completed | All India Institute of Medical Sciences | 148 | 2018-06-01 | 2019-03-11 |
| The Role of the Nose in Snoring and Sleep Apnea Xylometazoline, placebo (saline) - Nasal Obstruction, Apnea, Obstructive Sleep | Not applicable | Unknown | Lovisenberg Diakonale Hospital | 30 | 2017-03-01 | 2017-03-07 |
| Nasal Prep for Nasendoscopy in Children 0.05% xylometazoline hydrochloride with 1% lidocaine hydrochloride, 0.05% xylometazoline hydrochloride, Isotonic normal saline - Flexible Nasendoscopy | Phase 4 | Completed | Children's & Women's Health Centre of British Columbia | 69 | 2011-06-01 | 2012-12-06 |
| Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold Xylometazoline - Common Cold | Phase 3 | Completed | Novartis | 60 | 2007-03-01 | 2007-05-03 |
| Evaluation of Safety of ZyComb® In Patients With Common Cold - ZIP 3000 (XY-005-IM) xylometazoline hydrochloride and ipratropium bromide (ZyComb) - Common Cold | Completed | Nycomed | 1000 | 2006-12-01 | 2012-05-07 | |
| Nasal Decongestion and Obstructive Sleep Apnea xylometazoline - Obstructive Sleep Apnea Syndrome, Rhinitis | Phase 4 | Completed | University of Zurich | 12 | 2004-01-01 | 2009-12-23 |
Common Cold (2) · Nasal Obstruction (2) · Rhinitis (2) · Sleep Apnea, Obstructive (2) · Otitis Media (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Tract Infections (1) · Rhinitis, Allergic, Perennial (1) · Rhinosinusitis (1) · Sleep Apnea Syndromes (1)
All India Institute of Medical Sciences (1) · Anabio R&D (1) · Children's & Women's Health Centre of British Columbia (1) · Huro Biotech Joint Stock Company (1) · Lovisenberg Diakonale Hospital (1) · Novartis (1) · Nycomed (1) · Sorlandet Hospital HF (1) · University of Electronic Science and Technology of China (1) · University of Zurich (1)
Norway (2) · Vietnam (2) · Canada (1) · China (1) · India (1) · Switzerland (1) · United Kingdom (1)
Binh Nguyen Thanh, Assoc. Prof. (1) · Karan Madan, MD, DM (1) · Konrad E Bloch, MD (1) · Shuxia Yao, Dr (1) · Thanh Khieu Huu, MD.,PhD (1)
PMID 18710420, PMID 19823201, PMID 24158493, PMID 32502854, PMID 33518471, PMID 36791622, PMID 39870748