25 completed, 4 terminated, 3 withdrawn, 1 not yet recruiting. 11 Phase 4, 9 Phase 3, 8 Not applicable, 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 5, Withdrawn 3, Terminated 2, Not yet recruiting 1 |
| Phase 3 | 9 | Completed 9 |
| Not applicable | 8 | Completed 5, Terminated 2, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
Follow Ventolin: new trials by email Literature Review of Ventolin trials Research Report on Ventolin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD) Revefenacin, formoterol fumarate, Placebo (Sterile Normal Saline) - COPD Exacerbation | Phase 4 | Not yet recruiting | University of Tennessee Graduate School of Medicine | 280 | 2026-11-12 | 2026-10-19 |
| Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study) Salbutamol, Ipratropium Bromide, Salbutamol plus Ipratropium Bromide - Asthma, Airway Obstruction | Not applicable | Unknown | Hat Yai Medical Education Center | 60 | 2024-02-17 | 2024-02-20 |
| Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes Control, Albuterol - Asthma in Children, Dyspnea; Asthmatic | Phase 4 | Withdrawn | Ohio State University | 2023-07-01 | 2023-11-07 | |
| Different Doses of Nebulized Magnesium Sulphate in Status Asthmaticus Magnesium Sulfate 500 mg/ml+ ventolin, Ventolin - Status Asthmaticus | Phase 1 | Completed | Ziauddin University | 126 | 2022-01-01 | 2023-04-05 |
| Bronchodilators for Wheeze in Young Children Presenting to Primary Care: a Randomised, Placebo-controlled, Multicentre, Parallel Group Trial Salbutamol, Placebo - Wheezing | Phase 4 | Withdrawn | UMC Utrecht | 2021-09-01 | 2021-07-23 | |
| Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence Tomography Tiotropium Inhalation Powder [Spiriva] 0.018mg, Salbutamol sulphate aerosol (Ventolin) 0.1mg - Airway Remodeling, Chronic Obstructive Pulmonary Disease | Not applicable | Completed | Guangzhou Institute of Respiratory Disease | 84 | 2019-08-01 | 2026-10-21 |
| Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity Albuterol Sulfate, Interval Warm-up exercise - Asthma in Children, Obesity, Childhood | Phase 4 | Terminated | University of Nevada, Las Vegas | 34 | 2018-09-18 | 2021-07-22 |
| Safety and Efficacy of Albuterol Administered by the Halix™ Dry Powder Inhaler in Subjects With Asthma Halix albuterol 90 mcg, albuterol HFA MDI 90 mcg - Asthma | Phase 2 | Completed | Concentrx Pharmaceuticals, Inc. | 13 | 2018-06-30 | 2019-01-30 |
| Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma. CMAB007, Symbicort, Seretide - Asthma, Allergic | Phase 3 | Completed | Shanghai Biomabs Pharmaceutical Co., Ltd. | 393 | 2018-05-09 | 2021-10-11 |
| Evaluation on the Efficacy of Bronchodilator Nebulization Via High Flow Nasal Cannula High flow nasal cannula, Albuterol Sulfate - High Flow Nasal Cannula | Not applicable | Completed | Rush University Medical Center | 42 | 2017-09-04 | 2018-04-04 |
| Repeat Emergency Department Visits Among Patients With Asthma and COPD beclamethasone dipropionate, albuterol, Prednisone - Asthma, COPD | Not applicable | Terminated | State University of New York at Buffalo | 6 | 2016-01-01 | 2019-06-04 |
| Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning Standard care, Standard care+ 2.5 mg Salbutamol, Standard care+ 5 mg Salbutamol - Organophosphate Poisoning | Phase 3 | Completed | Sylhet M.A.G.Osmani Medical College | 75 | 2015-04-01 | 2015-12-29 |
| Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPD Placebo, ipratropium bromide, salbutamol - Chronic Obstructive Pulmonary Disease (COPD) | Not applicable | Completed | Zhujiang Hospital | 22 | 2014-12-01 | 2015-07-28 |
| Supervised Asthma Medication in Schools (SAMS) Supervised asthma therapy in schools - Childhood Asthma | Phase 4 | Completed | University of Arizona | 442 | 2014-08-01 | 2022-03-23 |
| The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout - Asthma, Wheeze | Completed | The Hospital for Sick Children | 121 | 2014-06-01 | 2021-02-08 | |
| Preterm Infant Inhaled Albuterol Dosing Varied albuterol dose response - Bronchopulmonary Dysplasia, Very Low Birth Weight | Phase 4 | Completed | Oregon Health and Science University | 14 | 2013-10-24 | 2019-05-23 |
| Salbutamol, Pharmacogenetics and Breathing Mechanics Salbutamol, Placebo - Bronchoconstriction, Inhaled Salbutamol | Phase 4 | Completed | University of British Columbia | 94 | 2013-05-01 | 2016-11-02 |
| Efficacy Study of SYN006 HFA MDI in Asthma Patients Budesonide/Procaterol, 180/10mcg X1, Budesonide/procaterol 180/10 mcg X 2, Albuterol HFA MDI 100mcg X2 - Asthma | Phase 2 | Completed | Intech Biopharm Ltd. | 39 | 2013-02-01 | 2015-06-03 |
| IPF Drug Deposition Study Salbutamol - Idiopathic Pulmonary Fibrosis | Phase 1 | Completed | Royal Brompton & Harefield NHS Foundation Trust | 10 | 2012-04-01 | 2014-11-05 |
| Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes Albuterol - Experimental, Albuterol - Control - Asthma, Children | Not applicable | Completed | University of Sao Paulo | 119 | 2011-09-01 | 2016-03-14 |
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Asthma (16) · Pulmonary Disease, Chronic Obstructive (7) · Airway Remodeling (2) · Conjunctivitis (2) · Hypersensitivity (2) · Pediatric Obesity (2) · Respiratory Sounds (2) · Rhinitis (2) · Airway Obstruction (1) · Asthma, Exercise-Induced (1) · Autonomic Nervous System Diseases (1) · Bronchopulmonary Dysplasia (1) · Cystic Fibrosis (1) · Dyspnea (1) · Emergencies (1)
ALK-Abelló A/S (2) · AstraZeneca (2) · University of Dundee (2) · Chiesi Farmaceutici S.p.A. (1) · Concentrx Pharmaceuticals, Inc. (1) · Guangzhou Institute of Respiratory Disease (1) · Hat Yai Medical Education Center (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Imperial College London (1) · Intech Biopharm Ltd. (1) · Laval University (1) · Mayo Clinic (1) · Northwell Health (1) · Ohio State University (1) · Oregon Health and Science University (1)
United States (11) · United Kingdom (5) · Canada (4) · China (4) · Italy (2) · Bangladesh (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · Croatia (1) · Czechia (1) · France (1) · Germany (1) · Pakistan (1) · Poland (1)
Brian J Lipworth, MBchB (2) · Catherine Bonuccelli (2) · Karine L Clearie, MBBS, MRCP (2) · Alberto Papi, Professor (1) · Amanda Kim, MD (1) · Andrew G Engel, MD (1) · Ann van den Bruel, Professor (1) · Chen Xin, Doctor (1) · Cynthia McEvoy, MD, MCR (1) · Dharini M Bhammar, MBBS, PhD (1) · Dharini M Bhammar, Ph.D. (1) · Fazle R Chowdhury, FCPS (1) · Heather A Lindstrom, PhD (1) · Karina Serban, MD (1) · Louis-Philippe Boulet, MD (1)
PMID 25685162, PMID 21211642, PMID 21211643, PMID 23829494, PMID 24321801, PMID 27171324, PMID 29409488, PMID 30118728, PMID 31695864, PMID 35352766, PMID 38827880, PMID 41345745
2008 (1), R18HL110858 (1)