6 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 9 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 9 | Completed 6, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Vehicle Control: new trials by email Literature Review of Vehicle Control trials Research Report on Vehicle Control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase III Study of Topical Fibrinogen-Depleted Human Platelet Lysate Compared to Placebo for Moderate to Severe Dry Eye CAM-101, Vehicle Control - Dry Eye Disease, Dry Eye | Phase 3 | Not yet recruiting | Cambium Bio Limited | 475 | 2026-10-01 | 2026-06-12 |
| Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2 RGN-259, Placebo - Neurotrophic Keratopathy | Phase 3 | Recruiting | ReGenTree, LLC | 70 | 2023-04-11 | 2025-12-23 |
| Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study Lotilaner, Vehicle Control - Blepharitis | Phase 3 | Completed | LianBio LLC | 163 | 2022-10-23 | 2024-05-21 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 RGN-259, Placebo - Dry Eye Syndromes, Dry Eye | Phase 3 | Completed | ReGenTree, LLC | 700 | 2019-05-24 | 2026-08-28 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 RGN-259, Placebo - Dry Eye Syndrome | Phase 3 | Completed | ReGenTree, LLC | 601 | 2016-11-01 | 2026-10-21 |
| Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1 RGN-259, Placebo - Neurotrophic Keratopathy | Phase 3 | Terminated | ReGenTree, LLC | 18 | 2015-09-17 | 2023-08-30 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1 RGN-259, Placebo - Dry Eye Syndrome | Phase 2 / Phase 3 | Completed | ReGenTree, LLC | 317 | 2015-09-01 | 2019-10-17 |
| Safety and Efficacy of Generic Diclofenac Epolamine Acute Pain Due to Minor Ankle Sprain Diclofenac epolamine, Placebo - Ankle Sprain | Phase 3 | Completed | Actavis Inc. | 658 | 2014-05-01 | 2020-06-24 |
| A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation Ivermectin Cream, vehicle control - Head Lice | Phase 3 | Completed | Topaz Pharmaceuticals Inc | 410 | 2010-03-01 | 2012-04-06 |
Dry Eye Syndromes (4) · Ankle Injuries (1) · Blepharitis (1)
ReGenTree, LLC (5) · Actavis Inc. (1) · Cambium Bio Limited (1) · LianBio LLC (1) · Topaz Pharmaceuticals Inc (1)
United States (7) · China (1) · Italy (1) · Poland (1) · Spain (1)
Gail Torkildsen, MD (2) · Henry Lau, PhD (1) · Neera Jagirdar, MD MPH (1) · Zuguo Liu, M.D (1)