3 completed, 2 terminated. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Terminated 2 |
Follow varespladib: new trials by email Literature Review of varespladib trials Research Report on varespladib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Broad-spectrum Rapid Antidote: Varespladib IV to Oral Trial for Snakebite (BRAVIO) Varespladib intravenous form, varespladib-methyl- oral form, Placebo intravenous form - Snakebite, Envenoming, Snake | Phase 2 | Completed | Ophirex, Inc. | 140 | 2023-05-30 | 2025-06-27 |
| Study of Varespladib in Patients Hospitalized With Severe COVID-19 Varespladib, Placebo - Coronavirus Disease 2019, Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2 | Phase 2 | Terminated | Ophirex, Inc. | 18 | 2021-06-30 | 2025-05-15 |
| A Study of Varespladib Infusion in Subjects With Sickle Cell Disease. Varespladib, Placebo (Normal Saline) - Sickle Cell Disease, Vaso-occlusive Crisis | Phase 2 | Terminated | Anthera Pharmaceuticals | 2 | 2012-02-01 | 2014-03-04 |
| FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes Varespladib Methyl (A-002) - Acute Coronary Syndrome | Phase 2 | Completed | Anthera Pharmaceuticals | 625 | 2008-07-01 | 2014-03-04 |
| sPLA2 Inhibition to Decrease Enzyme Release After PCI Trial Varespladib (A-002), placebo - Coronary Artery Disease | Phase 2 | Completed | University Health Network, Toronto | 164 | 2007-10-01 | 2009-10-09 |
Acute Coronary Syndrome (1) · Anemia, Sickle Cell (1) · Angina, Unstable (1) · COVID-19 (1) · Coronary Artery Disease (1) · Non-ST Elevated Myocardial Infarction (1) · Respiratory Distress Syndrome (1) · ST Elevation Myocardial Infarction (1) · Snake Bites (1) · Vaso-Occlusive Crises (1)
Anthera Pharmaceuticals (2) · Ophirex, Inc. (2) · University Health Network, Toronto (1)
United States (3) · Canada (1) · Georgia (1) · Russia (1) · Ukraine (1)
Timothy Platts-Mills, MD, MSc (1) · Vladimir Dzavik, MD (1)