6 completed, 5 unknown, 2 withdrawn, 1 not yet recruiting. 6 Not applicable, 5 Phase 3, 3 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Unknown 1, Withdrawn 1 |
| Phase 3 | 5 | Completed 2, Recruiting 1, Terminated 1, Unknown 1 |
| Phase 4 | 3 | Unknown 2, Withdrawn 1 |
| Phase 1 | 1 | Unknown 1 |
Follow urapidil: new trials by email Literature Review of urapidil trials Research Report on urapidil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety Study of Urapidil Alone or With Esmolol in Treating Acute Hypertensive Intracerebral Hemorrhage Urapidil, Urapidil and Esmolol - Hypertensive Intracerebral Hemorrhage | Not yet recruiting | Qianfoshan Hospital | 600 | 2024-11-01 | 2024-10-10 | |
| Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2) BP lowering drugs (nicardipine, labetalol, urapidil), BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil) - Acute Ischemic Stroke | Phase 3 | Recruiting | Yonsei University | 176 | 2024-10-01 | 2026-02-13 |
| Hemodynamic Optimization of Cerebral Perfusion After Endovascular Therapy in Patients With Acute Ischemic Stroke Adjusted medication - Acute Ischemic Stroke | Phase 4 | Unknown | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 814 | 2021-06-01 | 2023-03-16 |
| Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial urapidil - Stroke, Acute, Cerebrovascular Disorders | Phase 3 | Completed | The George Institute for Global Health, China | 2425 | 2020-03-20 | 2025-03-26 |
| Effects of Different Kinds of Hypotensive Drugs on Dynamic Hemodynamic Changing in Patients Under Surgeries Nicardipine, Urapidil - General Surgery | Not applicable | Completed | Chinese PLA General Hospital | 59 | 2018-04-15 | 2020-08-26 |
| TCD Monitoring Technology Guides the Precise Control of Blood Pressure After EVT Urapidil Hydrochloride Injection - Acute Ischemic Stroke | Phase 4 | Unknown | Xuanwu Hospital, Beijing | 90 | 2018-04-08 | 2018-05-18 |
| Clevidipine (Cleviprex®) Compared With Urapidil (Ebrantil®) Clevidipine, Urapidil - Nontraumatic Intracerebral Hemorrhage, Multiple Localized | Phase 4 | Withdrawn | University of Zurich | 2017-06-15 | 2021-11-08 | |
| Intensive Blood PRessure Control in Patients With Acute Type B AortIc Dissection Urapidil Hydrochloride Injection - Blood High Pressure, Aortic Dissection Type B | Phase 1 | Unknown | Sir Run Run Shaw Hospital | 360 | 2016-12-01 | 2016-12-23 |
| Effect of High vs. Low MAP Levels on Clinical Outcomes in Elderly Patients During Noncardiothoracic Surgery Urapidil, Phenylephrine, Low-level MAP - Aging, Surgery | Not applicable | Unknown | Hu Anmin | 322 | 2016-07-01 | 2016-08-16 |
| The Treatment of Hypertension Associated With Severe Preeclampsia (PE). A Trial of Urapidil Versus Nicardipine Urapidil, Nicardipine - Hypertension, Preeclampsia | Phase 3 | Terminated | University Hospital, Strasbourg, France | 14 | 2015-09-01 | 2020-08-25 |
| Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery Pupillometry guided analgesia (PP), Tailored remifentanil controlled infusion, Tailored antihypertensive drug administration - Scheduled Laparoscopic Surgery | Not applicable | Completed | Central Hospital, Nancy, France | 100 | 2014-03-01 | 2019-11-01 |
| Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) Low-dose rtPA, Standard-dose rtPA, Intensive blood pressure (BP) lowering - Ischemic Stroke, High Blood Pressure | Phase 3 | Completed | The George Institute | 4587 | 2012-03-01 | 2021-10-13 |
| The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial Blood pressure management policies - Intracerebral Hemorrhage, Stroke | Not applicable | Completed | The George Institute | 2839 | 2008-09-01 | 2013-12-13 |
| Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine URAPIDIL (EUPRESSYL*), NICARDIPINE - Hypertension During Pre-Eclampsia | Phase 3 | Unknown | University Hospital, Strasbourg, France | 72 | 2007-06-01 | 2009-02-25 |
| Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Labetalol Hydrochloride, Metoprolol tartrate, Hydralazine Hydrochloride - CVA (Cerebrovascular Accident), Cerebral Hemorrhage | Not applicable | Completed | The George Institute | 404 | 2005-11-01 | 2008-06-26 |
| Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation cafedrine/theodrenaline, urapidil - Cerebral Ischemia | Not applicable | Withdrawn | University Hospital Schleswig-Holstein | 2014-05-22 |
Hypertension (5) · Ischemic Stroke (4) · Stroke (3) · Cerebral Hemorrhage (2) · Agnosia (1) · Blood Loss, Surgical (1) · Brain Ischemia (1) · Cerebrovascular Disorders (1) · Emergence Delirium (1) · Hemorrhage (1) · Intracranial Hemorrhage, Hypertensive (1) · Intracranial Hemorrhages (1) · Pre-Eclampsia (1)
The George Institute (3) · University Hospital, Strasbourg, France (2) · Central Hospital, Nancy, France (1) · Chinese PLA General Hospital (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Hu Anmin (1) · Qianfoshan Hospital (1) · Sir Run Run Shaw Hospital (1) · The George Institute for Global Health, China (1) · University Hospital Schleswig-Holstein (1) · University of Zurich (1) · Xuanwu Hospital, Beijing (1) · Yonsei University (1)
China (7) · France (4) · Australia (3) · Germany (2) · Spain (2) · Switzerland (2) · Argentina (1) · Austria (1) · Belgium (1) · Brazil (1) · Chile (1) · Finland (1) · Hong Kong (1) · India (1) · Italy (1)
Craig Anderson, PhD (2) · Bruce Neal, PhD (1) · Craig Anderson (1) · Craig S Anderson, MD (1) · Emanuela Keller, MD Prof (1) · Gang Li (1) · Hu Anmin (1) · Jianjun Wang, Ph.D. (1) · Jie Yang (1) · Lili Song (1)
PMID 32640944, PMID 40541207, PMID 41855454, PMID 42848972, PMID 25503550, PMID 25589782, PMID 25657175, PMID 25712944, PMID 25823544, PMID 26746184, PMID 27165954, PMID 27178897, PMID 27919055, PMID 30890109, PMID 31085948, PMID 33598552, PMID 38018833, PMID 10839257, PMID 12145033, PMID 18396107, PMID 20823381, PMID 22129475, PMID 22678090, PMID 22744655, PMID 23713578, PMID 23835589, PMID 24149007, PMID 24530176, PMID 25497513, PMID 25677598, PMID 25801872, PMID 26044442, PMID 26083768, PMID 26148170, PMID 26202097, PMID 26265125, PMID 26810526, PMID 26814235, PMID 26846860, PMID 26859491, PMID 27009893, PMID 27073236, PMID 27143274, PMID 27161018, PMID 27831492, PMID 28235817, PMID 28616291, PMID 28619989, PMID 28739832, PMID 28973174
2017 (1)