4 completed, 1 recruiting, 1 terminated. 6 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Tirapazamine: new trials by email Literature Review of Tirapazamine trials Research Report on Tirapazamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer. tirapazamine, Transarterial Embolization (TAE), TACE - HCC | Phase 2 / Phase 3 | Recruiting | Zhejiang Raygene Pharmaceuticals Co., Ltd | 300 | 2025-03-27 | 2025-04-06 |
| Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer cisplatin, tirapazamine - Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma | Phase 3 | Terminated | National Cancer Institute (NCI) | 402 | 2006-02-01 | 2019-07-23 |
| TRACE: Tirapazamine-Radiation And Cisplatin Evaluation Tirapazamine, Cisplatin - Head and Neck Squamous Cell Carcinoma | Phase 3 | Completed | Sanofi | 317 | 2005-04-01 | 2016-05-26 |
| Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer tirapazamine (SR259075), cisplatin, Radiation Therapy - Head and Neck Neoplasms | Phase 3 | Completed | Sanofi | 861 | 2002-10-01 | 2010-02-15 |
| Combination Chemotherapy With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer carboplatin, paclitaxel, tirapazamine - Lung Cancer | Phase 3 | Completed | SWOG Cancer Research Network | 2000-11-01 | 2013-06-24 | |
| Cisplatin Plus Vinorelbine With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer cisplatin, tirapazamine, vinorelbine tartrate - Lung Cancer | Phase 3 | Completed | Sanofi | 2000-07-01 | 2013-08-02 |
Carcinoma, Non-Small-Cell Lung (2) · Head and Neck Neoplasms (2) · Lung Neoplasms (2) · Adenocarcinoma of Lung (1) · Carcinoma, Squamous Cell (1) · Laryngeal Diseases (1) · Squamous Cell Carcinoma of Head and Neck (1) · Uterine Cervical Neoplasms (1)
Sanofi (3) · National Cancer Institute (NCI) (1) · SWOG Cancer Research Network (1) · Zhejiang Raygene Pharmaceuticals Co., Ltd (1)
United States (5) · Canada (2) · Argentina (1) · Australia (1) · Chile (1) · China (1) · France (1) · Germany (1) · Hong Kong (1) · Hungary (1) · Italy (1) · New Zealand (1) · Poland (1) · Singapore (1) · South Africa (1)
Elwyn Y. Loh, MD (1) · Gaojun Teng, M.D (1) · Jiansong Ji, M.D (1) · Paul DiSilvestro (1) · Stephen K. Williamson, MD (1)
PMID 15251940, PMID 16361616, PMID 18779603, PMID 24395863, PMID 27209505
U10CA027469 (1)