6 completed, 2 recruiting, 1 active not recruiting, 1 terminated. 8 Phase 2, 1 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 5, Recruiting 2, Active not recruiting 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Td: new trials by email Literature Review of Td trials Research Report on Td
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial Biopsy, Biospecimen Collection, Computed Tomography - Advanced Fallopian Tube Carcinoma, Advanced Fallopian Tube High Grade Serous Adenocarcinoma | Phase 2 | Recruiting | Mayo Clinic | 78 | 2024-11-12 | 2026-10-02 |
| PFAS Exposure and Immune Response to Vaccination in Adults TENIVAC - Innate Inflammatory Response, Vaccination | Phase 4 | Completed | Rutgers, The State University of New Jersey | 20 | 2024-11-04 | 2025-12-30 |
| PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma PEP-CMV, Temozolomide, Tetanus Diphtheria Vaccine - High Grade Glioma, Diffuse Intrinsic Pontine Glioma | Phase 2 | Recruiting | Nationwide Children's Hospital | 120 | 2024-07-18 | 2026-08-24 |
| DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab Human CMV pp65-LAMP mRNA-pulsed autologous DCs, Temozolomide, Varlilumab - Glioblastoma | Phase 2 | Active not recruiting | Annick Desjardins, MD | 43 | 2020-08-26 | 2026-05-22 |
| Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens 5-day TMZ, 21-day TMZ, PEP-CMV: Component A - Glioblastoma, Glioblastoma Multiforme | Phase 1 | Terminated | Eric Thompson, M.D. | 27 | 2016-12-07 | 2022-06-09 |
| Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme pp65-shLAMP DC with GM-CSF, unpulsed PBMC and saline, Td - Glioblastoma Multiforme, Glioblastoma | Phase 2 | Completed | University of Florida | 175 | 2016-08-09 | 2025-01-14 |
| Maternal Tdap Immunization in Guatemala Tdap, Td - Pertussis, Whooping Cough | Phase 2 | Completed | Emory University | 286 | 2016-07-01 | 2019-10-16 |
| DC Migration Study for Newly-Diagnosed GBM Unpulsed DCs, Td, Human CMV pp65-LAMP mRNA-pulsed autologous DCs - Glioblastoma, Astrocytoma, Grade IV | Phase 2 | Completed | Mustafa Khasraw, MBChB, MD, FRCP, FRACP | 64 | 2015-10-12 | 2023-06-08 |
| Vaccination Response in Tecfidera-Treated Versus Interferon-Treated Participants With Relapsing Forms of Multiple Sclerosis. dimethyl fumarate, tetanus diphtheria toxoids vaccine, 23-valent pneumococcal polysaccharide vaccine - Relapsing Forms of Multiple Sclerosis | Phase 2 | Completed | Biogen | 71 | 2015-02-28 | 2017-06-02 |
| Pertussis Maternal Immunization Study Tdap, Td - Pregnant Women | Phase 2 / Phase 3 | Completed | Scott Halperin | 320 | 2007-11-01 | 2020-08-27 |
Glioblastoma (4) · Glioma (2) · Whooping Cough (2) · Diffuse Intrinsic Pontine Glioma (1) · Diphtheria (1) · Inflammation (1) · Medulloblastoma (1) · Tetanus (1)
Annick Desjardins, MD (1) · Biogen (1) · Emory University (1) · Eric Thompson, M.D. (1) · Mayo Clinic (1) · Mustafa Khasraw, MBChB, MD, FRCP, FRACP (1) · Nationwide Children's Hospital (1) · Rutgers, The State University of New Jersey (1) · Scott Halperin (1) · University of Florida (1)
United States (8) · Canada (1) · Guatemala (1)
Annick Desjardins, MD, FRCPC (1) · Daniel Landi, MD (1) · David Ashley, MBBS, FRACP, PhD (1) · Dina Randazzo, DO (1) · Duane Mitchell, MD, PhD (1) · Eric M Thompson, MD (1) · Maryam Fouladi, MD (1) · Maryam Rahman, MD (1) · Matthew S. Block, MD, PhD (1) · Robert Laumbach, MD (1) · Saad B. Omer, MBBS,MPH,PhD (1) · Scott A Halperin, MD (1)
PMID 29159204, PMID 30010773, PMID 38461048
R01CA175517 (1), R42CA153845 (1)