12 completed, 2 withdrawn. 7 Not applicable, 4 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Withdrawn 2 |
| Phase 4 | 4 | Completed 4 |
| Phase 1 | 1 | Completed 1 |
Follow Systane Ultra: new trials by email Literature Review of Systane Ultra trials Research Report on Systane Ultra
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Improved Efficacy of Selective Laser Trabeculoplasty With the Addition of Rocklatan Post-treatment vs Artificial Tears Post-treatment Rocklatan, Systane Ultra - Glaucoma | Completed | Colorado Ophthalmology Associates PC | 70 | 2025-02-14 | 2026-03-18 | |
| Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops Systane Complete, Systane Ultra - Dry Eye Syndromes, Keratoconjunctivitis Sicca | Not applicable | Completed | Ohio State University | 24 | 2018-12-05 | 2019-05-23 |
| Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects PRO-087, Systane Ultra, Xyel Ofteno - Dry Eye Syndromes, Lubricant Allergy | Phase 1 | Completed | Laboratorios Sophia S.A de C.V. | 30 | 2017-07-17 | 2019-07-19 |
| Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV) PRO-087, Systane Ultra, Systane Ultra Preservative Free - Dry Eye Syndrome | Phase 4 | Completed | Laboratorios Sophia S.A de C.V. | 326 | 2016-10-13 | 2019-10-31 |
| Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra) Rohto (r) Hydra, Systane (r) Ultra - Dry Eye | Phase 4 | Completed | ORA, Inc. | 48 | 2015-12-01 | 2023-06-27 |
| Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery Systane Ultra, tobradex quid (Standard) - Cataract | Not applicable | Completed | Democritus University of Thrace | 80 | 2015-01-01 | 2015-09-23 |
| Systane Ultra Versus Maxidex Versus Saline Systane Ultra, Saline solution, Maxidex - Dry Eye Disease | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 36 | 2012-05-01 | 2013-01-25 |
| Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time Systane Ultra, Optive - Dry Eye | Not applicable | Withdrawn | Alcon Research | 2011-07-01 | 2012-02-08 | |
| An Evaluation of a Marketed Lubricated Eye Drop in Soft Contact Lens Wearers Who Experience Ocular Dryness FID 112903 - Contact Lens Wear | Not applicable | Completed | Alcon Research | 92 | 2010-04-01 | 2016-11-21 |
| Evaluation of the Repeated Usage of Systane Ultra Eyedrop Systane Ultra, Optive lubricant Eye Drops - Dry Eye | Phase 4 | Completed | Alcon Research | 57 | 2009-11-01 | 2012-02-02 |
| Tears Substitutions and Their Effects on Higher Order Aberrometery Preservative Free Saline, Optive, Refresh Moderate/Severe - Dry Eye Syndrome | Not applicable | Withdrawn | Gina Rogers | 2009-01-01 | 2017-04-04 | |
| A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes Systane Ultra, Bausch and Lomb Sensitive Eyes - Dry Eye | Phase 4 | Completed | Durrie Vision | 30 | 2008-10-01 | 2012-09-20 |
| A 2-week Clinical Comparison of SYSTANE® Ultra to Sensitive Eyes Rewetting Drops in Contact Lens Wearing Patients. Systane Ultra, Sensitive Eyes Rewetting Drops - Dry Eye | Completed | Alcon Research | 47 | 2008-10-01 | 2012-02-02 | |
| Evaluation of SYSTANE Ultra Lubricant Eye Drops SYSTANE Ultra, Optive - Dry Eye | Not applicable | Completed | Alcon Research | 109 | 2008-06-01 | 2012-02-02 |
Dry Eye Syndromes (11) · Cataract (1) · Corneal Diseases (1) · Eye Diseases (1) · Glaucoma (1) · Keratitis (1) · Keratoconjunctivitis (1) · Keratoconjunctivitis Sicca (1) · Lacrimal Apparatus Diseases (1)
Alcon Research (5) · Laboratorios Sophia S.A de C.V. (2) · Colorado Ophthalmology Associates PC (1) · Democritus University of Thrace (1) · Durrie Vision (1) · Gina Rogers (1) · Icahn School of Medicine at Mount Sinai (1) · ORA, Inc. (1) · Ohio State University (1)
United States (5) · Mexico (2) · Greece (1)
Christine Sindt, OD (1) · Daniel S. Durrie, MD (1) · Georgios Labiris, MD, PhD (1) · Gina M Rogers, MD (1) · Keith Lane (1) · Kingsley Okafor, MD (1) · Leopoldo Baiza, MD (1) · Penny Asbell, MD, MBA, FACS (1)