7 unknown, 4 completed, 2 not yet recruiting, 1 recruiting. 10 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Unknown 5, Completed 3, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biomarkers and Pharmacogenomics for Precision Depression Therapy Pharmacogenomic Testing, Antidepressant Agents - Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 220 | 2026-07-01 | 2026-07-31 |
| A Multicentre Clinical Study SSRIs, fNIRS - the Objective Diagnosis of Depression | Not yet recruiting | Zhongda Hospital | 2250 | 2025-07-30 | 2025-07-14 | |
| Efficacy of Dextromethorphan-Bupropion Versus SSRIs in the Treatment of Major Depressive Disorder Dextromethorphan-Bupropion, SSRIs - Major Depressive Disorder (MDD) | Not applicable | Completed | Asad Ullah Jan | 80 | 2025-05-06 | 2026-05-07 |
| Post-Traumatic Growth Following Eye Movement Desensitization and Reprocessing Therapy Versus SSRIs in Patients With Post-Traumatic Stress Disorder EMDR, SSRIs - PTSD - Post Traumatic Stress Disorder | Not applicable | Completed | Asad Ullah Jan | 130 | 2025-05-06 | 2026-05-07 |
| Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs, SSRIs - Postmenopausal Depression, Estrogen | Not applicable | Unknown | Xiao Wang | 40 | 2023-05-12 | 2024-04-10 |
| Intradermal Needle Therapy for Major Depressive Disorder SSRIs, acupuncture, sham acupuncture - Major Depressive Disorder | Not applicable | Unknown | The Third Affiliated hospital of Zhejiang Chinese Medical University | 120 | 2022-05-01 | 2022-04-28 |
| Acupuncture Therapy Based on Biological Specificity of Acupoints for Major Depressive Disorder SSRIs, acupuncture (strong reaction acupoints), acupuncture (weak reaction acupoints) - Major Depressive Disorder | Not applicable | Unknown | The Third Affiliated hospital of Zhejiang Chinese Medical University | 120 | 2022-05-01 | 2022-04-29 |
| Efficacy and Safety of Intradermal Acupuncture for Major Depressive Disorder SSRIs, SIA, AIA - Major Depressive Disorder | Not applicable | Unknown | Xiaomei Shao | 90 | 2022-01-01 | 2022-11-03 |
| A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder SSRIs, SSRI plus Sulforaphane - Major Depressive Disorder | Phase 4 | Unknown | Shanghai Mental Health Center | 150 | 2020-01-01 | 2021-12-08 |
| A Kynurenine Pathway-based Molecular Imaging Study of Individualized Diagnosis and Treatment for Major Depressive Disorder SSRIs - Major Depressive Disorder | Unknown | Shanghai Mental Health Center | 440 | 2019-08-12 | 2019-12-26 | |
| The Gut Microbiota in Obsessive-Compulsive Disorder SSRIs - Obsessive-Compulsive Disorder | Not applicable | Completed | McMaster University | 43 | 2014-11-01 | 2020-09-02 |
| Objective Diagnostic Markers and Personalized Intervention in MDD Patients SSRIs - Depressive Disorder, Major | Not applicable | Unknown | Peking University | 2400 | 2013-11-01 | 2016-05-20 |
| Pharmaco(Epi)Genetic, Proteomic, and Microbiomic Study of Obsessive-Compulsive Disorder SSRIs - Obsessive-Compulsive Disorder | Not applicable | Recruiting | Severance Hospital | 200 | 2013-01-01 | 2024-12-27 |
| Multi-Country Observational Study to Collect the Frequency of Sexual Dysfunction With Antidepressant Treatment, Either With SSRIs or Duals at 8 Weeks and 6 Months SSRIs, Dual antidepressants - Major Depressive Disorder | Completed | Eli Lilly and Company | 1626 | 2007-11-01 | 2009-07-15 |
Depressive Disorder, Major (9) · Obsessive-Compulsive Disorder (2) · Combat Disorders (1) · Depression (1) · Inflammation (1) · Stress Disorders, Post-Traumatic (1)
Asad Ullah Jan (2) · Shanghai Mental Health Center (2) · The Third Affiliated hospital of Zhejiang Chinese Medical University (2) · Eli Lilly and Company (1) · McMaster University (1) · Peking University (1) · Severance Hospital (1) · The Fourth Affiliated Hospital of Zhejiang University School of Medicine (1) · Xiao Wang (1) · Xiaomei Shao (1) · Zhongda Hospital (1)
China (8) · Pakistan (2) · Austria (1) · Canada (1) · Hong Kong (1) · Israel (1) · Lebanon (1) · Malaysia (1) · Mexico (1) · Philippines (1) · Saudi Arabia (1) · Singapore (1) · South Korea (1) · Taiwan (1) · Thailand (1)
Xiaomei Shao, Ph.D (2) · Daihui Peng, MD.PhD. (1) · Michael Van Ameringen, MD, FRCPC (1) · Se Joo Kim, M.D. (1) · Xiaomei M Shao, Ph.D (1) · Xin Yu, MD (1)
PMID 22121927, PMID 27422150, PMID 29664050, PMID 31959583, PMID 32307692, PMID 33874911, PMID 34985583, PMID 37657624, PMID 39433132, PMID 41965575