28 completed, 8 unknown, 5 terminated, 1 active not recruiting. 14 Phase 2, 13 Phase 3, 10 Phase 4, 7 Not applicable, 2 Phase 1.
Follow Solumedrol: new trials by email Literature Review of Solumedrol trials Research Report on Solumedrol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative Colitis Oral Upadacitinib, Intravenous Methylprednisolone, Oral Upadacitinib Placebo - Ulcerative Colitis Acute | Phase 4 | Recruiting | Berinstein, Jeffrey | 110 | 2026-01-16 | 2026-02-02 |
| The Efficacy of Intravenous Pulse in Attaining Remission in Refractory Juvenile Idiopathic Arthritis Solumedrol - Refractory Juvenile Idiopathic Arthritis (Despite 2 DMARDs Still Active) | Phase 3 | Unknown | Sohag University | 215 | 2024-05-01 | 2024-06-17 |
| Pulse Steroid Injection in Refractory Rheumatoid Arthritis Solumedrol - Active Rheumatoid Arthritis | Phase 3 | Unknown | Sohag University | 268 | 2024-05-01 | 2024-06-13 |
| Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method Lumbar medial branch block, Lidocain, Methylprednisolone - Chronic Low-back Pain, Lumbar Facet Joint Syndrome | Not applicable | Unknown | Erasme University Hospital | 40 | 2023-04-21 | 2023-07-05 |
| The Prospective Evaluation of Peri-Operative Glucocorticoid Use in the Management of Cervicofacial Infections of Odontogenic Origin Methylprednisolone - Odontogenic Infection of Jaw (Disorder) | Phase 2 / Phase 3 | Completed | University of Manitoba | 29 | 2022-06-22 | 2023-07-21 |
| Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate to Severe Covid 19 Disease Dexamethasone 2 MG/ML, Methylprednisolone Injection - Covid 19 Disease | Phase 3 | Completed | Fatima Memorial Hospital | 100 | 2020-05-30 | 2020-10-27 |
| Tocilizumab in Active Moderate-severe Graves' Orbitopathy Tocilizumab 20 Mg/mL Intravenous Solution, MethylPREDNISolone Injectable Solution - Graves Ophthalmopathy | Phase 2 | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 56 | 2019-12-18 | 2026-10-23 |
| Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation Belatacept, Tacrolimus, ATG - Lung Transplant Rejection, Antibody-mediated Rejection | Phase 2 | Completed | Washington University School of Medicine | 27 | 2019-12-17 | 2022-11-25 |
| Evaluation of Corticosteroid in Systemic Inflammatory Response Syndrome solumedrol, Dexamethasone phosphate - Systemic Inflammatory Response Syndrome | Phase 4 | Completed | Assiut University | 60 | 2019-09-01 | 2021-06-14 |
| Exploring Durable Remission With Rituximab in Antineutrophil Cytoplasmic Antibody(ANCA)-Associated Vasculitis Rituximab, endoxan, Methylprednisolone - ANCA Associated Vasculitis | Phase 3 | Unknown | Leiden University Medical Center | 100 | 2019-05-03 | 2023-12-14 |
| The Effect of Eltrombopag on the Expression of Platelet Collagen Receptor GPVI in Pediatric ITP. Eltrombopag, conventional - Idiopathic Thrombocytopenic Purpura | Not applicable | Completed | Nayera Hazaa Elsherif | 36 | 2018-08-01 | 2021-10-28 |
| Arrhythmias, Microalbuminuria and Corticosteroids Corticosteroid injection - Corticosteroids Adverse Reaction | Completed | Elza Abdessater | 15 | 2018-01-10 | 2023-11-07 | |
| Prospective Evaluation of Perioperative Steroid Dosing on Postsurgical Edema in Orthognathic Surgery Methylprednisolone - Post-operative Edema, Steroid Use | Phase 4 | Completed | Jean Charles Doucet | 180 | 2018-01-01 | 2021-08-03 |
| Extension of SoluMatrix TM Abiraterone Acetate in Patients Who Completed Study Number CHL-AA-201 SoluMatrix™ Abiraterone Acetate, Methylprednisolone - Prostate Cancer | Phase 3 | Completed | GU Research Network, LLC | 2 | 2016-09-01 | 2020-07-22 |
| Intrathecal Rituximab in Progressive Multiple Sclerosis Rituximab IT, methylprednisolone IV, Rituximab IV - Multiple Sclerosis, Chronic Progressive, Nervous System Diseases | Phase 2 | Completed | Centre Hospitalier de PAU | 10 | 2015-11-30 | 2019-10-03 |
| Steroids in Fulminant Hepatitis A in the Pediatric Age Group prednisolone, methylprednisolone - Fulminant Hepatic Failure | Phase 4 | Completed | National Liver Institute, Egypt | 33 | 2015-01-01 | 2018-12-17 |
| Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation Anti-Thymocyte Globulin - Rabbit, darTreg Infusion, Everolimus - Liver Transplantation | Phase 1 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 15 | 2014-12-17 | 2020-09-22 |
| Open-Label Study to Evaluate the Efficacy of ECP in Secondary Progressive Multiple Sclerosis SoluMedrol, Extracorporeal Photopheresis - Secondary Progressive Multiple Sclerosis | Not applicable | Terminated | University of Utah | 13 | 2014-10-01 | 2019-08-14 |
| Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA) Liposomal bupivacaine, Standard of care analgesia - Osteoarthritis, Knee, Osteoarthritis, Hip | Not applicable | Completed | OhioHealth | 211 | 2014-07-01 | 2016-10-21 |
| Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children Methylprednisolone Arm, Sterile Saline Arm - Acute Lung Injury, Acute Respiratory Distress Syndrome | Phase 2 | Withdrawn | Universidade Federal do Rio de Janeiro | 2014-01-01 | 2020-07-10 |
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Leukemia (3) · Purpura, Thrombocytopenic, Idiopathic (3) · Glomerulonephritis, IGA (2) · Graves Ophthalmopathy (2) · Multiple Sclerosis (2) · Multiple Sclerosis, Chronic Progressive (2) · Neoplasms (2) · Proteinuria (2) · Respiratory Distress Syndrome (2) · Acute Lung Injury (1) · Albuminuria (1) · Amyotrophic Lateral Sclerosis (1) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (1) · Arrhythmias, Cardiac (1) · Arthritis, Juvenile (1)
Stanford University (4) · A. Manzoni Hospital (2) · Sohag University (2) · Washington University School of Medicine (2) · Ain Shams University (1) · Assiut University (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Berinstein, Jeffrey (1) · Cedars-Sinai Medical Center (1) · Centre Hospitalier de PAU (1) · Elza Abdessater (1) · Emory University (1) · Erasme University Hospital (1) · Fatima Memorial Hospital (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1)
United States (20) · Egypt (6) · Canada (4) · Belgium (3) · Italy (3) · France (2) · Brazil (1) · Netherlands (1) · Pakistan (1) · Sweden (1) · Switzerland (1) · Taiwan (1)
Robert Lowsky (2) · Alaa F Fathy, researcher (1) · Antonello Pani, MD (1) · Arnaldo P Barbosa (1) · Arzinda F Syeda, MBBS, FCPS (1) · Azza AG Tantawy, MD (1) · Benjamin Segal, MD (1) · Ceib Philllips, PhD, MPH (1) · Christina N Fournier, MD (1) · Claudio Ponticelli, MD (1) · Claudio Pozzi, MD (1) · Daniel Couriel, MD (1) · Daniel Kantor, MD (1)
PMID 11919310, PMID 12359731, PMID 17452226, PMID 19005182, PMID 20148887, PMID 20671616, PMID 22563089, PMID 23361904, PMID 23369458, PMID 23587468, PMID 23774314, PMID 23870160, PMID 24674813, PMID 26231455, PMID 26477577, PMID 2665875, PMID 26688484, PMID 27403440, PMID 28422025, PMID 28627134, PMID 29308669, PMID 31206501, PMID 31806605, PMID 32282882, PMID 33277746, PMID 33649098, PMID 34778952, PMID 36130755, PMID 37899481
P01CA049605 (1), R01DE005215 (1), R34AI095135 (1), U01AI110658 (1)