27 completed, 14 terminated, 6 active not recruiting, 3 withdrawn. 51 Phase 2, 5 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 51 | Completed 27, Terminated 14, Active not recruiting 6, Withdrawn 3, Not yet recruiting 1 |
| Phase 3 | 5 | Active not recruiting 3, Completed 2 |
| Phase 1 | 2 | Completed 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer Isopropyl Alcohol, Placebo, Questionnaire Administration - Malignant Neoplasm | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 112 | 2026-11-05 | 2026-05-27 |
| Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer Celecoxib, Placebo, Quality-of-Life Assessment - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Terminated | University of Utah | 13 | 2019-11-27 | 2025-02-12 |
| Treatment of Central Retinal Vein Occlusion Using Stem Cells Study Autologous Bone Marrow CD34+ Stem Cells, Sham Therapy - Central Retinal Vein Occlusion | Phase 1 / Phase 2 | Completed | The Emmes Company, LLC | 16 | 2019-10-22 | 2024-12-02 |
| Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care Haloperidol, Lorazepam, Placebo - Delirium, Locally Advanced Malignant Neoplasm | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 110 | 2019-07-17 | 2026-06-15 |
| Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer Exercise Intervention, Methylphenidate, Placebo - Prostate Carcinoma | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 200 | 2019-03-25 | 2026-10-07 |
| Study Evaluating The Role of ClO2 on Mucositis for Pt. Undergoing Head/Neck Radiotherapy Chlorine Dioxide Sterilization, Laboratory Biomarker Analysis, Placebo - Head and Neck Carcinoma | Phase 2 | Terminated | University of Arizona | 14 | 2019-02-14 | 2024-03-20 |
| Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Reducing CMV Related Complications in Patients With Blood Cancer Undergoing Donor Stem Cell Transplant Multi-antigen CMV-Modified Vaccinia Ankara Vaccine, Laboratory Biomarker Analysis, Placebo - Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia in Remission | Phase 2 | Withdrawn | City of Hope Medical Center | 2018-12-01 | 2018-11-21 | |
| Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer Anamorelin Hydrochloride, Placebo, Questionnaire Administration - Anorexia, Lung Non-Small Cell Carcinoma | Phase 2 / Phase 3 | Active not recruiting | M.D. Anderson Cancer Center | 25 | 2018-11-27 | 2026-10-06 |
| Arginine in Treating Patients With Anti-VEGF Induced Kidney Injury Arginine, Placebo - Drug-Induced Nephropathy, Hypertension | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2018-10-23 | 2019-05-21 | |
| ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment Laboratory Biomarker Analysis, Metformide Hydrochloride/Pioglitazone Hydrochloride Extended-Release Tablet, Pharmacological Study - Oral Cavity Neoplasm, Oropharyngeal Neoplasm | Phase 2 | Terminated | National Cancer Institute (NCI) | 6 | 2018-05-31 | 2023-03-08 |
| Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast Afimoxifene, Laboratory Biomarker Analysis, Placebo - Mammographically Dense Breast | Phase 2 | Completed | M.D. Anderson Cancer Center | 194 | 2018-01-30 | 2024-02-22 |
| Dexamethasone in Controlling Dyspnea in Patients With Cancer Dexamethasone, Placebo, Questionnaire Administration - Dyspnea, Malignant Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 135 | 2017-12-04 | 2026-10-16 |
| IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3 Cyclophosphamide, Indomethacin, IRX-2 - Cervical Squamous Cell Carcinoma In Situ, Vulvar High Grade Squamous Intraepithelial Lesion | Phase 2 | Terminated | University of Southern California | 10 | 2017-11-08 | 2025-04-13 |
| Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer Anti-OX40 Antibody PF-04518600, Axitinib, Laboratory Biomarker Analysis - Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Cancer | Phase 2 | Active not recruiting | University of Southern California | 62 | 2017-07-19 | 2026-06-03 |
| Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer Atezolizumab, Bevacizumab, Capecitabine - Metastatic Colorectal Carcinoma, Recurrent Colorectal Carcinoma | Phase 2 | Completed | Academic and Community Cancer Research United | 133 | 2017-07-07 | 2024-08-23 |
| Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast Afimoxifene, Laboratory Biomarker Analysis, Placebo - Ductal Breast Carcinoma In Situ, Estrogen Receptor Positive | Phase 2 | Completed | Northwestern University | 100 | 2017-05-31 | 2024-12-18 |
| Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer Ibuprofen, Placebo, Questionnaire Administration - Cognitive Impairment, Malignant Neoplasm | Phase 2 | Completed | University of Rochester NCORP Research Base | 87 | 2017-05-26 | 2023-09-25 |
| Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With Cancer Netupitant, Palonosetron, Palonosetron Hydrochloride - Malignant Neoplasm, Nausea | Phase 2 / Phase 3 | Completed | M.D. Anderson Cancer Center | 53 | 2017-05-03 | 2023-10-17 |
| Ethyl Icosapentate and Physical Activity in Treating Fatigue in Patients With Advanced Cancer Ethyl Icosapentate, Exercise Intervention, Laboratory Biomarker Analysis - Advanced Malignant Neoplasm, Fatigue | Phase 2 | Terminated | M.D. Anderson Cancer Center | 2 | 2017-03-16 | 2021-06-10 |
| The PROMISE Study: Duavee in Women With DCIS Conjugated Estrogens/Bazedoxifene, Laboratory Biomarker Analysis, Pharmacological Study - Ductal Breast Carcinoma In Situ, Postmenopausal | Phase 2 | Completed | Northwestern University | 142 | 2017-01-01 | 2025-01-28 |
Showing 20 of 51. Sign in to see all of them.
Prostatic Neoplasms (6) · Neoplasms (5) · Breast Neoplasms (4) · Carcinoma, Intraductal, Noninfiltrating (3) · Carcinoma, Non-Small-Cell Lung (3) · Ovarian Neoplasms (3) · Squamous Cell Carcinoma of Head and Neck (3) · Urinary Bladder Neoplasms (3) · Breast Carcinoma In Situ (2) · Colorectal Neoplasms (2) · Fallopian Tube Neoplasms (2) · Hodgkin Disease (2) · Hypopharyngeal Neoplasms (2) · Laryngeal Neoplasms (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2)
National Cancer Institute (NCI) (13) · M.D. Anderson Cancer Center (11) · Academic and Community Cancer Research United (5) · City of Hope Medical Center (2) · Gynecologic Oncology Group (2) · Northwestern University (2) · Roswell Park Cancer Institute (2) · University of Southern California (2) · University of Washington (2) · Children's Oncology Group (1) · GOG Foundation (1) · Gary Morrow (1) · Mayo Clinic (1) · Rutgers, The State University of New Jersey (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
United States (49) · Brazil (1) · Canada (1) · Italy (1) · Puerto Rico (1)
David Hui (3) · Ryotaro Nakamura, MD (2) · Sriram Yennu (2) · Tracy Downs (2) · Aminah Jatoi (1) · Ayca Gucalp (1) · Banu Arun, MD (1) · Bernardo Bonanni (1) · Biren Saraiya, MD (1) · Channing Paller, MD (1) · Charles Loprinzi (1) · David F Jarrard (1) · David Jarrard (1) · Debra Richardson (1) · Eric Winquist (1)
PMID 37185961, PMID 27760761, PMID 28285845, PMID 29242937, PMID 29802852, PMID 32040960, PMID 33388382, PMID 35179586, PMID 35380713, PMID 36087590, PMID 36636059, PMID 36889516, PMID 36912792, PMID 37870954, PMID 38197040, PMID 39076107, PMID 39187984, PMID 40742738, PMID 42018190
P30CA015083 (7), P30CA014520 (5), N01CN00033 (3), N01CN00034 (3), N01CN35153 (3), P30CA016672 (3), P30CA006973 (2), P30CA014089 (2), P30CA015704 (2), P30CA016056 (2), P30CA023074 (2), P30CA060553 (2), U10CA027469 (2), U10CA101165 (2), U10CA180868 (2)