7 completed, 2 enrolling by invitation, 2 not yet recruiting, 1 recruiting. 9 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 5, Enrolling by invitation 2, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 3 | Completed 2, Not yet recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Rutin: new trials by email Literature Review of Rutin trials Research Report on Rutin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rutin and Ascorbic Acid for Prevention of Vancomycin-Induced Nephrotoxicity in Adult Patients" - a Clinical Trial Protocol Evaluating Whether Combined Rutin/Vitamin C Supplementation Reduces Kidney Toxicity From Vancomycin, Compared to Vitamin C Alone and Control. Rutin + Ascorbic Acid (RUTA C60®), Ascorbic Acid (C-Retard®) - Nephrotoxicity, Acute Kidney Injuries | Not applicable | Enrolling by invitation | Ain Shams University | 120 | 2026-10-01 | 2026-10-14 |
| The Effect of a Peer-Based Instructional Disaster Education Program on Disaster Preparedness Beliefs and Disaster Attitudes of First Aid and Emergency Program Students peer-supported disaster preparedness training, Rutin - The Aim is to Strengthen Disaster Preparedness Knowledge and Skills Through Peer Interaction | Not applicable | Enrolling by invitation | Selcuk University | 75 | 2026-05-15 | 2026-05-27 |
| Tinnitus and Treatment With umPEA-LUT PEA-LUT 2 sachet day, Placebo, umPEALUT + Rutin + 5 hTp - Tinnitus, Neuroinflammation | Not applicable | Not yet recruiting | University of Campania Luigi Vanvitelli | 100 | 2026-04-20 | 2026-02-06 |
| Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) Rutin + Vitamin C, Vitamin C 500mg, Lifestyle Intervention - NAFLD | Phase 2 | Not yet recruiting | Ain Shams University | 120 | 2026-01-01 | 2025-12-30 |
| The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain Trypsin, Bromelain and Rutoside, Diclofenac Potassium 50mg Tab, Prednisolone Oral Tablet - Symptomatic Irreversible Pulpitis | Not applicable | Completed | Cairo University | 124 | 2025-06-15 | 2026-07-22 |
| Pilot Study on Rutin Combined With Tislelizumab and GC (Gemcitabine and Cisplatin) as Neoadjuvant Therapy for Platinum-refractory Muscle-invasive Bladder Cancer Rutin, Gemcitabine, Cisplatin, Tislelizumab - Muscle Invasive Bladder Cancer | Phase 1 | Recruiting | First Affiliated Hospital of Chongqing Medical University | 10 | 2025-05-01 | 2025-04-10 |
| Effect of Rutin on Inflammation Pathways in Ulcerative Colitis Patients Rutin 500 MG Oral Tablet, Fecal Calprotectin, Placebo - Ulcerative Colitis | Phase 2 | Completed | Benha University | 60 | 2025-02-22 | 2026-01-27 |
| Rutin Therapy Role in Reducing Ulcerative Colitis Severity Rutin 500 MG, Placebo, fecal calprotectin - Ulcerative Colitis | Not applicable | Completed | Benha University | 60 | 2024-11-01 | 2025-08-29 |
| Effects of Rutin on Oxidative Stress, Inflammatory Markers, and Blood Flow Velocity During Cycling 40km Time Trial Performance Placebo (Placebo trial), Rutin (Rutin trial) - Healthly Volunteers | Not applicable | Completed | China Medical University Hospital | 12 | 2024-10-30 | 2026-04-08 |
| The Effect of Music in Alzheimer's Patients Music therapy - Alzheimer Disease | Not applicable | Completed | Eskisehir Osmangazi University | 30 | 2018-04-16 | 2021-11-18 |
| Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients Rutin in combination with Vitamin C, Vitamin C - Type 2 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Ain Shams University | 53 | 2018-02-24 | 2018-05-16 |
| Sulindac and Plant Compounds in Preventing Colon Cancer curcumin, rutin, quercetin - Colorectal Cancer | Not applicable | Terminated | University of Medicine and Dentistry of New Jersey | 1996-08-01 | 2011-01-27 | |
| Retinal Nerve Fibres Layers Thickness Study in Glaucomatous Patients forskolin, rutin and vitamins B1 and B2 - Glaucoma | Not applicable | Completed | University of Roma La Sapienza | 2010-12-06 |
Colitis, Ulcerative (2) · Acute Kidney Injury (1) · Alzheimer Disease (1) · Behavior (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Diabetes Mellitus, Type 2 (1) · Glaucoma (1) · Insulin Resistance (1) · Neuroinflammatory Diseases (1) · Non-alcoholic Fatty Liver Disease (1) · Tinnitus (1)
Ain Shams University (3) · Benha University (2) · Cairo University (1) · China Medical University Hospital (1) · Eskisehir Osmangazi University (1) · First Affiliated Hospital of Chongqing Medical University (1) · Selcuk University (1) · University of Campania Luigi Vanvitelli (1) · University of Medicine and Dentistry of New Jersey (1) · University of Roma La Sapienza (1)
Egypt (6) · Italy (2) · Turkey (Türkiye) (2) · China (1) · Taiwan (1) · United States (1)
Arianna Di Stadio, MD, PhD, MSc (1) · Jung-Piao Tsao (1) · Maha Nasr (1) · Sara M Zaki, Professor (1) · Steven J. Shiff, MD (1) · Xin Gou, Professor (1)
PMID 12238249, PMID 17416295, PMID 17956787, PMID 19561730, PMID 22931904, PMID 25190255, PMID 25862619, PMID 25997584, PMID 26547700, PMID 28885581, PMID 30015600, PMID 30058696, PMID 30261653, PMID 30469326, PMID 30538616, PMID 31042571, PMID 31842394, PMID 31987106, PMID 32471239, PMID 34282564, PMID 34768526, PMID 42473278, PMID 5642369, PMID 6743061
P30CA016056 (1)