rovalpituzumab tesirine: Clinical Trials

13 trials of rovalpituzumab tesirine, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

7 completed, 4 terminated, 1 no longer available, 1 withdrawn. 7 Phase 1, 5 Phase 2, 3 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 17Completed 4, Terminated 3
Phase 25Completed 3, Terminated 2
Phase 33Completed 1, Terminated 1, Withdrawn 1

Follow rovalpituzumab tesirine: new trials by email Literature Review of rovalpituzumab tesirine trials Research Report on rovalpituzumab tesirine

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Long-Term Study of Rovalpituzumab Tesirine
rovalpituzumab tesirine - Cancer
Phase 2CompletedAbbVie32018-09-102021-01-05
Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer
Dexamethasone, Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 3WithdrawnAbbVie2018-03-152018-12-26
A Study on the Safety and Tolerability of Rovalpituzumab Tesirine in Japanese Patients With Advanced, Recurrent Small Cell Lung Cancer
Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 1CompletedAbbVie292017-04-282021-08-03
Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)
Rovalpituzumab tesirine, Topotecan, Dexamethasone - Small Cell Lung Cancer
Phase 3CompletedAbbVie4442017-04-112021-02-23
A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer
Ipilimumab, Nivolumab, Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 1 / Phase 2TerminatedAbbVie422017-03-302020-07-17
A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
Placebo for dexamethasone, Placebo for rovalpituzumab tesirine, Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 3TerminatedAbbVie7482017-02-072021-07-29
A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
Venetoclax, Rovalpituzumab Tesirine, ABBV-181 - Advanced Solid Tumors
Phase 1CompletedAbbVie1822016-12-142022-04-14
A Study of Rovalpituzumab Tesirine (SC16LD6.5) in the Frontline Treatment of Patients With Extensive Stage Small Cell Lung Cancer
Rovalpituzumab Tesirine, Cisplatin, Etoposide - Small Cell Lung Cancer
Phase 1TerminatedAbbVie282016-10-012020-03-12
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
Rovalpituzumab tesirine, Dexamethasone - Malignant Melanoma, Medullary Thyroid Cancer
Phase 1 / Phase 2TerminatedAbbVie2002016-09-232020-10-19
A Study of Rovalpituzumab Tesirine to Study Cardiac Ventricular Repolarization in Subjects With Small Cell Lung Cancer
Rovalpituzumab Tesirine - Small Cell Lung Carcinoma
Phase 1CompletedStemcentrx462016-09-012018-09-24
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer
Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 2CompletedAbbVie3422016-01-252021-07-30
Rovalpituzumab Tesirine (SC16LD6.5) in Recurrent Small Cell Lung Cancer
Rovalpituzumab tesirine (SC16LD6.5) - Recurrent Small Cell Lung Cancer
Phase 1 / Phase 2CompletedStemcentrx822013-07-012018-08-09
Expanded Access to Rovalpituzumab Tesirine
rovalpituzumab tesirine - Small Cell Lung Cancer
No longer availableAbbVie2019-09-10

Conditions studied

Small Cell Lung Carcinoma (11)  ·  Neoplasms (6)  ·  Carcinoma, Hepatocellular (1)  ·  Carcinoma, Medullary (1)  ·  Carcinoma, Merkel Cell (1)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Cholangiocarcinoma (1)  ·  Glioblastoma (1)  ·  Head and Neck Neoplasms (1)  ·  Melanoma (1)  ·  Mesothelioma (1)  ·  Neoplasm Metastasis (1)  ·  Ovarian Neoplasms (1)  ·  Recurrence (1)  ·  Stomach Neoplasms (1)

Sponsors

AbbVie (11)  ·  Stemcentrx (2)

Countries

United States (10)  ·  Canada (5)  ·  Australia (4)  ·  France (4)  ·  Germany (4)  ·  Japan (4)  ·  Spain (4)  ·  Belgium (3)  ·  Brazil (3)  ·  Italy (3)  ·  Sweden (3)  ·  Taiwan (3)  ·  United Kingdom (3)  ·  Austria (2)  ·  Belarus (2)

Top investigators

Daniel Da Costa, PharmD (1)  ·  Donald Strickland, MD (1)

Results publications

PMID 29290251, PMID 27932068, PMID 32372416, PMID 32770720, PMID 34216247, PMID 34329846, PMID 35034046

NIH funding

2016 (4), 2015 (1), 2017 (1)