rovalpituzumab tesirine: Clinical Trials

5 trials of rovalpituzumab tesirine, newest first

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3 completed, 2 terminated. 5 Phase 2, 3 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 25Completed 3, Terminated 2
Phase 13Terminated 2, Completed 1

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Trials (filtered) newest first · largest first

All 5 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Long-Term Study of Rovalpituzumab Tesirine
rovalpituzumab tesirine - Cancer
Phase 2CompletedAbbVie32018-09-102021-01-05
A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer
Ipilimumab, Nivolumab, Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 1 / Phase 2TerminatedAbbVie422017-03-302020-07-17
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
Rovalpituzumab tesirine, Dexamethasone - Malignant Melanoma, Medullary Thyroid Cancer
Phase 1 / Phase 2TerminatedAbbVie2002016-09-232020-10-19
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer
Rovalpituzumab tesirine - Small Cell Lung Cancer
Phase 2CompletedAbbVie3422016-01-252021-07-30
Rovalpituzumab Tesirine (SC16LD6.5) in Recurrent Small Cell Lung Cancer
Rovalpituzumab tesirine (SC16LD6.5) - Recurrent Small Cell Lung Cancer
Phase 1 / Phase 2CompletedStemcentrx822013-07-012018-08-09

Conditions studied

Small Cell Lung Carcinoma (3)  ·  Neoplasms (2)  ·  Carcinoma, Medullary (1)  ·  Glioblastoma (1)  ·  Melanoma (1)  ·  Recurrence (1)

Sponsors

AbbVie (4)  ·  Stemcentrx (1)

Countries

United States (4)  ·  France (1)  ·  Germany (1)  ·  Italy (1)  ·  Spain (1)

Top investigators

Donald Strickland, MD (1)

Results publications

PMID 27932068, PMID 32372416

NIH funding

2015 (1), 2016 (1)