6 completed, 1 terminated. 7 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 6, Terminated 1 |
Follow rilonacept: new trials by email Literature Review of rilonacept trials Research Report on rilonacept
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis Rilonacept, Placebo - Recurrent Pericarditis | Phase 3 | Completed | Kiniksa Pharmaceuticals (UK), Ltd. | 86 | 2019-01-07 | 2023-09-06 |
| Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares Rilonacept, Placebo, Allopurinol - Gout | Phase 3 | Terminated | Regeneron Pharmaceuticals | 220 | 2011-11-01 | 2017-07-18 |
| PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2) Placebo, Rilonacept - Gout | Phase 3 | Completed | Regeneron Pharmaceuticals | 248 | 2009-07-01 | 2017-04-28 |
| Review of Safety Using Rilonacept in Preventing Gout Exacerbations (RE-SURGE) Rilonacept, Placebo - Gout | Phase 3 | Completed | Regeneron Pharmaceuticals | 1315 | 2009-03-01 | 2017-04-28 |
| Study Utilizing Rilonacept in Gout Exacerbations Rilonacept, Indomethacin, Placebo (for Indomethacin) - Acute Gout Flare | Phase 3 | Completed | Regeneron Pharmaceuticals | 225 | 2009-03-01 | 2017-04-28 |
| PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1 Placebo, Rilonacept 80 mg, Rilonacept 160 mg - Intercritical Gout | Phase 3 | Completed | Regeneron Pharmaceuticals | 241 | 2009-02-01 | 2017-04-28 |
| Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS) rilonacept 160 mg, Placebo - Familial Cold Autoinflammatory Syndrome (FCAS), Familial Cold Urticaria | Phase 3 | Completed | Regeneron Pharmaceuticals | 104 | 2005-12-01 | 2011-12-06 |
Genetic Diseases, Inborn (5) · Gout (5) · Arthritis (4) · Joint Diseases (4) · Metabolic Diseases (4) · Metabolism, Inborn Errors (4) · Musculoskeletal Diseases (4) · Purine-Pyrimidine Metabolism, Inborn Errors (4) · Rheumatic Diseases (4) · Cryopyrin-Associated Periodic Syndromes (1) · Pericarditis (1)
Regeneron Pharmaceuticals (6) · Kiniksa Pharmaceuticals (UK), Ltd. (1)
United States (6) · Germany (2) · India (2) · Indonesia (2) · South Africa (2) · Taiwan (2) · Australia (1) · Canada (1) · Israel (1) · Italy (1)
Robert Evans, PharmD (3) · Robert Evans, PharmD. (1)
PMID 18668535, PMID 22549879, PMID 23031624, PMID 23375025, PMID 23485476, PMID 25028379, PMID 32866928, PMID 36250662, PMID 36316102, PMID 37163222, PMID 38471825, PMID 39022168, PMID 39044797
2008 (1), 2018 (1)