Rigosertib: Clinical Trials

7 trials of Rigosertib, newest first

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7 completed. 7 Phase 2, 3 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 27Completed 7
Phase 13Completed 3

Follow Rigosertib: new trials by email Literature Review of Rigosertib trials Research Report on Rigosertib

Trials (filtered) newest first · largest first

All 7 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment
Rigosertib, Nivolumab - Non-small Cell Lung Cancer, Adenocarcinoma
Phase 1 / Phase 2CompletedIcahn School of Medicine at Mount Sinai252020-06-292024-05-09
Oral Rigosertib for Squamous Cell Carcinoma
rigosertib - Head and Neck Squamous Cell Carcinoma, Anal Squamous Cell Carcinoma
Phase 2CompletedTraws Pharma, Inc.642013-03-012017-06-26
Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome
rigosertib - Myelodysplastic Syndrome, MDS
Phase 2CompletedTraws Pharma, Inc.822012-05-012017-06-26
Safety and Efficacy of 72-hour and 120-hour Infusion of Rigosertib in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL)
rigosertib - Acute Myelocytic Leukemia, Acute Lymphocytic Leukemia
Phase 1 / Phase 2CompletedTraws Pharma, Inc.302010-07-012017-06-26
Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk
ON 01910.Na - Myelodysplastic Syndrome
Phase 2CompletedTraws Pharma, Inc.142009-05-012017-06-26
Effect of 2-h Infusion of ON 01910.Na in Ovarian Cancer Patients
ON 01910.Na - Ovarian Cancer
Phase 2CompletedTraws Pharma, Inc.12009-03-012017-07-21
Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AML
ON 01910.Na - Myelodysplastic Syndrome, Acute Myeloid Leukemia
Phase 1 / Phase 2CompletedTraws Pharma, Inc.362009-01-012017-06-26

Conditions studied

Myelodysplastic Syndromes (3)  ·  Chromosome 8, trisomy (2)  ·  Leukemia, Myeloid, Acute (2)  ·  Adenocarcinoma (1)  ·  Anemia, Refractory (1)  ·  Anus Neoplasms (1)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Carcinoma, Squamous Cell (1)  ·  Cytopenia (1)  ·  Esophageal Squamous Cell Carcinoma (1)  ·  Head and Neck Neoplasms (1)  ·  Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1)  ·  Myeloproliferative Disorders (1)  ·  Neoplasm Metastasis (1)  ·  Neoplasms (1)

Sponsors

Traws Pharma, Inc. (6)  ·  Icahn School of Medicine at Mount Sinai (1)

Countries

United States (7)

Top investigators

Azra Raza, MD (1)  ·  Gregory P. Sutton, MD (1)  ·  Jorge Cortes, MD (1)  ·  Michael Kurman, MD (1)  ·  Peter L. Greenberg, MD (1)  ·  Rajwanth Veluswamy, MD, MSCR (1)  ·  Steven M. Fruchtman, MD (1)

Results publications

PMID 27400247, PMID 21924492, PMID 24777753