5 completed, 3 active not recruiting, 3 unknown, 1 recruiting. 12 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 5, Active not recruiting 3, Unknown 3, Recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow RFA: new trials by email Literature Review of RFA trials Research Report on RFA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus Biopsy Procedure, Biospecimen Collection, Endoscopic Procedure - Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2026-06-23 | 2026-09-14 |
| Local Treatment in ER-positive/HER2-negative Oligo-metastatic Breast Cancer Surgical resection, Stereotactic body radiotherapy, Radiofrequency ablation - Breast Cancer, Recurrent Breast Cancer | Phase 2 | Unknown | Gangnam Severance Hospital | 110 | 2018-08-01 | 2019-02-15 |
| A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC) Durvalumab, Tremelimumab, Trans-arterial Catheter Chemoembolization (TACE) - Biliary Tract Neoplasms, Liver Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 54 | 2016-07-05 | 2023-03-28 |
| Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Cervical Cancer Radiofrequency ablation, Cytokine-induced killer cells - Cervical Cancer | Phase 2 | Active not recruiting | The First People's Hospital of Changzhou | 10 | 2015-07-01 | 2016-02-23 |
| Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Ovarian Carcinoma Radiofrequency ablation, Cytokine-induced killer cells - Ovarian Carcinoma | Phase 2 | Active not recruiting | The First People's Hospital of Changzhou | 50 | 2015-07-01 | 2016-02-23 |
| RFA Combined With Oxaliplatin + 5-FluoroUracil/LeucoVorin (5-FU/LV) (FOLFOX4) for Recurrent HCC RFA, Oxaliplatin, 5-Fluorouracil/Leucovorin - Hepatocellular Carcinoma | Phase 2 | Unknown | Sun Yat-sen University | 28 | 2015-04-01 | 2015-04-27 |
| Tremelimumab With Chemoembolization or Ablation for Liver Cancer Tremelimumab, RFA, TACE - Heptocellular Cancer, Biliary Tract Neoplasms | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 61 | 2013-05-02 | 2019-12-10 |
| Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Cholangiocarcinoma Radiofrequency ablation, Cytokine-induced killer cells - Cholangiocarcinoma | Phase 2 / Phase 3 | Active not recruiting | The First People's Hospital of Changzhou | 50 | 2012-07-01 | 2017-08-01 |
| Combine TACE and RFA Versus RFA Monotherapy in Unilobar HCC of 3.1 to 7 cm Patient Transcatheter Arterial Chemoembolization, Radiofrequency ablation, Doxorubicin - Hepatocellular Carcinoma | Phase 2 | Unknown | Shi-Ming Lin | 60 | 2012-01-01 | 2013-05-23 |
| Sorafenib and Micro-therapy Guided by Primovist Enhanced MRI in Patients With Inoperable Liver Cancer RFA, Radioembolization (SIRT) - Hepatocellular Carcinoma | Phase 2 | Completed | University of Magdeburg | 529 | 2010-12-01 | 2019-05-31 |
| Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for Colorectal Cancer Liver Metastases Radiofrequency ablation, Cytokine-induced killer cells - Colorectal Cancer | Phase 2 / Phase 3 | Completed | The First People's Hospital of Changzhou | 60 | 2010-01-01 | 2015-04-17 |
| Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular Cancer Sorafenib, radiofrequency ablation - Hepatocellular Cancer | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 20 | 2009-06-01 | 2023-06-13 |
Carcinoma, Hepatocellular (5) · Liver Neoplasms (4) · Biliary Tract Neoplasms (2) · Cholangiocarcinoma (2) · Adenocarcinoma Of Esophagus (1) · Barrett Esophagus (1) · Bile Duct Neoplasms (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Diabetes Mellitus, Insulin-Dependent, 12 (1) · Ovarian Neoplasms (1) · Uterine Cervical Neoplasms (1)
The First People's Hospital of Changzhou (4) · National Cancer Institute (NCI) (3) · Beth Israel Deaconess Medical Center (1) · Gangnam Severance Hospital (1) · Shi-Ming Lin (1) · Sun Yat-sen University (1) · University of Magdeburg (1)
United States (4) · China (3) · Germany (1) · South Korea (1) · Taiwan (1)
Changping Wu, M.D. (2) · Tim F Greten, M.D. (2) · Ajay Bansal, MD (1) · Andrea Bullock, MD, MPH (1) · Jens Ricke, Prof. Dr. (1) · Joon Jeong, Ph.D. (1) · Peter Malfertheiner, Prof. Dr. (1) · Shi-Ming Lin, MD (1)
PMID 27816492, PMID 28923358, PMID 30578687, PMID 30688989, PMID 34297268, PMID 34454995, PMID 36968218, PMID 38205877, PMID 39965889, PMID 41822100
K23CA139005 (1), P30CA046592 (1), UG1CA242632 (1)