34 unknown, 30 completed, 6 active not recruiting, 5 recruiting. 39 Not applicable, 13 Phase 4, 12 Phase 2, 6 Phase 3, 2 Phase 1.
Follow RFA: new trials by email Literature Review of RFA trials Research Report on RFA
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus Biopsy Procedure, Biospecimen Collection, Endoscopic Procedure - Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8 | Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2026-06-23 | 2026-09-14 |
| Percutaneous Thermo-ablation for the Treatment of Prostate Cancer Oligometastatasis (TA-P-OLIM) Thermal ablation - Oligometastatic Prostate Cancer (OMPC), Prostate Cancer (Adenocarcinoma) | Withdrawn | University Hospital, Ghent | 2026-05-10 | 2026-05-13 | ||
| Percutaneous Thermo-ablation for the Treatment of Benign Thyroid Nodules Percutaneous radiofrequency ablation - Benign Thyroid Nodule | Recruiting | University Hospital, Ghent | 100 | 2026-03-03 | 2026-08-26 | |
| Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA) Argon plasma coagulation (APC), RFA - GERD (Gastroesophageal Reflux Disease), Throat Disorders | Not applicable | Active not recruiting | Assaf-Harofeh Medical Center | 72 | 2025-11-01 | 2025-12-05 |
| Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma Intraductal biliary radiofrequency ablation - Cholangiocarcinoma, Klatskin Tumor | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 130 | 2024-08-30 | 2026-09-09 |
| Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT Radiofrequency ablation alone, Microwave ablation - Ablation Techniques, RFA, Ablation Treatment | Not applicable | Active not recruiting | The University of Hong Kong | 50 | 2023-12-05 | 2026-09-21 |
| A Study of Endobiliary Radiofrequency Ablation in Malignant Biliary Obstructions Temperature-sensitive radiofrequency ablation, No intervention - Biliary Stricture | Completed | Mayo Clinic | 176 | 2023-04-13 | 2025-02-27 | |
| Radiofrequency Ablation for the Treatment of Benign Thyroid Nodules: A Prospective Study Radiofrequency ablation alone - Benign Thyroid Nodules | Not applicable | Active not recruiting | Hue University of Medicine and Pharmacy | 106 | 2023-02-10 | 2025-12-16 |
| Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma RFA, PDT, RFA combined with PDT - Extrahepatic Cholangiocarcinoma, Bile Duct Cancer | Not applicable | Unknown | First People's Hospital of Hangzhou | 70 | 2023-01-01 | 2023-02-21 |
| Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule Quality-of-Life Assessment, Radiofrequency Ablation - Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma | Not applicable | Terminated | M.D. Anderson Cancer Center | 1 | 2022-08-29 | 2025-04-02 |
| Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules Radiofrequency ablation, Radioactive iodine - Thyroid Nodule, Toxic or With Hyperthyroidism, Autonomous Thyroid Function | Phase 3 | Terminated | Rijnstate Hospital | 40 | 2021-11-17 | 2025-07-17 |
| Radiofrequency Ablation Plus Systematic Neoadjuvant Therapy for Recurrent Hepatocellular Carcinoma (RANT Study) Tislelizumab/Sintilimab+Lenvatinib/Bevacizumab, RFA - Hepatocellular Carcinoma Recurrent | Not applicable | Unknown | Southwest Hospital, China | 160 | 2021-11-01 | 2022-03-14 |
| RADIO FREQUENCY ABLATION IN UNRESECTABLE MALIGNANT BILIARY OBSTRUCTION Radio frequency ablation - Bile Duct Neoplasms, Gall Bladder Carcinoma | Unknown | Asian Institute of Gastroenterology, India | 50 | 2021-06-10 | 2022-04-11 | |
| Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain Alcohol injection, Radiofrequency Ablation - Malignancy, Pain Management | Phase 4 | Unknown | The University of Hong Kong | 54 | 2021-03-01 | 2021-03-22 |
| Radiofrequency Ablation Combined With Melatonin in the Treatment of Stage IA NSCLC RFA - NSCLC and Theropy | Not applicable | Unknown | Shanghai 10th People's Hospital | 260 | 2021-01-01 | 2020-08-28 |
| Thermal Ablation of Cervical Metastases From Thyroid Carcinoma Laser ablation, Cryoablation, Radiofrequency ablation - Thyroid Neoplasia, Well-Differentiated Thyroid Cancer | Not applicable | Completed | Instituto do Cancer do Estado de São Paulo | 84 | 2020-12-22 | 2026-09-22 |
| Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors iNeo-Vac-P01, GM-CSF, PD-1 - Advanced Malignant Solid Tumor | Phase 1 | Unknown | Sir Run Run Shaw Hospital | 30 | 2020-09-03 | 2021-04-28 |
| Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation RFA - Papillary Thyroid Cancer, Papillary Thyroid Microcarcinoma | Not applicable | Completed | Mayo Clinic | 5 | 2020-06-15 | 2025-05-20 |
| SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma Stereotactic Body Radiation Therapy, radiofrequency ablation - Hepatocellular Carcinoma | Not applicable | Unknown | Sun Yat-sen University | 170 | 2020-06-01 | 2020-06-17 |
| Clinical Effect and Safety of PDT and RFA for Unresectable EHCC Photodynamic therapy, radiofrequency ablation - Cholangiocarcinoma | Not applicable | Completed | First People's Hospital of Hangzhou | 67 | 2020-03-01 | 2021-09-01 |
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Carcinoma, Hepatocellular (30) · Liver Neoplasms (10) · Cholangiocarcinoma (5) · Bile Duct Neoplasms (4) · Thyroid Neoplasms (3) · Biliary Tract Neoplasms (2) · Breast Neoplasms (2) · Colorectal Neoplasms (2) · Hyperthyroidism (2) · Lung Neoplasms (2) · Neoplasms (2) · Papillary Thyroid Microcarcinoma (2) · Thyroid Cancer, Papillary (2) · Thyroid Nodule (2) · Varicose Veins (2)
Sun Yat-sen University (13) · Southwest Hospital, China (6) · The First People's Hospital of Changzhou (4) · Mayo Clinic (3) · National Cancer Institute (NCI) (3) · American College of Radiology Imaging Network (2) · First People's Hospital of Hangzhou (2) · Ming Zhao (2) · Seoul National University Hospital (2) · The University of Hong Kong (2) · University Hospital, Ghent (2) · Aarhus University Hospital Skejby (1) · Acessa Health, Inc. (1) · All India Institute of Medical Sciences (1) · Amsterdam UMC, location VUmc (1)
China (32) · United States (15) · Belgium (3) · South Korea (3) · Brazil (2) · Germany (2) · Hong Kong (2) · India (2) · Netherlands (2) · Canada (1) · Czechia (1) · Denmark (1) · Israel (1) · Italy (1) · Poland (1)
Ming Kuang, Ph.D. (3) · Changping Wu, M.D. (2) · Ming Zhao, doctor (2) · Tim F Greten, M.D. (2) · Ajay Bansal, MD (1) · Andrea Bullock, MD, MPH (1) · Anil Kapoor, MD FRCSC (1) · Baogang Peng, MD (1) · Carlo Pappone, MD (1) · Damian E. Dupuy, MD (1) · Daniel Spratt, M.D. (1) · Daniela A Ochoa, MD (1) · David Eisenstein, MD (1) · David Wright, MD (1)
PMID 23269991, PMID 11923602, PMID 1309182, PMID 15915370, PMID 16250051, PMID 16495695, PMID 20041484, PMID 21311985, PMID 21403098, PMID 21839994, PMID 22438360, PMID 23096937, PMID 23426336, PMID 23874536, PMID 24293142, PMID 24919538, PMID 25668428, PMID 26291334, PMID 27488509, PMID 27816492, PMID 27920582, PMID 28500178, PMID 28842651, PMID 28923358, PMID 29333159, PMID 29342492, PMID 29650119, PMID 29962870, PMID 30111304, PMID 30578687, PMID 30688989, PMID 30905354, PMID 30908611, PMID 31647530, PMID 31939434, PMID 32795619, PMID 33104917, PMID 33471820, PMID 33510567, PMID 33556187, PMID 33767666, PMID 34297268, PMID 34313474, PMID 34454995, PMID 34995788, PMID 35085837, PMID 36968218, PMID 38205877, PMID 39090600, PMID 39240508
U01CA079778 (2), U01CA080098 (2), K23CA139005 (1), P30CA046592 (1), P30CA093373 (1), UG1CA242632 (1)