3 recruiting, 2 completed, 2 not yet recruiting, 1 active not recruiting. 4 Phase 2, 2 Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 1, Not yet recruiting 1 |
| Not applicable | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Reirradiation: new trials by email Literature Review of Reirradiation trials Research Report on Reirradiation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reirradiation and Total Ablative Strategies for Recurrent Gynecologic Cancer Reirradiation, Total Ablative Strategy - Recurrent Gynecologic Cancer, Recurrent Uterine Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-06-11 | 2026-10-16 | |
| aPBI Re-irradiation Reirradiation - Breast Cancer Recurrent | Phase 1 / Phase 2 | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 30 | 2026-06-03 | 2026-05-28 |
| Prospective RegIstry for Oncologic Reirradiation (PRIOR-DK) Reirradiation - Radiotherapy Side Effect | Not yet recruiting | University of Aarhus | 500 | 2026-04-01 | 2026-04-14 | |
| Ablative Stereotactic MR-Guided Adaptive Reirradiation Reirradiation - Abdominal Cancer, Pelvic Cancer | Not applicable | Active not recruiting | Baptist Health South Florida | 10 | 2024-06-05 | 2026-02-17 |
| Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study Lomustine, Reirradiation - First Progression of Glioblastoma | Phase 3 | Recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 411 | 2024-03-15 | 2026-06-08 |
| Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Association for Radiotherapy and Clinical Oncology (AIRO)-GI Platform: a Multi-centre Prospective Observational Study Reirradiation - Rectal Neoplasm | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 88 | 2023-06-21 | 2023-08-09 | |
| IMRT Combined With Toripalimab in Unresectable Locally Recurrent Nasopharyngeal Carcinoma. Tolipalimab, Reirradiation - Nasopharyngeal Carcinoma, Nasopharyngeal Neoplasms | Phase 2 | Unknown | Sun Yat-sen University | 25 | 2019-05-01 | 2022-04-29 |
| Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck Reirradiation, MK-3475 - Recurrent Head and Neck Cancer, Carcinoma, Squamous Cell of Head and Neck | Phase 2 | Completed | Dan Zandberg | 48 | 2016-03-09 | 2025-03-06 |
| Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT) Radiation Therapy - Brain Cancer | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 12 | 2011-12-07 | 2022-10-20 |
Head and Neck Neoplasms (2) · Brain Neoplasms (1) · Carcinoma, Squamous Cell (1) · Diffuse Intrinsic Pontine Glioma (1) · Fallopian Tube Neoplasms (1) · Fistula (1) · Glioblastoma (1) · Nasopharyngeal Carcinoma (1) · Nasopharyngeal Diseases (1) · Nasopharyngeal Neoplasms (1) · Ovarian Neoplasms (1) · Pelvic Neoplasms (1) · Radiation Injuries (1) · Rectal Neoplasms (1) · Recurrence (1)
Affidea Nu-med Center of Oncological DIagnostics and Therapy (1) · Baptist Health South Florida (1) · Dan Zandberg (1) · Dartmouth-Hitchcock Medical Center (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · M.D. Anderson Cancer Center (1) · Sun Yat-sen University (1) · University of Aarhus (1)
United States (4) · Italy (2) · Austria (1) · Belgium (1) · China (1) · Czechia (1) · Denmark (1) · France (1) · Germany (1) · Netherlands (1) · Norway (1) · Poland (1) · Spain (1) · Switzerland (1)
Dan Zandberg, MD (1) · Giuseppe Minniti, Dr. (1) · Matthias Preusser, Prof. (1) · Michael Chuong, M.D. (1) · Ming-Yuan Chen, MD,PhD (1) · Susan L. McGovern, MD (1)
PMID 34782428, PMID 38849943, PMID 39695675
R01CA187202 (1)