14 completed, 4 unknown, 1 withdrawn. 7 Not applicable, 6 Phase 2, 4 Phase 4, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Unknown 1 |
| Phase 2 | 6 | Completed 3, Unknown 2, Withdrawn 1 |
| Phase 4 | 4 | Completed 4 |
| Phase 3 | 3 | Completed 1, Unknown 1, Withdrawn 1 |
Follow red yeast rice: new trials by email Literature Review of red yeast rice trials Research Report on red yeast rice
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Middle Term Effect of Red Yeast Rice on Plasma Lipids and Proteoma in Individuals With Suboptimal Cholesterolemia Red yeast rice, Placebo - Hypercholesterolemia | Not applicable | Unknown | University of Bologna | 40 | 2024-05-02 | 2024-04-16 |
| Supplements, Placebo, or Rosuvastatin Study Fish Oil, Cinnamon, Garlique,Turmeric, Plant Sterol, Red Yeast Rice, Rosuvastatin, Placebo - Hypercholesterolemia | Phase 2 | Completed | The Cleveland Clinic | 203 | 2021-04-23 | 2023-05-25 |
| Effect of Red Yeast Rice Beside Statin on Lipid Profile Red Yeast Rice Pill, Placebo - Hyperlipidemias | Phase 4 | Completed | Shiraz University of Medical Sciences | 92 | 2019-03-01 | 2021-10-27 |
| Clinical Trial to Demonstrate the Efficacy of a Dietary Supplement in Decreasing Cardiovascular Risk Red Rice Yeast, Placebo Group - Low-Moderate Hypercholesterolemia | Not applicable | Completed | Bioksan | 100 | 2018-12-13 | 2022-07-21 |
| Red Rice Yeast in Low-density Lipoprotein (LDL) Lowering: an Efficacy Study Red Rice Yeast Extract, Statin - Dyslipidemias, LDL Hyperlipoproteinemia | Phase 2 | Unknown | Saint-Joseph University | 40 | 2018-02-07 | 2019-10-08 |
| The Efficacy and Safety of Combined Therapy With Red Yeast Rice and Low-dose Statin：Comparing With Standardized Statin Red yeast rice and atorvastatin, Atorvastatin alone - Dyslipidemia, Atherosclerosis | Phase 3 | Unknown | Wenzhou Medical University | 240 | 2015-11-01 | 2024-08-06 |
| Effects of 10 mg Monacolins on Vascular Health: a Clinical Trial Red yeast rice, Placebo - Atherosclerosis | Not applicable | Completed | University of Bologna | 40 | 2015-05-01 | 2024-02-01 |
| Lipid-lowering Effect of Phytosterols, Red Yeast Rice and Their Combination Plant sterols, Red Yeast Rice, Red Yeast Rice plus Plant sterols - Hypercholesterolemia | Not applicable | Completed | University of Bologna | 60 | 2015-04-01 | 2024-02-01 |
| Effects of a Supplement Derived From Palm Oil on Cholesterol Levels and Chinese Red Yeast Rice in the Blood Sugar Pill, Chinese Red Yeast Rice (CRYR), CRYR + TRF - Cholesterol Lowering | Phase 2 / Phase 3 | Withdrawn | University of California, Los Angeles | 2013-10-30 | 2019-01-11 | |
| Red Yeast Rice in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance Red yeast rice - Prostate Cancer | Phase 2 | Unknown | Dr. Laurence Klotz | 60 | 2013-01-01 | 2012-11-07 |
| the Effect of a Red Rice Nutrition Supplement on Cholesterol Levels red rice supplement - Cholesterol Level, HDL Level | Phase 4 | Completed | Universiteit Antwerpen | 52 | 2012-03-01 | 2012-09-17 |
| Effect of Gemfibrozil on the Safety and Pharmacokinetics of Red Yeast Rice in Healthy Subjects Gemfibrozil & red yeast rice (LipoCol) - Healthy Subjects | Phase 4 | Completed | National Taiwan University Hospital | 12 | 2011-07-01 | 2011-10-17 |
| The Role of a Combination of Nutraceuticals in the Control of Cardiovascular Risk Armolipid Prev - Metabolic Syndrome | Completed | Federico II University | 150 | 2010-09-01 | 2016-02-03 | |
| Armolipid Plus and Metabolic Syndrome Armolipid Plus - Metabolic Syndrome | Not applicable | Completed | Rottapharm | 66 | 2009-09-01 | 2010-09-02 |
| Red Yeast Rice and Phytosterols In Statin Intolerance red yeast rice, phytosterol, therapeutic lifestyle program - Hyperlipidemia | Phase 2 / Phase 3 | Completed | Chestnut Hill Health System | 200 | 2009-07-01 | 2011-07-18 |
| Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study nutraceutical combination (red yeast rice, policosanols and berberine) - Hypercholesterolemia | Phase 4 | Completed | Comitato Etico di Area Vasta Sud Est | 60 | 2009-01-01 | 2014-03-05 |
| Safety of Red Yeast Rice for High Cholesterol in Individuals With Statin Intolerance Red Yeast Rice, Pravastatin, Lifestyle modification program - Hypercholesterolemia, Statin-Associated Myopathy | Phase 2 | Completed | University of Pennsylvania | 43 | 2008-01-01 | 2010-01-18 |
| Lipid Lowering in Patients With Statin Intolerance red yeast rice, placebo - Hyperlipidemia, Coronary Artery Disease | Not applicable | Completed | Chestnut Hill Health System | 64 | 2007-01-01 | 2007-10-31 |
| Statin Therapy Vs. Therapeutic Lifestyle Changes and Supplements simvastatin, red yeast rice, pharmaceutical grade fish oil - Hyperlipidemia | Not applicable | Completed | Chestnut Hill Health System | 80 | 2006-04-01 | 2006-08-17 |
Hypercholesterolemia (5) · Hyperlipidemias (5) · Atherosclerosis (2) · Dyslipidemias (2) · Metabolic Syndrome (2) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Nutritional and Metabolic Diseases (1) · Patient Compliance (1) · Prostatic Neoplasms (1)
Chestnut Hill Health System (3) · University of Bologna (3) · Bioksan (1) · Comitato Etico di Area Vasta Sud Est (1) · Dr. Laurence Klotz (1) · Federico II University (1) · National Taiwan University Hospital (1) · Rottapharm (1) · Saint-Joseph University (1) · Shiraz University of Medical Sciences (1) · The Cleveland Clinic (1) · Universiteit Antwerpen (1) · University of California, Los Angeles (1) · University of Pennsylvania (1) · Wenzhou Medical University (1)
Italy (5) · United States (5) · Belgium (1) · Canada (1) · China (1) · Iran (1) · Lebanon (1) · Spain (1) · Taiwan (1)
David J Becker, MD (2) · Bruno Trimarco, MD (1) · Claudio Borghi, MD (1) · David Becker (1) · Jyh-Chin Yang, M.D. Ph.D. (1) · Kangting Ji, MD (1) · Laurence Klotz, MD (1) · Luke Laffin, M.D. (1) · Marouan Zoghbi (1) · Serafino Fazio, MD (1) · Steven C Halbert, MD (1) · Steven Nissen, M.D. (1) · Zhaopoing Li, MD, PhD (1)
PMID 19528562, PMID 23816039, PMID 23866314, PMID 26649075, PMID 27055107, PMID 28687937, PMID 29021813, PMID 36351465, PMID 36434733