6 completed, 2 recruiting, 1 terminated. 3 Phase 2, 2 Not applicable, 2 Phase 3, 1 Early Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Not applicable | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Pyridoxal Phosphate: new trials by email Literature Review of Pyridoxal Phosphate trials Research Report on Pyridoxal Phosphate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Efficacy of 100mg Vitamin-B6 Daily for Sensory Reactivity in Autism Pyridoxal 5'-Phosphate (100 mg), Placebo - Autism | Not applicable | Recruiting | University of Reading | 40 | 2024-11-08 | 2026-10-07 |
| Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency Pyridoxal Phosphate - Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency | Phase 3 | Recruiting | Medicure | 15 | 2024-02-16 | 2025-10-16 |
| Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults Adenosine Triphosphate, Acetylcholine, Sodium Nitroprusside - Receptor Blockade | Early Phase 1 | Completed | Colorado State University | 9 | 2019-02-07 | 2021-07-27 |
| Composition for Treating Uterine Fibroid (SB-UF) SB-UF, SB-UF Placebo - Uterine Fibroids Affecting Pregnancy | Phase 4 | Completed | Trieu, Nguyen Thi, M.D. | 66 | 2019-01-01 | 2026-06-08 |
| Safety and Efficacy of Pyridoxal 5' -Phosphate in the Treatment of Tardive Dyskinesia Pyridoxal 5'-Phosphate, Placebo - Tardive Dyskinesia | Phase 2 | Terminated | Medicure | 53 | 2009-05-01 | 2019-02-15 |
| A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG (MC-1) Pyridoxal 5'-phosphate - Coronary Artery Bypass Graft Surgery, Myocardial Ischemia | Phase 3 | Completed | Medicure | 3000 | 2006-11-01 | 2007-11-16 |
| Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx® Metanx® (Oral L-methylfolate, Methylcobalamin and Pyridoxal 5'-phosphate) - Diabetic Peripheral Neuropathy | Not applicable | Completed | Carolina Musculoskeletal Institute | 20 | 2006-06-01 | 2014-01-29 |
| MATCHED (MC-1 and ACE Therapeutic Combination for Hypertensive Diabetics) pyridoxal-5'-phosphate with and without ACE inhibitor - Diabetes Mellitus Type 2, Hypertension | Phase 2 | Completed | Medicure | 160 | 2004-08-01 | 2006-10-31 |
| MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery) (MC-1) Pyridoxal-5'-phosphate - Coronary Artery Bypass Graft Surgery, Myocardial Ischemia | Phase 2 | Completed | Medicure | 900 | 2004-04-01 | 2006-10-31 |
Ischemia (2) · Myocardial Ischemia (2) · Neurologic Manifestations (2) · Reperfusion Injury (2) · Autistic Disorder (1) · Diabetes Mellitus, Type 2 (1) · Hypertension (1) · Metabolic Syndrome (1) · Schizophrenia (1) · Tardive Dyskinesia (1)
Medicure (5) · Carolina Musculoskeletal Institute (1) · Colorado State University (1) · Trieu, Nguyen Thi, M.D. (1) · University of Reading (1)
United States (5) · Canada (4) · Australia (1) · India (1) · United Kingdom (1) · Vietnam (1)
Dr David T Field, PhD (1) · Frank Dinenno, PhD (1) · Gary J. Remington, MD, PhD (1) · Jean-Claude Tardif, MD, FRCPC, FACC (1) · Michel Carrier, MD (1) · Robert A Harrington, MD (1) · Thi Trieu Nguyen, Dr. (1) · Yves Lacourciere, MD, FRCP (1)