7 completed, 3 recruiting, 3 unknown, 2 terminated. 5 Not applicable, 4 Phase 2, 4 Phase 3, 3 Phase 4, 1 Phase 1.
Follow Premedication: new trials by email Literature Review of Premedication trials Research Report on Premedication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars Group B: patients will be given prednisolone 20mg as premedication, piroxicam 20mg - Irreversible Pulpitis With Apical Periodontitis, Symptomatic Apical Periodontitis | Phase 4 | Not yet recruiting | RANA AHMAD | 60 | 2026-01-01 | 2025-12-15 |
| Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy Premedication with n-acetylcysteine, Placebo (drinking water), Premedication with simethicone - Esophagogastroduodenoscopy, Simethicone | Phase 2 | Recruiting | Hospital General de Mexicali | 132 | 2025-09-12 | 2025-11-24 |
| Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors GEN1057, Premedication - Advanced Malignant Solid Tumors, Metastatic Malignant Solid Tumors | Phase 1 | Terminated | Genmab | 23 | 2024-08-28 | 2026-10-07 |
| Rituximab Therapy in Anti-Myelin Associated Glycoprotein Patients With Characteristics of Good Responders Rituximab infusion, Placebo infusion, Premedications - Anti-MAG Neuropathy | Phase 3 | Recruiting | Centre Hospitalier Universitaire de Saint Etienne | 90 | 2023-06-29 | 2025-11-24 |
| Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF Obinutuzumab administration, Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil, Administration of methylprednisolone, paracetamol and dexchlorpheniramine - Lupus Nephritis, Systemic Lupus Erythematosus (SLE) | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 196 | 2021-12-09 | 2025-11-24 |
| Efficacy of iv Fentanyl Citrate Administered Oral as a Pediatric Premedication Oral premedication - Anesthesia, Local | Not applicable | Unknown | University of Alexandria | 60 | 2021-06-01 | 2021-08-05 |
| Pregabalin Premedication for Knee Arthroscopy Pregabalin (PG), Control placebo (C) - Knee Arthroscopy | Not applicable | Unknown | Menoufia University | 112 | 2019-06-01 | 2019-04-25 |
| Prediction of Volume Responsiveness in Presence of Left Ventricular Diastolic Dysfunction passive leg raising, premedication, intubation and mechanical ventilation - Hemodynamics | Not applicable | Unknown | University Hospital Schleswig-Holstein | 50 | 2015-06-01 | 2015-05-12 |
| Pregabalin Premedication for Conscious Sedation Pregabalin (PG), Control placebo (C) - Conscious Sedation | Not applicable | Completed | Menoufia University | 70 | 2015-04-15 | 2018-01-02 |
| Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients Gabapentin as premedication, placebo - Post Operative Nausea and Vomiting (PONV), Adenotonsillectomy | Phase 3 | Completed | Cairo University | 140 | 2015-01-01 | 2015-12-23 |
| Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004) Vintafolide 2.5 mg, Paclitaxel 80 mg/m^2, Etarfolatide - Breast Neoplasms | Phase 2 | Withdrawn | Endocyte | 2014-04-01 | 2014-12-19 | |
| Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery dexmedetomidine infusion for premedication, Midazolam, saline infusion - Chronic Renal Failure, Hip Fracture | Phase 3 | Completed | Baskent University | 60 | 2012-12-01 | 2015-01-27 |
| Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy Propranolol, DOT imaging, Paclitaxel - Locally Advanced Malignant Neoplasm, Breast Cancer | Phase 2 | Completed | Columbia University | 10 | 2012-10-01 | 2021-09-10 |
| Intrathecal Morphine for Inguinal Hernia Repair. intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg, intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg, standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland - Inguinal Hernia, Nausea | Phase 4 | Completed | Ankara University | 46 | 2009-07-01 | 2013-12-05 |
| Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery Midazolam, Ropivacaine, Fentanyl - Upper Extremity, Orthopedic Surgery | Phase 4 | Completed | University of Parma | 52 | 2008-05-01 | 2009-07-15 |
| Study of Effectiveness of Thoracic Epidural Analgesia for the Prevention of Acute Pancreatitis After ERCP Procedures ERCP, Thoracic epidural analgesia, Premedication - Post-ERCP Acute Pancreatitis | Not applicable | Completed | Volgograd State Medical University | 491 | 2008-01-01 | 2020-10-19 |
| Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck Docetaxel, Capecitabine, Premedication - Head and Neck Cancer | Phase 2 | Terminated | Hoosier Cancer Research Network | 19 | 2004-03-01 | 2011-05-02 |
Breast Neoplasms (2) · Vomiting (2) · Forearm Injuries (1) · Head and Neck Neoplasms (1) · Hernia, Inguinal (1) · Hip Fractures (1) · Kidney Failure, Chronic (1) · Lupus Erythematosus, Systemic (1) · Lupus Nephritis (1) · Nausea (1) · Pain, Postoperative (1) · Postoperative Nausea and Vomiting (1) · Pruritus (1) · Renal Insufficiency (1) · Stomach Neoplasms (1)
Menoufia University (2) · Ankara University (1) · Assistance Publique - Hôpitaux de Paris (1) · Baskent University (1) · Cairo University (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Columbia University (1) · Endocyte (1) · Genmab (1) · Hoosier Cancer Research Network (1) · Hospital General de Mexicali (1) · RANA AHMAD (1) · University Hospital Schleswig-Holstein (1) · University of Alexandria (1) · University of Parma (1)
United States (3) · Egypt (2) · France (2) · Turkey (Türkiye) (2) · Germany (1) · Italy (1) · Japan (1) · Mexico (1) · Russia (1) · Spain (1)
Anis Aribogan, Prof., MD (1) · Basak Ceyda Meco (1) · David Potter, M.D. (1) · Giorgio Danelli, MD (1) · Guido Fanelli, MD (1) · Kevin M. Kalinsky, MD, MS (1) · Mihail Turovets, PhD (1) · Mohamed Abdulatif, Professor of Anesthesia (1) · Ole Broch, MD (1)
PMID 24325147, PMID 26323728, PMID 29971260, PMID 31044749, PMID 32016519, PMID 33693991, PMID 37010198
UL1TR000040 (1)