7 completed, 2 not yet recruiting. 6 Not applicable, 1 Phase 2, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Not yet recruiting 2 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Placebo toothpaste: new trials by email Literature Review of Placebo toothpaste trials Research Report on Placebo toothpaste
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bio-Descaling Toothpaste for Dental Calculus Reduction Bio-Descaling Powder (BDP) Toothpaste, Placebo toothpaste - Dental Calculus, Gingivitis and Periodontal Diseases | Not applicable | Not yet recruiting | Universidad Complutense de Madrid | 100 | 2026-07-01 | 2026-07-08 |
| Chios Mastic Toothpaste and Halitosis and Oral Hygiene in Orthodontic Patients mastic toothpaste, Placebo toothpaste - Halitosis, Orthodontic Appliance Complication | Not applicable | Not yet recruiting | University of Athens | 30 | 2025-01-07 | 2025-01-09 |
| Effect of Nigella Sativa Toothpaste on Salivary Biomarkers in Patients With Gingivitis Nigella sativa toothpaste, Placebo toothpaste - Gingivitis | Not applicable | Completed | Universitas Airlangga | 100 | 2023-01-01 | 2026-03-03 |
| Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity Placebo, 15% nano-HAP toothpaste, 5% KNO3 toothpaste - Dentin Sensitivity | Not applicable | Completed | The University of Texas Health Science Center at San Antonio | 192 | 2020-07-28 | 2023-08-16 |
| Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers Placebo toothpaste, triclosan/copolymer/fluoride toothpaste - Dental Implants, Cigarette Smoking | Not applicable | Completed | Paulista University | 26 | 2013-07-01 | 2017-08-07 |
| Impact of a Triclosan-containing Toothpaste During the Progression of Experimental Peri-implant Mucositis Placebo toothpaste, triclosan/copolymer/fluoride toothpaste - Biological Markers; Dental Implants; Cytokines; Triclosan; Toothpastes; Peri-Implantitis; Microbiology | Not applicable | Completed | Paulista University | 22 | 2013-06-01 | 2017-05-09 |
| Efficacy and Safety Study of Yunnan Baiyao on Minor Recurrent Aphthous Stomatitis Yunnan Baiyao toothpaste, Placebo toothpaste - Recurrent Aphthous Stomatitis | Phase 2 | Completed | Peking University | 227 | 2010-03-01 | 2012-07-30 |
| Dose Response of a Tubule Occlusion Agent 5% calcium sodium phosphosilicate toothpaste, 7.5% calcium sodium phosphosilicate toothpaste, Placebo toothpaste - Dentine Hypersensitivity, Dental Pain | Phase 4 | Completed | GlaxoSmithKline | 195 | 2008-12-01 | 2013-06-03 |
| In Situ Caries of Fluoride Toothpastes Sodium fluoride toothpaste, Placebo toothpaste - Healthy Subjects, Partial Denture Wearers | Phase 3 | Completed | GlaxoSmithKline | 60 | 2007-11-01 | 2013-04-22 |
Dentin Sensitivity (2) · Gingivitis (2) · Bites and Stings (1) · Cigarette Smoking (1) · Dental Calculus (1) · Halitosis (1) · Hypersensitivity (1) · Peri-Implantitis (1) · Periodontal Diseases (1) · Stomatitis, Aphthous (1) · Toothache (1)
GlaxoSmithKline (2) · Paulista University (2) · Peking University (1) · The University of Texas Health Science Center at San Antonio (1) · Universidad Complutense de Madrid (1) · Universitas Airlangga (1) · University of Athens (1)
United States (2) · Brazil (1) · Greece (1) · Indonesia (1)
Bennett T Amaechi, BDS, MS, PhD (1) · Iosif Sifakakis, Associate Professor (1)