8 completed, 1 not yet recruiting, 1 terminated. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 8, Not yet recruiting 1, Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow Pentamidine: new trials by email Literature Review of Pentamidine trials Research Report on Pentamidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Topical Paromomycin for Cutaneous Leishmaniasis in Bolivia Paromomycin Sulfate, Pentamidine Isethionate, Placebo - Leishmaniasis, Cutaneous, Leishmania Braziliensis Complex | Phase 2 / Phase 3 | Completed | Fundacion Nacional de Dermatologia | 80 | 2017-04-15 | 2021-02-02 |
| Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study Pentamidine - Visceral Leishmaniosis, HIV-infection/Aids | Phase 3 | Completed | Institute of Tropical Medicine, Belgium | 74 | 2011-11-01 | 2019-02-15 |
| A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides Pentamidine isethionate, Dapsone - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 400 | 2021-11-01 | |
| A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS Pentamidine isethionate, Sulfamethoxazole-Trimethoprim - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 240 | 2021-11-03 | |
| A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX Atovaquone, Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | Glaxo Wellcome | 615 | 2005-06-24 | |
| A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients Pentamidine isethionate, Sulfamethoxazole-Trimethoprim, Dapsone - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 600 | 2021-11-04 | |
| A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT) Pentamidine isethionate, Pyrimethamine, Sulfamethoxazole/Trimethoprim - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 322 | 2021-11-03 | |
| Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Trimetrexate glucuronate, Pentamidine isethionate, Sulfamethoxazole-Trimethoprim - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 364 | 2021-11-04 | |
| Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients Trimetrexate glucuronate, Methylprednisolone, Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Phase 3 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 240 | 2021-11-03 |
Acquired Immunodeficiency Syndrome (8) · HIV Infections (7) · Pneumonia, Pneumocystis (7) · AIDS-Related Opportunistic Infections (5) · AIDS-Related Complex (3) · Leishmaniasis, Cutaneous (2) · Respiratory Aspiration (2) · Leishmaniasis (1) · Leishmaniasis, Mucocutaneous (1) · Leishmaniasis, Visceral (1) · Recurrence (1) · Toxoplasmosis (1)
National Institute of Allergy and Infectious Diseases (NIAID) (6) · Institute of Tropical Medicine, Belgium (2) · Fundacion Nacional de Dermatologia (1) · Glaxo Wellcome (1)
United States (7) · Ethiopia (2) · Bolivia (1) · Tanzania (1)
B Montgomery (1) · El-Sadr W (1) · Ermias Diro, MD (1) · Hardy WD (1) · Holzman R (1) · Johan Van Griensven (1) · Johan Van Griensven, MD, PhD (1) · Luskin-Hawk R (1) · Masur H (1) · S Bozzette (1) · S Spector (1) · Sattler FR (1)