Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan

NCT05106803 — Completed, 24 participants, Yarmouk University

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Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan

RegistryNCT05106803
StatusCompleted
Study typeObservational
Enrollment24 (Actual)
SponsorYarmouk University (Other)
ConditionsBacterial Infections, Antibiotic Resistant Infection, Surgical Site Infection
Interventionsciprofloxacin (Drug)
Datesstart 2019-08-01, primary completion 2019-10-01, completion 2019-10-01, first posted 2021-11-04, last updated 2021-11-04
Locations1 site in Jordan

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-Summary

The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.

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+Detailed description

Background: Surgical site infections are hospital-acquired, vary from one hospital to another, and can cause significant postoperative morbidity, mortality, and prolonged hospital stay.

Aim: The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.

Methods: Postsurgical wound samples were collected and processed in a microbiology laboratory using standard microbiological techniques. Antibiotic susceptibility tests were performed using 13 antibiotics covering the gram-positive and gram-negative bacteria using the disc diffusion test.

+Arms and interventions

ArmTypeInterventionsDescription
Wound infectionDrug: ciprofloxacinPatients with surgical site infection as diagnosed by the attending physician
  • ciprofloxacin (Drug), also known as trimethoprim-sulfamethoxazole, norfloxacin, erythromycin, chloramphenicol, gentamicin, tetracycline, vancomycin, amoxicillin/clavulanic acid, cefepime, penicillin, ampicillin, clindamycin, oxacillin: Antibiotics used in vitro n the study

+Outcome measures

Primary outcomes

  • Positive culture [August 2019 to October 2019]: Positive swab culture from the wound

Secondary outcomes

  • Gram stain and type of Bacteria [August 2019 to October 2019]: Gram stain and type of Bacteria grown in culture media
  • Antibiotic Susceptibility [August 2019 to October 2019]: Antibiotic Susceptibility to the isolated organisms

+Eligibility

Sex: All

Inclusion Criteria:

* Post-Surgical Wound Infection

Exclusion Criteria:

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+Locations (1)

FacilityCityCountryStatus
Yarmouk UniversityIrbidJordan

+Investigators

  • Raed M Ennab, Principal investigator, Department of Clinical Sciences, Faculty Of Medicine, Yarmouk University