pegaptanib: Clinical Trials

43 trials of pegaptanib, newest first

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27 completed, 7 terminated, 5 unknown, 3 withdrawn. 11 Phase 4, 10 Phase 2, 9 Phase 3, 6 Not applicable, 4 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 411Completed 5, Terminated 3, Unknown 3
Phase 210Completed 8, Terminated 2
Phase 39Completed 7, Unknown 1, Withdrawn 1
Not applicable6Completed 3, Terminated 2, Withdrawn 1
Phase 14Completed 2, Terminated 2

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Cohort Study of the Clinical Course of Macular Diseases in Kagawa
ranibizumab, aflibercept, pegaptanib, verteporphin - Macular Disease
Phase 4UnknownKagawa University10002014-12-012018-03-07
Cohort Study of the Clinical Course of Macular Diseases in Japanese
ranibizumab, aflibercept, pegaptanib, verteporphin - Macular Disease
UnknownKyoto University, Graduate School of Medicine10002014-03-012016-09-23
A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy
Macugen, Sham - Proliferative Diabetic Retinopathy
Phase 3WithdrawnGreater Houston Retina Research2012-04-012014-03-05
A Single-Center Trial of Intravitreous Injections of Macugen (Pegaptanib Sodium) Given at Least 7 Days Before Vitrectomy Secondary To Tractional Retinal Detachment in Proliferative Diabetic Retinopathy
Macugen (Pegaptanib Sodium) - PDR
Phase 1CompletedRetina Institute of Hawaii52011-04-012011-12-07
Intravitreal Macugen for Ischaemic Diabetic Macular Oedema
Intravitreal injection of pegaptanib sodium - Diabetic Macular Oedema
Phase 4CompletedUniversity of Oxford302011-01-012014-12-24
Study To Evaluate Safety And Tolerability Of Pegaptanib Sodium In Patients With Diabetic Macular Edema
pegaptanib sodium - Anti- VGF Inhibitor, Diabetic Macular Edema
Phase 3CompletedPfizer462011-01-012013-09-06
Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic Myopia
Intravitreal Pegaptanib - Myopic Choroidal Neovascular Membrane
Not applicableWithdrawnL.V. Prasad Eye Institute2010-12-012015-09-02
A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema
pegaptanib sodium, sham injection - Macular Edema, Diabetic Mellitus
Phase 3CompletedPfizer2432010-05-012013-08-23
Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium
pegaptanib sodium injection - Age-Related Macular Degeneration, Retinal Vein Occlusion
Phase 4CompletedBausch & Lomb Incorporated1312010-04-222021-01-08
Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study
Macugen® pegaptanib sodium - Diabetic Macular Edema
Phase 4CompletedValley Retina Institute722009-04-012013-07-16
Pegaptanib Therapy in Non-Infectious Uveitic Cystoid Macular Edema
Pegaptanib - Uveitis, Cystoid Macular Edema
Not applicableCompletedWake Forest University52009-03-012022-03-15
Long-Term Use Of Pegaptanib In Patients For Subfoveal Choroidal Neovascularization Secondary To Age-Related Macular Degeneration
Pegaptanib sodium - Macular Degeneration
CompletedPfizer35382008-11-012015-10-02
Subretinal Macugen® for Neovascular Age-Related Macular Degeneration
Pegaptanib (Macugen®) - Age-related Macular Degeneration
Phase 3UnknownKlinikum Ludwigshafen102008-11-012011-09-27
The Effect of a Single Intravitreal Anti-VEGF Therapy on Optic Nerve Head Perfusion
ranibizumab, bevacizumab or pegaptanib - Macular Degeneration, Regional Blood Flow
Not applicableTerminatedMedical University of Vienna82008-03-012014-11-14
Efficacy And Safety Of Macugen In Patients With Neovascular AMD In Routine Clinical Practice.
pegaptanib sodium - Neovascular Age-related Macular Degeneration
CompletedPfizer862008-03-012012-04-11
Efficacy, Safety, Tolerability of Pegaptanib Sodium (Macugen) in Filipino Patients With Neovascular Age Related Macular Degeneration.
Macugen - Neovascular Age-related Macular Degeneration
WithdrawnPfizer2008-02-012015-03-05
Macugen for Proliferative Diabetic Retinopathy Study With Extended Dosing (M-PDRS ED)
Macugen ® (pegaptanib sodium) - Proliferative Diabetic Retinopathy
Phase 4UnknownValley Retina Institute302007-11-012011-12-06
A Study On The Efficacy Of Macugen Injections In Patients With Neovascular Age-Related Macular Degeneration In Real Life.
Macugen - Neovascular Age-related Macular Degeneration
CompletedPfizer382007-11-012018-12-06
Effect of Macugen(Pegaptanib)on Surgical Outcomes and VEGF Levels in Diabetic Patients With PDR (Diabetic Retinopathy or CSDME (Macular Edema)
Macugen (pegaptanib), Macugen (Pegaptanib) - Proliferative Diabetic Retinopathy, Diabetic Macular Edema
Not applicableCompletedLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's282006-10-012012-04-19
Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration
Macugen - Macular Degeneration
CompletedPfizer5012006-08-012012-12-11

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Conditions studied

Macular Degeneration (21)  ·  Macular Edema (5)  ·  Choroidal Neovascularization (3)  ·  Retinal Vein Occlusion (3)  ·  Diabetic Retinopathy (2)  ·  Ischemia (1)  ·  Retinal Diseases (1)  ·  Uveitis (1)  ·  Vitreous Hemorrhage (1)

Sponsors

Pfizer (13)  ·  Eyetech Pharmaceuticals (9)  ·  Johns Hopkins University (2)  ·  Retina Institute of Hawaii (2)  ·  Valley Retina Institute (2)  ·  Barnes Retina Institute (1)  ·  Bausch & Lomb Incorporated (1)  ·  Greater Houston Retina Research (1)  ·  Hermann Eye Center (1)  ·  Kagawa University (1)  ·  Klinikum Ludwigshafen (1)  ·  Kyoto University, Graduate School of Medicine (1)  ·  L.V. Prasad Eye Institute (1)  ·  London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1)  ·  Medical University of Vienna (1)

Countries

United States (19)  ·  Japan (5)  ·  Austria (4)  ·  France (4)  ·  Germany (4)  ·  Greece (4)  ·  United Kingdom (4)  ·  Belgium (3)  ·  Canada (3)  ·  Czechia (3)  ·  Denmark (3)  ·  Italy (3)  ·  Spain (3)  ·  Finland (2)  ·  India (2)

Top investigators

Akiataka Tsujikawa, MD (1)  ·  Diana V. Do, MD (1)  ·  Gaurav K Shah, MD (1)  ·  Ilse Krebs, MD (1)  ·  James C Major, MD (1)  ·  John A Wells, III, MD (1)  ·  Lars-Olof Hattenbach, MD (1)  ·  Mandeep Kaur, M.D. (1)  ·  Michael D Bennett, MD (1)  ·  Nagahisa Yoshimura, MD (1)  ·  Oliver D. Schein, MD, MPH, MBA (1)  ·  Raja Narayanan, MD (1)

Results publications

PMID 19365011, PMID 20472746, PMID 21896838, PMID 22872673, PMID 24997182, PMID 25187694, PMID 37260074